Correlation between cVEMP and ABR for the Evaluation of Vestibular Migraine

Abstract

In this study, we aimed to determine the characteristics of the cVEMP and ABR responses of patients with VM and migraine in contrast to healthy controls. In this study, cVEMP and ABR changes during the VM attack period were compared with the cVEMP and OBJECTIVE: Vestibular migraine (VM) is a clinical condition characterized by temporal overlap between vestibular symptoms and migraine. In this study, we aimed to determine the changes in vestibular myogenic potential (cVEMP) and auditory brainstem response (ABR) in patients with VM and migraine. MATERIALS and METHODS:A total of 86 participants with no hearing loss or additional disease between the ages of 18 and 45 were enrolled in three different groups: group 1, VM; group 2, migraine without aura; and group 3, healthy controls. cVEMP and ABR were performed for all participants during attacks and attack-free periods. The differences between the right and left sides were calculated. RESULTS:There was no significant difference in cVEMP p13-n23 latencies between any of the groups. There were statistically significant differences related to cVEMP p13-n23 amplitudes between groups 1, 2, and 3. This significant difference originated from group 1 when compared with the other groups (p<0.05). When we compared the cVEMP results of patients with VM during attack and attack-free periods, a statistically significant decrease was determined in the p13-n23 amplitude values during the attack period (p<0.01). Additionally, when we compared group 1 and group 3, the wave V peak latencies in ABR were significantly prolonged in group 1 (p<0.05).CONCLUSION: cVEMP and ABR can be used as diagnostic criteria for patients with VM during attacks. Further studies with larger groups are needed to verify our findings.

Research on the Relationship Between Vestibular Migraine With/Without Cognitive Impairment and Brainstem Auditory Evoked Potential

“…In a longitudinal study by Sand et al (4), the intensity dependence of BAEP in migraine may not be a passive response to brainstem dysfunction. There were no changes in BAEP before the onset of migraine, and the peak latency of I-V wave and the peak latency of III-V wave increased after the onset of headache; the changes in BAEP seemed to reflect the slight effect of migraine symptoms on the serotonin brain stem pathway (27,28). In this study, patients in the migraine group had a longer V wave latency period than those in the control group.…”

Audiological Findings in Patients with Vestibular Migraine and Migraine: History of Migraine May Be a Cause of Low-Tone Sudden Sensorineural Hearing Loss

“…Bayazit et al [2001] found that 35% of the studied migraine cases had abnormal ABR, with elongation in the absolute wave latencies or elongation in both wave latencies and IPL. In the study by Sürmeli et al [2016], the authors observed that the wave V peak latency was prolonged significantly in the group of VM. In our study, we observed prolonged wave V latency and I-V IPL in the migraine group and prolonged I-V IPL in the VM group.…”

Cervical and Ocular Vestibular Evoked Myogenic Potentials in Migraine Patients

“…Our cVEMP and oVEMP findings were not correlated to any clinical symptom, except that cVEMP amplitude was statistically significant larger in both ears of migraine patients with aura compared to those without aura. However, Sürmeli et al [22] found that the cVEMP P13-N23 amplitudes in migraine patients with aura were significantly smaller than in patients without aura. In their χ 2 = 0.037, p = 1.000 †All migraine cases with abnormal cVEMP (n = 7) had delayed latency, even though they all had symmetrical amplitude.…”