Correlation between Short-Form 36 Scores and Neck Disability Index in Patients Undergoing Anterior Cervical Discectomy and Fusion

Ko, Sangbong; Choi, Won-Kee; Chae, Soo-Cheon; Kwon, Jaebum; Lee, Youngsik

doi:10.31616/asj.2018.12.4.691

Cited by 10 publications

(13 citation statements)

References 14 publications

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“…This, as well as the fact that NDI has been shown to sufficiently evaluate and represent a patient’s physical and mental quality of life, suggests that fusion status alone may not be a significant predictor of successful outcome. 24 Although our small sample sizes are small, we believe the rigorous patient selection, data collection, and postoperative follow-up monitoring afforded by the clinical trial creates high-quality data. Because the sample sizes were small, we avoid ascribing statistical significance to our findings and instead focus on descriptive reporting our experience with delayed union in ACDF due to the paucity of data available to clinicians for decision making in this difficult scenario.…”

Section: Discussionmentioning

confidence: 99%

Long-Term Radiographic and Functional Outcomes of Patients With Absence of Radiographic Union at 2 Years After Single-Level Anterior Cervical Discectomy and Fusion

Lee

Boody

Demeter

et al. 2019

Global Spine Journal

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Study Design: Retrospective radiographic investigation. Objective: To evaluate the long-term radiographic and functional outcomes of patients in whom there is absence of radiographic union at 2 years after single-level anterior cervical discectomy and fusion (ACDF). Methods: Thirty-one patients were evaluated at standard postoperative time intervals per index trial protocol. Plain film radiographic fusion criteria at the arthrodesis level was defined as interspinous motion (ISM) <1 mm with corresponding motion at a non-arthrodesed superjacent level ISM ≥4 mm. Radiographs and functional outcome measures were acquired at each follow-up visit. Delayed union was defined as lack of radiographic union by 24 months. Results: Nine patients demonstrated radiographic evidence of delayed radiographic union at 24 months. Of those 9 patients, 5 patients demonstrated evidence of union during the follow-up period to 72 months. Despite the absence of radiographic union based on our criteria, 3 of the 4 remaining patients reported remarkable improvements in pain scores and functional outcomes. Conclusions: The natural history of delayed union at 24 months after ACDF was still favorable despite the prolonged delay in union. The majority of patients (5 of 9) without radiographic union at 24 months did proceed to radiographic union by final follow-up. In addition, patients that did not meet our criteria for fusion maintained postoperative improvements in patient-reported outcome scores. In summary, our study patients undergoing a single-level ACDF with asymptomatic radiographic delayed union at 24 months can expect maintained improvements in postoperative patient-reported outcomes scores and can still progress to successful radiographic fusion.

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Section: Discussionmentioning

confidence: 99%

Long-Term Radiographic and Functional Outcomes of Patients With Absence of Radiographic Union at 2 Years After Single-Level Anterior Cervical Discectomy and Fusion

Lee

Boody

Demeter

et al. 2019

Global Spine Journal

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“…Although less common in the literature, direct correlation studies have reported similar results regarding both the significance and strength of relationship between neck disability and mental health PROMs. Specifically, both lumbar and cervical spine studies have evaluated the correlation of disability with Patient-Reported Outcomes Measurement Information System (PROMIS) metrics, 14,22 EuroQol-5D, 23 SF-36 MCS, 23,24 and HADS. 23 Although Purvis et al 22 conducted their study among lumbar spine patients, the authors were able to establish a strong correlation between PROMIS depression/anxiety and ODI.…”

Section: Discussionmentioning

confidence: 99%

Dual Role of Neck Disability Index in the Assessment of Quality of Life in Cervical Spine Patients

Elliot

Lynch

Geoghegan

et al. 2022

J Am Acad Orthop Surg

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Introduction:The Neck Disability Index (NDI) is a well-established measure for patients with cervical myelopathy, radiculopathy, or myeloradiculopathy. Few studies have examined the relationship between NDI and mental health outcomes after anterior cervical diskectomy and fusion (ACDF). Our study sets out to determine the possible correlations between NDI and mental health outcome measures after ACDF. Methods: A prospectively maintained surgical registry was retrospectively reviewed for elective ACDF procedures from December 2013 to December 2019. Demographic and perioperative characteristics were collected. Primary outcomes of interest were NDI, 12-Item Short Form Mental Component Summary (SF-12 MCS), and Patient Health Questionnaire-9 (PHQ-9). Outcomes were collected preoperatively and postoperatively (6 weeks, 12 weeks, 6 months, 1 year, and 2 years). Postoperative improvement for all outcomes was evaluated using a paired Student t-test. Correlations between NDI and mental health outcomes were evaluated using the Pearson correlation coefficient. Strength of association was determined using the following criteria: weak (0.1 # jrj , 0.3), moderate (0.3 # jrj , 0.5), and strong (jrj $ 0.5). Results: A total of 225 patients were included in this study. Most of the patients underwent a single-level procedure and had a spinal pathology of herniated nucleus pulposus. NDI demonstrated significant improvements through 2 years compared with preoperative values (all P , 0.001). Similarly, SF-12 MCS and PHQ-9 significantly improved through 1-year postoperatively (all P # 0.010) but was not maintained at 2 years (P = 0.835; P = 0.128). NDI demonstrated a significant but moderate correlation with SF-12 MCS at the preoperative time point, but a strong correlation was observed at all postoperative time points (all P # 0.001). A significant and strong

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“…While the improvement in PCS from baseline to 24 months was not statistically significant between ACDF and M6-C, the significantly higher PCS score at 24 months for M6-C vs ACDF could have been due to the significantly higher baseline PCS score for M6-C vs ACDF. This difference could potentially have influenced the NDI and thus the CCS as studies have shown a correlation between NDI and the PCS of the SF-36 [31]. However, the PS model did include NDI thus negating the PCS discrepancy and its potential influence on the CCS.…”

Section: Discussionmentioning

confidence: 99%

Prospective, multicenter clinical trial comparing M6-C compressible six degrees of freedom cervical disc with anterior cervical discectomy and fusion for the treatment of single-level degenerative cervical radiculopathy: 2-year results of an FDA investigational device exemption study

et al. 2021

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BACKGROUND CONTEXT: Various designs of total disk replacement (TDR) devices have been compared to anterior cervical discectomy and fusion (ACDF) with favorable outcomes in FDA-approved investigational device exemption trials. The design of M6-C with a compressible viscoelastic nuclear core and an annular structure is substantially different than prior designs and has previously demonstrated favorable kinematics and clinical outcomes in small case series. PURPOSE: To evaluate the safety and effectiveness of the novel M6-C compressible artificial cervical disk compared with ACDF for subjects with single-level degenerative cervical radiculopathy. STUDY DESIGN/SETTING: Prospective, multicenter, concurrently and historically controlled, FDA-approved investigational device exemption clinical trial. PATIENT SAMPLE: Subjects with one-level symptomatic degenerative cervical radiculopathy were enrolled and assigned to receive M6-C or ACDF. OUTCOME MEASURES: Pain and function (Neck Disability Index, VAS), quality of life (SF-36), safety, neurologic, and radiographic assessments of motion (both flexion extension and lateral bending) were performed. The primary clinical endpoint was composite clinical success (CCS) at 24 months. METHODS: Using propensity score subclassification to control for selection bias, 160 M6-C subjects were compared to a matched subset of 189 ACDF controls (46 concurrent and 143 historical controls). RESULTS: Both ACDF and M6-C subjects reported significant improvements in patient-reported outcomes at all time points over baseline. Overall SF-36 Physical Component Score and neck and arm pain scores were significantly improved for M6-C as compared to ACDF treatment. CCS and mean Neck Disability Index improvements were similar between M6-C and ACDF. Correspondingly, there were significantly fewer subjects that utilized pain medication or opioids following M6-C treatment at 24 months relative to baseline. Range of motion was maintained in subjects treated with M6-C. Subsequent surgical interventions, dysphagia rates, and serious adverse events were comparable between groups. CONCLUSIONS: M6-C treatment demonstrated both safety and effectiveness for the treatment of degenerative cervical radiculopathy. Treatment with M6-C demonstrated noninferiority for the primary endpoint, indicating a similar ability to achieve CCS at 24 months. However, for the secondary endpoints, M6-C subjects demonstrated significantly improved pain and function compared to ACDF subjects, while maintaining range of motion, improving quality of life, and decreasing analgesic and opioid usage at 2 years postoperatively relative to baseline.

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Correlation between Short-Form 36 Scores and Neck Disability Index in Patients Undergoing Anterior Cervical Discectomy and Fusion

Cited by 10 publications

References 14 publications

Long-Term Radiographic and Functional Outcomes of Patients With Absence of Radiographic Union at 2 Years After Single-Level Anterior Cervical Discectomy and Fusion

Long-Term Radiographic and Functional Outcomes of Patients With Absence of Radiographic Union at 2 Years After Single-Level Anterior Cervical Discectomy and Fusion

Dual Role of Neck Disability Index in the Assessment of Quality of Life in Cervical Spine Patients

Prospective, multicenter clinical trial comparing M6-C compressible six degrees of freedom cervical disc with anterior cervical discectomy and fusion for the treatment of single-level degenerative cervical radiculopathy: 2-year results of an FDA investigational device exemption study

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