Correlation distance dependence of the resonance frequency of intermolecular zero quantum coherences and its implication for MR thermometry

Zhang, Le; McCallister, Andrew; Koshlap, Karl M.; Branca, Rosa T.

doi:10.1002/mrm.26801

Cited by 2 publications

(1 citation statement)

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“…One particular type of iMQC signal, the intermolecular zero quantum coherence (iZQC), evolves at the difference in frequency between water and methylene protons, resulting in removal of some inhomogeneous broadening at the microscopic level, and possibly enabling absolute temperature measurements in the tissue (132). In practice, this is precluded by the much higher sensitivity of the water-fat iZQC frequency to the specific water-fat distribution at the microscopic level (187).…”

Section: H-based Mr Thermometry [Recently Proposed Technique]mentioning

confidence: 99%

Magnetic Resonance Imaging Techniques for Brown Adipose Tissue Detection

Junker

Branca

et al. 2020

Front. Endocrinol.

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Magnetic resonance imaging (MRI) and magnetic resonance spectroscopy (MRS) methods can non-invasively assess brown adipose tissue (BAT) structure and function. Recently, MRI and MRS have been proposed as a means to differentiate BAT from white adipose tissue (WAT) and to extract morphological and functional information on BAT inaccessible by other means. Specifically, proton MR (1 H) techniques, such as proton density fat fraction mapping, diffusion imaging, and intermolecular multiple quantum coherence imaging, have been employed to access BAT microstructure; MR thermometry, relaxometry, and MRI and MRS with 31 P, 2 H, 13 C, and 129 Xe have shown to provide complementary information on BAT function. The purpose of the present review is to provide a comprehensive overview of MR imaging and spectroscopy techniques used to detect BAT in rodents and in humans. The present work discusses common challenges of current methods and provides an outlook on possible future directions of using MRI and MRS in BAT studies.

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Section: H-based Mr Thermometry [Recently Proposed Technique]mentioning

confidence: 99%