Correlation between pre‐pregnancy body mass index and maternal visceral adiposity with fetal biometry during the second trimester

Lopes, Karina R.M.; Souza, Alex Sandro Rolland; Figueirôa, José Natal; Alves, João Guilherme Bezerra

doi:10.1002/ijgo.12202

Cited by 13 publications

(11 citation statements)

References 24 publications

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“…Second trimester fetal biometry measurements are part of standard prenatal care in the United States and elsewhere, and accessing this data provides an additional window of susceptibility to examine the influence of environmental exposures. 50 While work in this area is limited to date, positive associations between maternal BMI and adiposity with fetal biometrics 50,51 as well as decreased estimated fetal weight with DEHP metabolites 25 have been reported. Metals (As, Ba, Pb) were negatively associated with femur length in this study.…”

Section: Discussionmentioning

confidence: 99%

First trimester maternal exposures to endocrine disrupting chemicals and metals and fetal size in the Michigan Mother–Infant Pairs study

Goodrich

Ingle

Domino

et al. 2019

J Dev Orig Health Dis

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Exposures to endocrine disrupting chemicals and metals are near ubiquitous worldwide, and their potential impact on children is a major public health concern. This pilot study was designed to characterize exposures to phthalates, phenols and metals among pregnant women in the first trimester, and to examine associations with fetal biometrics and birth weight. A total of 41 chemicals and elements were analyzed in urine from 56 mothers with full-term newborns from the Michigan Mother–Infant Pairs study. Bivariate analyses identified predictors of exposure biomarkers. Associations between birth weight, Fenton z-scores and second trimester fetal biometrics with toxicants were examined via multivariable linear regression. An average of 30 toxicants were detected in maternal urine. Fast food consumption was associated with several phthalate metabolites, phenols and metals, and canned food consumption with bisphenol F (P <0.05). Mono (3-carboxypropyl) phthalate was significantly associated with higher birth weight and Fenton z-score while the opposite was observed for bisphenol S. Estimated femur length from ultrasonography was significantly inversely associated with arsenic, barium and lead. While limited by sample size, this study is one of the first to evaluate birth outcomes with respect to emerging endocrine disrupting chemicals and to examine associations between toxicants and fetal biometrics. Exposure assessment was provided by the National Institute of Environmental Health Sciences’ Children’s Health Exposure Analysis Resource (NIEHS CHEAR), a resource available to children’s studies with the goal of combining data across cohorts in an effort to characterize the impact of toxicants on child health from birth and beyond.

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Section: Discussionmentioning

confidence: 99%

First trimester maternal exposures to endocrine disrupting chemicals and metals and fetal size in the Michigan Mother–Infant Pairs study

Goodrich

Ingle

Domino

et al. 2019

J Dev Orig Health Dis

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“…On the other hand, the measurement of the different compartments of abdominal fat via ultrasound provides an adequate estimate of central adiposity (22); however, the assessment of maternal central fat is not routinely performed in obstetric ultrasounds. The risk of adverse conditions caused by an excess of fat, particularly visceral fat, to the pregnant woman and fetus health is clearly consolidated in the literature (8,10,17,23,24), therefore, thus the precision and cost appraisal of different fat compartments is highly important to the population (25).…”

Section: Discussionmentioning

confidence: 99%

Anthropometrical measurements and maternal visceral fat during first half of pregnancy: a cross-sectional survey

Kretzer

Matos

Diemen

et al. 2020

Preprint

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Background Determining anthropometric measures that indicate different fat deposits can be useful to predict metabolic risk and set specific treatment goals, reducing negative consequences for maternal and fetal health. In cases where pre-gestational weight measure and subsequent body mass index (BMI) values cannot be determined, other anthropometric measurements may be ideal for measuring the nutritional status of pregnant women, especially in low- and middle-income countries. This study aims to identify which anthropometric measurements correlate better with the maternal fat deposits measured by ultrasound. Methods A cross-sectional study was conducted with pregnant women from the city of Porto Alegre (city), capital of Rio Grande do Sul (state), southern Brazil, from October 2016 until January 2018. Anthropometrical variables (weight, height, mid-upper arm circumference [MUAC], circumferences of calf and neck and triceps skinfolds [TSF] and subscapular skinfolds [SBSF]), and ultrasound variables (visceral adipose tissue [VAT] and total adipose tissue [TAT]) were collected. To verify the correlation of anthropometric and ultrasound measurements, a non-adjusted and adjusted Spearman correlation was used. The study was approved by the ethics committees. Results The age median of the 149 pregnant women was 25 years [21 - 31], pre-pregnancy BMI was 26.22kg/m² [22.16 – 31.21] and gestational age was 16.2 weeks [13.05 – 18.10]. The best measurements correlated with VAT and TAT were MUAC and SBSF, both of which showed a higher correlation than pre-pregnancy BMI. Conclusion It is possible to provide a practical and reliable estimate of VAT and TAT from the anthropometric evaluation (MUAC or SBSF) that is low cost, efficient and replicable in an outpatient clinic environment, especially in low- and middle-income countries.

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“…On the other hand, the measurement of the different compartments of abdominal fat via ultrasound provides an adequate estimate of central adiposity [ 22 ]; however, the assessment of maternal central fat is not routinely performed in obstetric ultrasounds. The risk of adverse conditions caused by an excess of fat, particularly visceral fat, to the pregnant woman and fetus health is clearly consolidated in the literature [ 8 , 10 , 17 , 23 , 24 ], therefore, thus the precision and cost appraisal of different fat compartments is highly important to the population [ 25 ].…”

Section: Discussionmentioning

confidence: 99%

Anthropometrical measurements and maternal visceral fat during first half of pregnancy: a cross-sectional survey

Kretzer¹,

Matos²,

Diemen³

et al. 2020

BMC Pregnancy Childbirth

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Background Determining anthropometric measures that indicate different fat deposits can be useful to predict metabolic risk and set specific treatment goals, reducing negative consequences for maternal and fetal health. In cases where pre-gestational weight measure and subsequent body mass index (BMI) values cannot be determined, other anthropometric measurements may be ideal for measuring the nutritional status of pregnant women, especially in low- and middle-income countries. This study aims to identify which anthropometric measurements correlate better with the maternal fat deposits measured by ultrasound. Methods A cross-sectional study was conducted with pregnant women from the city of Porto Alegre (city), capital of Rio Grande do Sul (state), southern Brazil, from October 2016 until January 2018. Anthropometrical variables (weight, height, mid-upper arm circumference [MUAC], circumferences of calf and neck and triceps skinfolds [TSF] and subscapular skinfolds [SBSF]), and ultrasound variables (visceral adipose tissue [VAT] and total adipose tissue [TAT]) were collected. To verify the correlation of anthropometric and ultrasound measurements, a non-adjusted and adjusted Spearman correlation was used. The study was approved by the ethics committees. Results The age median of the 149 pregnant women was 25 years [21–31], pre-pregnancy BMI was 26.22 kg/m² [22.16–31.21] and gestational age was 16.2 weeks [13.05–18.10]. The best measurements correlated with VAT and TAT were MUAC and SBSF, both of which showed a higher correlation than pre-pregnancy BMI. Conclusions It is possible to provide a practical and reliable estimate of VAT and TAT from the anthropometric evaluation (MUAC or SBSF) that is low cost, efficient and replicable in an outpatient clinic environment, especially in low- and middle-income countries.

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Correlation between pre‐pregnancy body mass index and maternal visceral adiposity with fetal biometry during the second trimester

Abstract: Maternal visceral adiposity, but not pre-pregnancy BMI, positively correlated with fetal biometry during the second trimester.

Cited by 13 publications

References 24 publications

First trimester maternal exposures to endocrine disrupting chemicals and metals and fetal size in the Michigan Mother–Infant Pairs study

First trimester maternal exposures to endocrine disrupting chemicals and metals and fetal size in the Michigan Mother–Infant Pairs study

Anthropometrical measurements and maternal visceral fat during first half of pregnancy: a cross-sectional survey

Anthropometrical measurements and maternal visceral fat during first half of pregnancy: a cross-sectional survey

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