Correlation of a chicken stage 4 neural plate fate map with early gene expression patterns

Puelles, Luis; Fernández-Garre, Pedro; Sánchez-Arrones, Luisa; Garcı́a-Calero, Elena; Rodríguez‐Gallardo, Lucía

doi:10.1016/j.brainresrev.2004.12.036

Cited by 23 publications

(19 citation statements)

References 49 publications

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“…Ciona embryos develop from defined cell lineages, and the gene expression patterns that underlie important embryological boundaries form relatively early in development. In vertebrates, neural territories are composed of mixed fate cell populations, which segregate and form boundaries according to fate at comparatively later developmental stages in response to diverse signals, including FGFs (Puelles et al, 2005;Toro and Varga, 2007;Cajal et al, 2012;Sanchez-Arrones et al, 2012). Despite these differences, a common requirement for FGF signaling highlights the relevance of Ciona embryos to the study of patterning and the morphogenetic mechanisms underlying vertebrate development.…”

Section: Research Articlementioning

confidence: 99%

FGF signaling establishes the anterior border of the Ciona neural tube

2012

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SUMMARYThe Ciona tadpole is constructed from simple, well-defined cell lineages governed by provisional gene networks that have been defined via extensive gene disruption assays. Here, we examine the patterning of the anterior neural plate, which produces placodal derivatives such as the adhesive palps and stomodeum, as well as the sensory vesicle (simple brain) of the Ciona tadpole. Evidence is presented that the doublesex-related gene DMRT is expressed throughout the anterior neural plate of neurulating embryos. It leads to the activation of FoxC and ZicL in the palp placode and anterior neural tube, respectively. This differential expression depends on FGF signaling, which inhibits FoxC expression in the anterior neural tube. Inhibition of FGF signaling leads to expanded expression of FoxC, the loss of ZicL, and truncation of the anterior neural tube.

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Section: Research Articlementioning

confidence: 99%

FGF signaling establishes the anterior border of the Ciona neural tube

2012

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“…Together, these findings demonstrate that molecular regionalisation and, in particular, classical surface ectoderm and forebrain markers, do not strictly define lineages at late gastrulation stage. In the mouse, the establishment of strict clonal boundaries appears to be a later event that could arise by progressive restriction of cell dispersion, rather than by a process of lineage specification, resulting from distinct combination of prepattern factors (Fraser et al, 1990;Inoue et al, 2000;Mathis and Nicolas, 2002;Puelles et al, 2005;Veitia and Salazar-Ciudad, 2007).…”

Section: Organisation Of the Progenitors And Molecular Regionalisatiomentioning

confidence: 99%

Clonal and molecular analysis of the prospective anterior neural boundary in the mouse embryo

et al. 2012

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SUMMARYIn the mouse embryo the anterior ectoderm undergoes extensive growth and morphogenesis to form the forebrain and cephalic non-neural ectoderm. We traced descendants of single ectoderm cells to study cell fate choice and cell behaviour at late gastrulation. In addition, we provide a comprehensive spatiotemporal atlas of anterior gene expression at stages crucial for anterior ectoderm regionalisation and neural plate formation. Our results show that, at late gastrulation stage, expression patterns of anterior ectoderm genes overlap significantly and correlate with areas of distinct prospective fates but do not define lineages. The fate map delineates a rostral limit to forebrain contribution. However, no early subdivision of the presumptive forebrain territory can be detected. Lineage analysis at single-cell resolution revealed that precursors of the anterior neural ridge (ANR), a signalling centre involved in forebrain development and patterning, are clonally related to neural ectoderm. The prospective ANR and the forebrain neuroectoderm arise from cells scattered within the same broad area of anterior ectoderm. This study establishes that although the segregation between non-neural and neural precursors in the anterior midline ectoderm is not complete at late gastrulation stage, this tissue already harbours elements of regionalisation that prefigure the later organisation of the head.

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“…It has been shown that BMP2 and BMP4 are highly expressed in the germinal crescent region of the chicken embryo (Gallego-Díaz et al, 2002;Puelles et al, 2005). Thus, early germ cell development in both mice and chickens occurs in a BMP-positive extracellular environment.…”

Section: Germ Cell-specific Genes and Determinants Identified In Chickenmentioning

confidence: 99%

“…BMP2 increases cell reactivity to SSEA1. (Gallego-Díaz et al, 2002;Puelles et al, 2005;Kim et al, 2006).…”

Section: Cnanogmentioning

confidence: 99%

Primordial Germ Cell Technologies for Avian Germplasm Cryopreservation and Investigating Germ Cell Development

Glover

McGrew

2012

J. Poult. Sci.

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The germ cell lineage is unique as it is the cell lineage that ensures the continuation and the variation of genetic information from one generation to the next. Primordial germ cells are the stem cell precursors of this lineage differentiating into mature spermatozoa and oocytes in the adult. The recent development of cell culture conditions for the extended propagation of chicken primordial germ cells isolated from embryonic blood heralds the emergence of a technology that will have a considerable impact on the management of avian resources, efforts in avian species preservation and transgenic technologies. This review will address what is known of the formation of avian germ cells, the current state of the field, and discuss the prospects that this technology offers for both developmental biology and the preservation of avian germplasm.

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Correlation of a chicken stage 4 neural plate fate map with early gene expression patterns

Cited by 23 publications

References 49 publications

FGF signaling establishes the anterior border of the Ciona neural tube

FGF signaling establishes the anterior border of the Ciona neural tube

Clonal and molecular analysis of the prospective anterior neural boundary in the mouse embryo

Primordial Germ Cell Technologies for Avian Germplasm Cryopreservation and Investigating Germ Cell Development

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