Abstract:Background: Acute myeloid leukaemia is considered one of the heterogeneous hematologic cancers that have a range of therapeutic modalities, genetic abnormalities, and prognoses. AML treatment that is effective is still difficult. Increasing anti-tumor response by inhibiting immunological checkpoints is an appealing approach for leukaemia treatments. An essential immunological checkpoint known as CD200 is the ligand for CD200 receptor (CD200R), which is present on myeloid and lymphoid cells. CD200R limits anti-… Show more
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