Correlation between corneal and contact lens deformation with changes in intraocular pressure for wearable monitoring systems

Campigotto, Angelica; Campbell, Robert J.; Lai, Yongjun

doi:10.1038/s41433-022-02285-y

Cited by 1 publication

(2 citation statements)

References 25 publications

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“…In a recent study, Campigotto et al used 12 cadaveric eyes and varied the IOP from 10 to 36 mmHg, as expected in the case of glaucoma [61]. The authors observed that the deformation from the curvature of the eye-as it varies within the specified range-was significant enough to be captured and mimicked by a silicone contact lens overlying the eye.…”

Section: Engineering Of Contact-lens-based Sensorsmentioning

confidence: 98%

“…Contact-lens-based sensors (CLBS) for monitoring intraocular pressure (IOP) can be categorized into three main types based on their sensing principles, namely, optical, microfluidic, and electrical sensors. Regardless of their categorization, however, one central concept is fundamental to the operation of all CLBS [61]. This concept is the relationship between the IOP and the corneal curvature.…”

Section: Engineering Of Contact-lens-based Sensorsmentioning

confidence: 99%

See 1 more Smart Citation

Advancements in Wearable and Implantable Intraocular Pressure Biosensors for Ophthalmology: A Comprehensive Review

Wu,

Mina,

Carbonneau

et al. 2023

Micromachines

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Glaucoma, marked by its intricate association with intraocular pressure (IOP), stands as a predominant cause of non-reversible vision loss. In this review, the physiological relevance of IOP is detailed, alongside its potential pathological consequences. The review further delves into innovative engineering solutions for IOP monitoring, highlighting the latest advancements in wearable and implantable sensors and their potential in enhancing glaucoma management. These technological innovations are interwoven with clinical practice, underscoring their real-world applications, patient-centered strategies, and the prospects for future development in IOP control. By synthesizing theoretical concepts, technological innovations, and practical clinical insights, this review contributes a cohesive and comprehensive perspective on the IOP biosensor’s role in glaucoma, serving as a reference for ophthalmological researchers, clinicians, and professionals.

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Section: Engineering Of Contact-lens-based Sensorsmentioning

confidence: 98%

Section: Engineering Of Contact-lens-based Sensorsmentioning

confidence: 99%