Our results suggest a role of oxidative stress in the development of BPPV, through both calcium metabolism and the direct toxic effects of free oxygen radicals, including the triggering of apoptosis.
In our series of patients, we have seen no gross complications from fibrin glue usage. Fibrin glue can be readily used in septoplasty; it requires no special treatment, has an adequate hemostatic effect, and appears to promote the regeneration of mucociliary activity of the injured mucosa postoperatively.
Transoral robotic supraglottic laryngectomy for supraglottic laryngeal cancer is an oncologically safe and functional procedure with better results when compared to conventional open surgery.
Although primary acquired NLD obstruction seems to be an ophthalmologic problem, rhinologic problems have great importance in etiology. Detailed endoscopic examination and preoperative paranasal sinus computed tomography will reveal the possible role of nasal and paranasal structures adjacent to lacrimal sac in etiology of NLD obstruction. This will be effective both on conservative treatment and postoperative success in patients scheduled for surgery.
The aim of this study was to evaluate the correlation of the systemic immune-inflammation index (SII) and neutrophil-to-lymphocyte ratio (NLR) with histopathological findings in patients with tongue squamous cell carcinoma (SCC). Methods: 33 patients with tongue SCC were enrolled. The SII (NxP/L) based on neutrophil (N), lymphocyte (L), and platelet (P) counts was used as a biomarker. The results were compared with those of 34 healthy individuals. In addition, the correlation of NLR and SII with the presence of perineural and lymphovascular invasion, extranodal extension, and pathological differentiation degree was studied. Results: Patients with tongue SCC had significantly higher NLR and SII than healthy subjects (p=0.027, p=0.023 respectively). Receiver operating characteristic curve analysis indicated optimal NLR and SII cutoff values to be 1.98 and 477.30, respectively. Comparisons of perineural invasion, lymphovascular invasion, and extranodal extension with SII were statistically significant (p=0.044, p=0.012, p=0.022). Nevertheless, NLR only correlated with extranodal extension (p=0.003). No significant correlation was observed between the pathological degree of tongue SCC and NLR and SII. Discussion and Conclusion: SII is a novel, inexpensive, and useful biomarker that has a predictive value in the disease progression of patients with tongue SCC. High levels of pretreatment SII indicate a probable high risk of perineural and/or lymphovascular invasion and extranodal extension.
Mastoid volume values in the chronic otitis media group were significantly smaller when compared with those of a healthy group (p < 0.05). In healthy and diseased mastoid groups, there were no significant differences between groups when we assessed Henle spine-sigmoid sinus (HS-SS) distances. There was a significant correlation (p = 0.001) in both the groups when we compared mastoid volume values with HS-SS distances. There was ossicular discontinuity in two cases and in one patient tegmen tympani was not intact in diseased ears.
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