Correlation between Xerostomia index, Clinical Oral Dryness Scale, and ESSPRI with different hyposalivation tests

Hijjaw, Ola; Alawneh, Mohammad; Ojjoh, Khaled; Abuasbeh, Hazem; Alkilany, Ahmad; Qasem, Nabeel; Al-Essa, Mohammad; AlRyalat, Saif Aldeen

doi:10.2147/oarrr.s188937

Cited by 9 publications

(7 citation statements)

References 27 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Though the XI data were not correlated to the objective salivation tests of Hijjaw et al . ( 22 ), regardless of hyposalivation, xerostomia poses a problem per se, as it had an effect on feeling healthy, with xerostomia observed in 69.9 % of respondents in this study reporting bad or very bad self-perceived health. The logistic regression analysis showed an association between the dry mouth sensation and several systemic diseases and psychological disorders.…”

Section: Discussionmentioning

confidence: 52%

Association between xerostomia, oral and general health, and obesity in adults. A cross-sectional pilot study

Pérez-González¹,

Ja²,

Rey³

et al. 2021

Med Oral

View full text Add to dashboard Cite

Background The objective of this study was to analyse the association between oral and general health variables and obesity indicators with the sensation of dry mouth or xerostomia as evaluated on the Xerostomia Inventory (XI). Material and Methods A total of 354 randomly selected subjects participated in this cross-sectional pilot study and completed an anonymous questionnaire. Anthropometric, clinical, and xerostomic variables were evaluated. Kruskal-Wallis, ANOVA and Bonferroni test were used for multiple comparisons. ROC curves and multinomial logistic regression were used to determine the (OR) risk of xerostomia. Results A total of 30.7 % of respondents reported xerostomia based on XI. The dry mouth question, the XI taken as a “gold standard”, showed a diagnostic sensitivity of 70.37 %, and a specificity of 83.27 % (AUC=0.768, p <0.001). Logistical regression showed the highest xerostomia OR was associated to patients with bad self-perceived health, 6.31 (CI 95% 2.89-13.80, p <0.001). In the model adjusted for tooth mobility, bone or respiratory diseases, and the consumption of anxiolytics and antidepressants, the OR was 3.46 (CI 95% 1.47-8.18, p =0.005). Conclusions a high prevalence of xerostomia was found in this cross-sectional pilot study, which was significantly more frequent in women, and increased with age. Xerostomia was associated to several systemic diseases, psychological conditions, and oral functional disorders such as tooth mobility. These preliminary results can serve as the basis for developing guidelines for the application of innovative measures designed to improve the quality of life of individuals with xerostomia. Key words: Xerostomia, systemic pathology, oral health, obesity, geriatrics.

show abstract

Section: Discussionmentioning

confidence: 52%

Association between xerostomia, oral and general health, and obesity in adults. A cross-sectional pilot study

Pérez-González¹,

Ja²,

Rey³

et al. 2021

Med Oral

View full text Add to dashboard Cite

show abstract

“…3 Hijjaw O et al in their research found the mean stimulated whole saliva flow rate as 0.46 (±0.44) mL/5min which is slightly higher than that seen in present study. 10 In the present study, a negative weak correlation was observed between CODS and SFR (r=-0.281). Hence the results suggest that flow of saliva significantly decreased when the COD score increased (p<0.05).…”

Section: Discussionsupporting

confidence: 44%

“…3 Hence, literature has shown varying results such as weak to no correlation between mouth dryness and SFR. 5,[10][11][12] In Pakistan, there is lack of baseline data, and international data isn't applicable in our population due to variation in genetic and personal habits. Therefore, the aim of current study was to evaluate the mean CODS and SFR among…”

mentioning

confidence: 99%

Correlation Between Clinical Oral Dryness Score and Salivary Flow Rates in Active and Passive Smokers

Nigar¹,

Hassan²,

Fahim³

et al. 2021

J. Bahria Univ. Med. Dent. Coll.

View full text Add to dashboard Cite

Objective: To evaluate the mean clinical oral dryness score (CODs) and salivary flow rate (SFR) in subjects exposed to active and passive smoking. The secondary aim was to determine the correlation between CODs and SFR and potential factors associated with CODs and SFR in our subjects. Study Design and Setting: The clinical observational study was conducted at the Outpatient department of oral diagnosis at Altamash Institute of Dental Medicine, Karachi from Jan 2019-Jul 2019. Methodology: A total of 217 participants of ages 15 – 80years coming for routine dental checkup of either gender were included. A thorough oral examination was performed for all the subjects. A non-stimulated saliva sample was collected from the oral cavity of subjects in a graduated container. The salivary flow rate was noted in ml/min for 5 minutes. Assessment of oral dryness/hypo-salivation was examined through CODs (clinical oral dryness score).The data were analyzed using SPSS software version 23. Results: The mean COD score and SFR were calculated as 1 and 0.42 ml/5min respectively. The Pearson’s correlation between COD score and SFR level was calculated as -0.281 (negative correlation) such as the SFR significantly decreased when the COD score increased (p<0.05). The age, gender, smoking status, betel quid and areca nut consumption showed statistically significant difference in mean COD score and SFR levels (p<0.05). Conclusion: Salivary flow rate was significantly decreased with increase in COD score thus having an implication on oral dryness feeling in these participants.

show abstract

“…In contrast, a previous study observed that significant xerostomia, reduction in salivary flow rate and flavor alteration were all evident in HIV-positive patients receiving highly active antiretroviral therapy (HAART). 39 As seen in the present study, Xerostomia, a subjective complaint of dry mouth, is not always correlated to hyposalivation as objective reduction of salivary flow rates 40,41 . Xerostomia can also be experienced by patients with a normal salivary flow rate.…”

Section: Discussionmentioning

confidence: 43%

Analysis of the relationship between human cytomegalovirus DNA and gB-1 genotype in the saliva of HIV/AIDS patients with xerostomia and salivary flow rate

Sufiawati¹,

Suniti²,

Nelonda³

et al. 2019

Dent. J.

View full text Add to dashboard Cite

Background: Human immunodeficiency virus (HIV) infection increases vulnerability to opportunistic viral infection, including Human cytomegalovirus (HCMV) infection, that has been detected in saliva. The HCMV envelope glycoprotein B (gB) is highly immunogenic and has been associated with HCMV-related diseases. Purpose: The purpose of this study is to assess the prevalence of HCMV and gB-1 genotype in the saliva of HIV/AIDS patients and to analyse their relationship with xerostomia and salivary flow rate (SFR). Methods: This cross-sectional study involved 34 HIV/AIDS patients. Saliva was tested for the presence of HCMV DNA using PCR microarrays, and nested PCR for gB-1 genotype detection. Xerostomia was measured using a Fox’s questionnaire. Unstimulated whole saliva flow rate was measured by means of the spitting method. Results: The composition of the research population consisting of 73.5% males and 26.5% females with HIV/AIDS. HCMV was found in 64.7% of HIV/AIDS patients, while gB-1 genotype was detected in 59.1%. Xerostomia was closely associated with the presence of HCMV in saliva (p<0.05), but not with gB-1. There was no significant relationship between xerostomia and SFR rates in the research subjects with HCMV positive saliva (p> 0.05). Conclusion: The presence of xerostomia-associated HCMV in saliva was elevated among HIV/AIDS patients. Further investigation is required to identify other gB genotypes that may be responsible for xerostomia and SFR changes in HIV/AIDS patients.

show abstract

Correlation between Xerostomia index, Clinical Oral Dryness Scale, and ESSPRI with different hyposalivation tests

Cited by 9 publications

References 27 publications

Association between xerostomia, oral and general health, and obesity in adults. A cross-sectional pilot study

Association between xerostomia, oral and general health, and obesity in adults. A cross-sectional pilot study

Correlation Between Clinical Oral Dryness Score and Salivary Flow Rates in Active and Passive Smokers

Analysis of the relationship between human cytomegalovirus DNA and gB-1 genotype in the saliva of HIV/AIDS patients with xerostomia and salivary flow rate

Contact Info

Product

Resources

About