Correlation between Fasting Blood Sugar Level, HbA1C Level and Serum Lipid Levels in Type 2 Diabetes Mellitus Patients

Dave, Mahesh; Gupta, Ajay Kumar; Patel, Puneet; Heernath, Heernath

doi:10.21276/ijcmr.2019.6.7.13

Cited by 10 publications

(5 citation statements)

References 11 publications

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“…We found that age group 20-30 years had 11, 30-40 years had 14, 40-50 years had 38, 50-60 years had 46 and >60 years had 25 patients. Dave et al, [9] in their cross sectional study conducted on 100 patients of diabetes mellitus, the fasting blood sugar (FBS) levels, HbA1C levels and serum lipid levels were performed and then correlated fasting blood sugar level with HbA1C levels and FBS and HbA1C with serum lipid levels. This study demonstrated that HbA1C level was increased in diabetics and it showed correlation with the status of control of diabetes.…”

Section: Discussionmentioning

confidence: 99%

To Assess Correlation of Fasting Blood Glucose, Hb1Ac and Serum Lipid Level in Type II Diabetes Mellitus Patients

Chauhan¹,

Agrawal²

2019

AJM

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Background: Diabetes Mellitus (DM) refers to a group of common metabolic disorder that share the phenotype of hyperglycaemia caused due to either deficiency of insulin secretion or insulin resistance. The present study was conducted to assess correlation of fasting blood glucose, Hb1Ac and type II DM in given adults. Subjects and Methods: The present study was conducted on 134 patients with type II diabetes mellitus (DM) of both genders. Patients were subjected to estimation of fasting and random blood glucose level. Modified method of Fluckiger and Winterhalter was used for estimation of glycosylated haemoglobin (HbA1C). Results: Out of 134 patients, males were 84 and females were 50. Age group 20-30 years had 11, 30-40 years had 14, 40-50 years had 38, 50-60 years had 46 and >60 years had 25 patients. The mean fasting blood glucose level in patients with good degree of control was 106.2, in fair was 164.4 and in poor was 208.2. Glycosylated hemoglobin level was good (6.74), fair (8.12) and poor (12.54). A positive correlation of fasting blood glucose and glycosylated hemoglobin level and serum cholesterol & glycosylated hemoglobin level (P< 0.05) was found. Conclusion: Authors found a positive correlation of fasting blood glucose and glycosylated hemoglobin level and serum cholesterol & glycosylated hemoglobin level in type II diabetes mellitus patients.

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Section: Discussionmentioning

confidence: 99%

To Assess Correlation of Fasting Blood Glucose, Hb1Ac and Serum Lipid Level in Type II Diabetes Mellitus Patients

Chauhan¹,

Agrawal²

2019

AJM

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“…Therefore, longer weeks of monitoring may be encouraged to ascertain the actual effect of the plant extract on hematological parameters. This result contradicts the report on the significant reduction of hematological parameters of alloxaninduced diabetics (Ogbera et al, 2009;Dave et al, 2019). Diabetes mellitus (DM) has been reported to be associated with cardiovascular morbidity and this may partly be explained by the abnormal lipid profile which is sometimes a feature of DM (Han et al, 2012).…”

Section: Resultsmentioning

confidence: 78%

Effect of a tropical plant (Hunteria umbellata) in the management of Streptozotocin induced Diabetes Mellitus and other physiological and biochemical functions in Wistar

Okolafor¹,

Ekhaise²

2021

Current Perspectives on Medicinal and Aromatic Plants (CUPMAP)

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Hunteria umbellata seeds, leaves and root are used as decoctions in Western and Southern part of Nigeria for the treatment of blood related ailments. The antidiabetic effect of Hunteria umbellata extracts (aqueous and methanol) on hematological, lipid profile and biochemical parameters in streptozotocin-induced diabetes in female Wistar rats was studied. The qualitative phytochemical screening of the seed extracts was determined using standard chemical methods. Twenty five Wistar rats weighing between 117 g and 170 g were shared into five groups of five animals per group for the physiological studies. All treatment groups were administered 500 mg/kg per body weight of H. umbellata extracts. Group I; normal control, Group II; negative or diabetic control, Group III; metformin + streptozotocin (STZ), Group IV; aqueous extract of H. umbellata + STZ and Group V; methanol extract of H. umbellata + STZ. Diabetes was induced with 55 mg/kg body weight STZ. Qualitative phytochemical screening of aqueous and methanol seed extracts of H. umbellata revealed the presence of secondary metabolites such as saponins, phytate, oxalate, anthraquinones, cyanogenic glycoside, phenols and alkaloids were recorded highest concentrations in both extracts. The hypoglycaemic studies of methanol extract revealed significant (p<0.005) reduction on the fasting blood glucose levels of experimental animals for Group V compared to moderate reduction in Group III. Group IV recorded increase in the blood glucose levels of Wistar rats. The haematological parameters were not significant (p>0.05) for all treatment groups. Group V recorded significance (p<0.05) amount of high density lipoproteins (HDL), total cholesterol (CHOL), triglyceride (TRIG) and low density lipoproteins (LDL) while CHOL was significant (p<0.05) for Group III. The biochemical parameters were within safe limit. The methanol extract of H. umbellata possesses the potentials for the managements of blood glucose levels and other physiological and biochemical functions compared to conventional drug (Metformin).

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“…Similar type of finding was obtained in a study conducted by Shrestha L et al 36 In another study conducted by Chauhan et al 37 found a positive correlation of FBG and HbA1c level. Similarly Dave M et al 38 observed that the level of HbA1c in diabetic patient is linearly correlated with FBG. While in another study conducted by Soonthornpun S et al 39 found PPBG correlated more strongly with HbA1c in comparison with FBG.…”

Section: Discussionmentioning

confidence: 79%

Evaluation of Serum Uric Acid, Glucose and Other Glycemic Parameter in Type Ii Diabetic Individuals

Dhungana

Pandeya

Pant

et al. 2022

JCMC

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Background: In spite of antioxidant property serum uric acid (SUA) has a positive association with blood glucose. SUA is considered as a strong and an independent risk factor for diabetes but low serum level of uric acid has been reported in the hyperglycemic state. Diabetes mellitus is a metabolic disorder of multiple etiologies resulting from defect in insulin action. So, aim of this study is to assess whether there is any change in SUA level and to establish whether there is any association with type II diabetes mellitus (DM) or not. Methods: A cross sectional study was conducted in 264 cases of DM. SUA, fasting blood glucose (FBG), post-prandial blood glucose (PPBG) and glycated hemoglobin (HbA1c) level were measured. Pearson’s correlation was employed to calculate the ‘r’ value by using SPSS version 15. Results: In our study prevalence of hyperuricemia was 18.5%. Mean SUA in male and female was 5.95 mg/dl and 5.54 mg/dl respectively in DM. HbA1c has positive correlation with FBG and PPBG (r value = 0.720 and 0.775, respectively p=<0.001), while SUA has negative correlation with HbA1c, FBG and PPBG (r value= -0.179, p =0.004, -0.070, p=0.257 and -0.078, p=-0.204 respectively.). Conclusions: SUA level is increased in DM. SUA was high among male and SUA initially increased when FBS and HbA1c increases then decreases as FBG and HbA1c level were further increased. SUA has negative correlation with FBG, PPBG and HbA1c, while HbA1c has a positive correlation with FBG and PPBG.

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Correlation between Fasting Blood Sugar Level, HbA1C Level and Serum Lipid Levels in Type 2 Diabetes Mellitus Patients

Cited by 10 publications

References 11 publications

To Assess Correlation of Fasting Blood Glucose, Hb1Ac and Serum Lipid Level in Type II Diabetes Mellitus Patients

To Assess Correlation of Fasting Blood Glucose, Hb1Ac and Serum Lipid Level in Type II Diabetes Mellitus Patients

Effect of a tropical plant (Hunteria umbellata) in the management of Streptozotocin induced Diabetes Mellitus and other physiological and biochemical functions in Wistar

Evaluation of Serum Uric Acid, Glucose and Other Glycemic Parameter in Type Ii Diabetic Individuals

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