Correlation between Psychometric Tests and Mismatch Negativity in Preschool Children

Abstract

The objective was to determine whether mismatch negativity (MMN) is suitable to supplement subjective psychometric subtests of central hearing. We assessed 13 healthy children and 32 children with central auditory processing disorder (CAPD). Three different types of sound deviants were presented in a multi-deviant MMN design. At group level, the incidence of MMN was always higher in clinically diagnosed controls. Children with better results in the subtest Auditory Memory Span had a higher incidence of MMN. The controls also had peak latencies that occurred significantly earlier in frontal, central and temporal electrode sites. The area under the curve (AUC) displayed an asymmetric distribution in CAPD children, who tended to have a left-hemispheric dominance. AUC, peak latency, and the incidence of MMN reflected the discriminative ability of CAPD children. Hence, these characteristics could be used for investigating children with deficits in central hearing and can supplement psychometric tests.

Assessing Auditory Processing Disorders in Children with Developmental Dyslexia Using Auditory Cognitive Event-Related Potentials

“…Those potentials reflect semantic, cognitive and attention processes [11]. The results of our study showed that MMN and P300 were more frequent in healthy children than in those with dyslexia, similar to the findings of Sharma et al [14], Bauer et al [18] and Kraus et al [26]. Absent or slight responses of ERPs are thought to be indicative of hearing discrimination problems [1,17].…”

“…Several studies have shown that dyslexicchildren display changes in MMN and P300 waves suggesting impaired auditory processing [13,14]. MMN can serve as an early index of evaluation of developmental disorders (dyslexia, language disorders, auditory processing impairment) [15,16,17,18,19]. However, other examinations with ERPs have produced different results: dyslexic children did not differ in terms of MMN and P300 from healthy children [20,21,22].…”

Evaluation of Auditory Cortical Development in the Early Stages of Post Cochlear Implantation Using Mismatch Negativity Measurement

“…deviant stimulus vs. standard stimulus) in the auditory stimulus stream, and its largest amplitude is generally recorded over the fronto-central scalp areas at around 200ms post stimulus (13,14). It represents neurophysiologic changes in the brain's electrical activity in response to auditory discrimination (15), and therefore, it is considered to be an objective measurement to assess the auditory cortical function as well as central auditory processing function (16,17). Cheour et al (17) reported that the MMN presented in 8 of 12 full-term neonates (66.7%) and all of six 3-month-old infants (100%).…”

Using a multi‐feature paradigm to measure mismatch responses to minimal sound contrasts in children with cochlear implants and hearing aids

“…suggesting that the MMN paradigm has the potential to acquire information on auditory processing capabilities in addition to or instead of psychometric testing. The MMN has therefore also been used in studies on children with central auditory processing disorder (CAPD) (Bauer, Burger, Kummer, Lohscheller, Eysholdt & Doellinger, ), with or at risk of dyslexia (Bruder, Leppänen, Bartling, Csépe, Démonet & Schulte‐Körne, ; Lachmann, Berti, Kujala & Schröger, ; Lovio, Halttunen, Lyytinen, Näätänen & Kujala, ), learning impairment (Kraus, McGee, Carrell, Sharma & Nicol, ), Asperger's syndrome (Korpilahti, Jansson‐Verkasalo, Mattila et al ., ; Kujala,Lepistö, Nieminen‐von Wendt, Näätänen & Näätänen, ), and autism (Gomot, Giard, Roux, Barthélémy & Bruneau, ; Gomot, Blanc, Clery, Roux, Barthelemy & Bruneau, ; Lepistö et al ., ).…”