Correlation between Scanning Laser Ophthalmoscope Microperimetry and Anatomic Abnormalities in Patients with Subfoveal Neovascularization

Tezel, Tongalp H.; Priore, Lucian V. Del; Flowers, Brian; Grosof, David H.; Benenson, Igor L.; Zamora, Rene L.; Kaplan, Henry J.

doi:10.1016/s0161-6420(96)30419-3

Cited by 56 publications

(31 citation statements)

References 32 publications

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“…Real-time correction of eye movements was measured with an auto tracking system. This allowed the assessment and quantification of therapy impact on fixation stability in ME patients [22,23,24,25,26,27]. According to our data, MRS documented a progressive improvement from baseline with the highest sensitivity found at the end of follow-up (6 months).…”

Section: Discussionsupporting

confidence: 53%

Exploring the Morphological and Functional Retinal Changes after Dexamethasone Intravitreal Implant (Ozurdex®) in Macular Edema due to Retinal Vein Occlusion

Parravano¹,

Oddone²,

Boccassini³

et al. 2014

Ophthalmic Res

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Purpose: To explore functional and morphological retinal changes 6 months after dexamethasone intravitreal implant (DEX implant) for the treatment of macular edema due to central or branch retinal vein occlusion (CRVO, BRVO). Procedures: In this prospective interventional case series patients underwent a complete ophthalmological examination at baseline and monthly, including best-corrected visual acuity (BCVA), spectral domain-optical coherence tomography and microperimetry. Fluorescein angiography was performed at baseline and at 4 months. All patients were treated with a DEX implant and retreated according to predefined criteria starting from month 4. Results: Sixteen patients (mean age 66 ± 13 years, 14 CRVO, 2 BRVO) were included. At 6 months mean retinal sensitivity improved from 9.7 ± 4.6 to 13.6 ± 5.4 dB (p < 0.0001) while mean BCVA improved from 52.4 ± 16.2 to 66.1 ± 16.6 (p < 0.0001). Mean central retinal thickness decreased from 708.3 ± 151.01 to 362.7 ± 177.4 μm (p < 0.0001); 56.2% of eyes were retreated at month 4. Conclusions: At 6 months DEX implant led to a significant improvement in retinal sensitivity and visual acuity associated with a reduction of retinal thickness in patients with macular edema due to retinal vein occlusion.

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Section: Discussionsupporting

confidence: 53%

Exploring the Morphological and Functional Retinal Changes after Dexamethasone Intravitreal Implant (Ozurdex®) in Macular Edema due to Retinal Vein Occlusion

Parravano¹,

Oddone²,

Boccassini³

et al. 2014

Ophthalmic Res

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“…Tezel et al also reported that the relative risk of an absolute scotoma is highest over areas of chorioretinal scars, RPE atrophy, subretinal hemorrhage, and neovascular We defined a significant enlargement of the ChRA as an increase of >20% in the area membranes [15]. Similarly, our eyes with an enlargement of the ChRA had significantly larger mCNVs at the baseline, a higher incidence of subretinal hemorrhage, and had a greater decrease of retinal sensitivity.…”

Section: Discussionmentioning

confidence: 75%

Factors associated with enlargement of chorioretinal atrophy after intravitreal bevacizumab for myopic choroidal neovascularization

Uemoto

Nakasato-Sonn

Kawagoe

et al. 2012

Graefes Arch Clin Exp Ophthalmol

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“…Olhos com exsudação têm, em média, pior sensibilidade que olhos sem exsudação. Outros estudos registraram a presença de escotomas relativos e absolutos nas áreas de neovascularização (6)(7)(8) . A duração dos sintomas e o tamanho da membrana neovascular foram associados à profundidade do escotoma (6) .…”

Section: Discussionunclassified

Avaliação da perimetria macular em pacientes com degeneração macular relacionada à idade por meio do oftalmoscópio de rastreamento a laser

Moraes¹,

Elsner²,

Kunze³

et al. 2007

Arq. Bras. Oftalmol.

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Correlation between Scanning Laser Ophthalmoscope Microperimetry and Anatomic Abnormalities in Patients with Subfoveal Neovascularization

Cited by 56 publications

References 32 publications

Exploring the Morphological and Functional Retinal Changes after Dexamethasone Intravitreal Implant (Ozurdex®) in Macular Edema due to Retinal Vein Occlusion

Exploring the Morphological and Functional Retinal Changes after Dexamethasone Intravitreal Implant (Ozurdex®) in Macular Edema due to Retinal Vein Occlusion

Factors associated with enlargement of chorioretinal atrophy after intravitreal bevacizumab for myopic choroidal neovascularization

Avaliação da perimetria macular em pacientes com degeneração macular relacionada à idade por meio do oftalmoscópio de rastreamento a laser

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