Correlation between coronary artery disease severity, left ventricular mass index and carotid intima media thickness, assessed by radio-frequency

Ciccone, Marco Matteo; Scicchitano, Pietro; Zito, Annapaola; Agati, Luciano; Gesualdo, Michele; Mandolesi, Sandro; Carbonara, Roberta; Ciciarello, Francesco; Fedele, Francesco

doi:10.1186/1476-7120-9-32

Cited by 33 publications

(31 citation statements)

References 34 publications

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“…Three points were measured on 1 scan, which was synchronized with the R wave peaks on the ECG to avoid possible errors resulting from variable arterial compliance. Mean carotid IMT was calculated from 6 measurements on 2 scans [30,31].…”

Section: Imt and Fmd Measurementmentioning

confidence: 99%

Coronary Microvascular function, Peripheral Endothelial Function and Carotid IMT in beta-thalassemia minor

Güllü

Çalışkan

et al. 2013

Thrombosis Research

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Section: Imt and Fmd Measurementmentioning

confidence: 99%

Coronary Microvascular function, Peripheral Endothelial Function and Carotid IMT in beta-thalassemia minor

Güllü

Çalışkan

et al. 2013

Thrombosis Research

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“…LVMI may be related to the intima-media thickness of the common carotid artery, a validated marker of systemic atherosclerosis process. 22 In a cohort study, LVH has been associated with the prevalence and severity of atherosclerosis, such as valve calcification independent of hypertension. 23 Renin-angiotensin system modulators are likely effective in preventing the progression of atherosclerosis of the carotid artery 24 and in reversing LVH.…”

Section: Ras and Lvhmentioning

confidence: 99%

Difference in Left Ventricular Mass Index Between Hypertensive Patients With and Without Renal Artery Stenosis by Propensity Score Analysis

Hoshida¹,

Shinoda²,

Inui³

et al. 2014

J of Clinical Hypertension

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3This study aimed to define the difference in cardiac hypertrophy between hypertensive patients with and without renal artery stenosis (RAS). When cardiac ultrasonographic examination was performed in 971 consecutive hypertensive outpatients, renal peak systolic velocity (PSV) was examined. Compared with patients without RAS, those with RAS (PSV ≥180 cm/s, 4.1%) were significantly older and included a higher proportion of male patients and had a higher left ventricular mass index (LVMI). A stratified analysis in the selected 120 patients showed that the LVMI was significantly higher in patients with RAS than in those without RAS for each confounding factor such as age and blood pressure. RAS was independently associated with a higher LVMI on propensity score analysis and multivariate analysis. Thus, the difference in LVMI between hypertensive patients with and without RAS was confirmed, irrespective of age and blood pressure, by stratified propensity score analysis and multivariate regression analysis. J Clin Hypertens (Greenwich). 2014;16:606-611. ª 2014 Wiley Periodicals, Inc.Renal artery stenosis (RAS) is found in 1% to 6% of all patients with hypertension and in 10% to 30% of hypertensive patients with known or suspected systemic atherosclerotic disease. [1][2][3][4][5] In the presence of RAS, the renin-angiotensin system is stimulated, 6 and angiotensin II has been shown to induce left ventricular hypertrophy (LVH). 7 In contrast, LVH increases the risk of systemic atherosclerotic disease such as RAS and predicts the incidence of cardiovascular events. A previous study revealed that the extent of LVH did not differ significantly between patients with renovascular hypertension and essential hypertension, 8 although the population consisted of younger patients in their 40s. Blood pressure (BP) may be a strong determinant of LVH, irrespective of the cause of hypertension. However, the prevalence of RAS is increasing because of recent advances in imaging techniques, the presence of an aging population, and an increasing prevalence of metabolic syndrome.9 At present, in this aging era, the prevalence of RAS and the differences in the extent of LVH between hypertensive populations with and without RAS and the involvement of age and BP in the differences are unclear.In a recent retrospective study, propensity scorebased analysis was performed to avoid baseline imbalances. There are 4 common techniques that use the propensity score to make adjustments for covariates before calculation of the indexed effect: (1) inverseprobability weighting, (2) matching, (3) stratification, and (4) regression adjustment. [10][11][12] The present study aimed to define the characteristics of RAS and investigate the differences in RAS-associated left ventricular mass index (LVMI) in hypertensive patients by a propensity score analysis and multivariate regression analysis. As we were interested in estimating the average effect of confounders such as age and BP on LVMI, rather than the average effect for the patients, with a greater red...

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“…These effects of statins take place before lipid changes [7,8]. Clopidogrel, a pro-drug largely prescribed for patients undergoing stent implantation, is metabolized in the liver via cytochrome P450 (CYP2C19 and CYP3A4) to form an active metabolite that inhibits the P2Y(12) ADP platelet receptor [9,10]. Rosuvastatin is partially metabolized by CYP2C9 and CYP2C19 [11].…”

mentioning

confidence: 99%

“…Three configurations could be outlined: kinking (ICA angulation b90°); tortuosity (S-or C-shaped carotid, angulation N90°); coiling (elongated carotid forming N1 loops on transverse axis) [1,2], which may be linked to age, atherosclerosis risk factors [3][4][5][6][7][8], embryogenetic defects [7] or metaplastic transformation of arterial tunica media [8]. Ischemic dilated cardiomyopathy (IDCM) is associated to increased common carotid intima-media thickness (CCA-IMT) and atherosclerosis process [9][10][11]; nevertheless, non ischemic dilated cardiomyopathy (NIDCM) is linked to carotid hyper-echogenicity [12]. The study's aim was to investigate a possible relationship between DCs and NIDCM.…”

mentioning

confidence: 99%

Dolichocarotids and dilated cardiomyopathy: Is there a relationship?

Ciccone

Scicchitano

Palumbo

et al. 2012

International Journal of Cardiology

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Correlation between coronary artery disease severity, left ventricular mass index and carotid intima media thickness, assessed by radio-frequency

Cited by 33 publications

References 34 publications

Coronary Microvascular function, Peripheral Endothelial Function and Carotid IMT in beta-thalassemia minor

Coronary Microvascular function, Peripheral Endothelial Function and Carotid IMT in beta-thalassemia minor

Difference in Left Ventricular Mass Index Between Hypertensive Patients With and Without Renal Artery Stenosis by Propensity Score Analysis

Dolichocarotids and dilated cardiomyopathy: Is there a relationship?

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