Correlation between the Fetal Liver Length and Crown-Rump Length During the First Trimester Screening

Abstract

Objective: The aim of the present study was to determine the correlation between fetal liver length (FLL) at the 11+0-13+6 week of pregnancy and crown-rump length (CRL).Methods: Pregnant women (n=63) referring to the Başkent University Konya Hospital Obstetrics and Gynecology Clinic between January and March 2014 for first trimester screening were included in the study. Patients were excluded for the following reasons: two for type II DM, one for metabolic disease, and three because they refused to share their information. FLL was measured in patients at the 11+0-13+6 week of gestation and in those who had normal ultrasonographic findings. Exclusion criteria were as follows: nuchal translucency of ≥3.5 mm, antenatal first trimester combined test results of ≥1/250, reverse flow of the ductus venosus and tricuspid valve, absence of nasal bone (NB), and fetal malformation in second trimester. Fiftyseven women who fulfilled inclusion criteria were included in the study. Statistical Package for the Social Sciences version 15.0 (SPSS, Inc., Chicago, IL, USA) was used for statistical analysis. Descriptive statistics and Pearson's correlation test was used for correlation between FLL and CRL.Results: Mean age of patients was 28. 18±4.7 (19-39). Mean gravida and parity were 2.05±1.2 (1-6) and 1±0.8 (0-5), respectively. Mean gestational age was 12.4 weeks (min: 11.1 -max: 13.6), and mean FLL of the study group was 11.2±1.1 mm (8.2-13.7 mm). Mean NT was 1.1±0.3 (0.5-2.4) mm. In the present study, it was established that FLL was correlated with CRL (r (57): 0.840; p<0.001).Conclusion: This study showed that there was a significant, strong, positive correlation between FLL and CRL at the 11 th -13 th week of pregnancy. (JAREM 2015; 5: 60-3)

Morphometric study of the diaphragmatic surface of the liver in the human fetus

“…A reduction in the liver size can be caused by the intrauterine growth retardation. Contrariwise, an increase in the liver size is typical of erythroblastosis fetalis [13], falciform anemia, thalassemia or abnormalities in the transport of oxygen by hemoglobin Barts disease [9,14,15], maternal diabetes [3], intrauterine growth retardation, twin-to-twin transfusion syndrome (TTTS), and Down's syndrome [16]. According to Fleischer et al [17], the size of the liver is also a considerable clinical indicator in pregnancy complicated by Rh incompatibility.…”