Correlation between central corneal thickness and myopia in Taiwan

Abstract

The aim of the study was to explore the correlation between central corneal thickness (CCT) and the degree of myopia in Taiwanese adults. A total of 528 individuals were enrolled to undergo myopic laser refractive surgery from January 2004 to December 2006. Preoperative CCT was measured using the Orbscan corneal topography system and refractive status was determined by cycloplegic spherical equivalent. The relationship between CCT and refractive error was investigated by interindividual and intraindividual analyses. Participants had a mean age of 34.8 ± 7.3 years, and 79.9% were female. The mean refractive error was -7.27 ± 2.96 diopters and the mean CCT measurement was 560 ± 35 μm. CCT revealed that there was no association with age. However, CCT was significantly (p = 0.012) less in females than in males. The CCT also showed no significant association with refractive error (p = 0.49). Among the 67 participants with myopic anisometropia, the mean difference between both eyes was 3.09 ± 1.06 diopters. There was no association between the intereye CCT difference and refractive error (p = 0.57). The results remained the same after adjusting for age and sex. In conclusion, there was no correlation between CCT and the degree of myopia among adults in Taiwan. These data might contribute to the ongoing discussion about the role of CCT in the higher incidence of development and progression of glaucoma in myopic individuals.

Correlation between refractive state, corneal thickness, and keratometry in ametropic patients

“…25 Others, however, found a negative correlation 26 or no correlation. [27][28][29] It seems as though the studies with very large cohorts (as opposed to those with smaller cohorts) identified small magnitudes of correlation between refractive error and corneal thickness which, again, are of unclear clinical significance.…”

Central Corneal Thickness: Important Considerate in Ophthalmic Clinic

“…Yi-Chun Chen et al [22] observed that CCT has no association with age while its significance was less in females than in males. It also showed that CCT has no significant association with refractive error.…”

The relation between central corneal thickness, axial length and myopia among a sample of patients in Erbil

“…This finding agrees with the most of the earlier studies. [12][13][14][15][16][17][18][19][20][21][22] According to such findings, we consider that if the stretching process is actually active, the thinning is likely to be restricted only to the sclera and the cornea is not involved. The current study has the limitation that we measured CCT in the morning and there are studies that investigated the diurnal changes of corneal thickness with various techniques.…”

“…7 Others have found that CCT is thinner in myopic eyes, [8][9][10][11] while some studies have reported no association between central corneal thickness and degree of myopia. [12][13][14][15][16][17][18][19][20][21][22] The results of this study will help the refractive surgeons how to evaluate and choose the type of the refractive surgeries like the laser in situ keratomileusis and photorefractive keratectomy for myopic patients and to assess the risk of postoperative complications. The purpose of this study was to determine the correlation between central corneal thickness, axial length and myopia.…”