Correlation between Arterial Blood Gas Analysis and Outcome in patients with severe head trauma

Bazzazi, Amirmohammad; Hasanloei, Mohammad Amin Valizade; Mahoori, Alireza; Gholamnejad, Mahdia; Tarverdipour, Habibeh

doi:10.5505/tjtes.2014.57089

Cited by 7 publications

(6 citation statements)

References 12 publications

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“…In a study involving severe head trauma, no signi cant statistical result was found in patients with normal PO2 levels in ABG measured in the emergency department, even if they showed a better prognosis [27].…”

Section: Discussionmentioning

confidence: 86%

The Relationship of Blood Gas Values With Prognosis in Pediatric Patients With Severe Head Trauma

Kayabas

Şahin

2021

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Purpose:Severe head traumas in the childhood age group has an important place in terms of mortality and morbidity among all traumas. Our aim in this study is to consider the relationship between the severity of severe head trauma and arterial blood gas (ABG) parameter levels in children.Methods:In our study, patients with head trauma, intubation and Glascow Coma Score (GCS) ≤ 8 were retrospectively analyzed. Showing homogeneous distribution; Independent sample T test was used for pH, PCO2 and base extract (BE) parameters, and Mann Whitney U test was used for PO2 and lactate parameters not showing homogeneous distribution. ROC analysis was done.Results:Of the 48 patients included in the study, 17 died while lying in the intensive care unit. There was no statistical difference when looking at the relationship between age, gender, surgical methods and mortality of the patients (p> 0.05). The relationship of patients with acidosis, hypercapnia and hyperlactatemia in ABG with mortality was statistically significant (p˂0.05). No statistically significant difference was found between surviving and deceased in ABG of patients regarding BE and hypoxia (p= 0.075; 0.175). there was a statistically significant difference between the mean values of PCO2 and lactate which are among the quantitative values and those who survived and died (p <0.05).Conclusion: Acidosis, the presence hypercapnia and hyperlactatemia were found to be associated with mortality in children with severe head trauma in ABG analysis. This study shows that PCO2 and lactate levels in ABG can be a biomarker in determining the prognosis in pediatric patients with traumatic brain injury (TBI).

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Section: Discussionmentioning

confidence: 86%

The Relationship of Blood Gas Values With Prognosis in Pediatric Patients With Severe Head Trauma

Kayabas

Şahin

2021

Preprint

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“…Most critically ill patients have a central venous catheter and the central venous oxygen saturation (SCVO 2 ) has been used as an alternative to the SMVO 2 . A few studies were conducted for hemodynamic monitoring with SCVO 2 , but their results in various situations were different (2, 15, 16). Based on these data, the surviving sepsis campaign has recommended achieving a SMVO 2 level of 65% or a SCVO 2 level of 70% in septic shock patients.…”

Section: Discussionmentioning

confidence: 99%

The Relationship between Arterial and Central Venous Blood Gases Values in Patients Undergoing Mechanical Ventilation after Cardiac Surgery

et al. 2018

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BackgroundThe most straightforward method of ascertaining arterial PO2, PCO2, and other components of blood gas is to measure them directly from a blood sample. In situations in which arterial puncture cannot be achieved or may be technically difficult, the venous blood sample can be used.MethodsIn a prospective analytical study, 80 patients undergoing mechanical ventilation after open-heart surgery in the intensive care unit were evaluated. Simultaneous, matched arterial and central venous blood gas samples were taken from radial artery line and central vein, respectively, when the ABG (arterial blood gases) assessment was needed. Arterial and central venous blood samples were analyzed and data were expressed as mean and ± SD.ResultsThe Pearson correlation coefficient for pH, PCO2, HCO3, and SatO2 was 0.898, 0.940, 0.840, and 0.567, respectively. There was a significant correlation between arterial and central venous values of pH, PCO2, and HCO3 (P < 0.0001). The mean difference between arterial and central venous PCO2 was -2.44 ± 2.6 mmHg, and the mean venous pH value was only 0.021 ± 0.037 units lower than the mean arterial value. In addition, the calculated mean bicarbonate concentration in venous blood was only about 0.06 ± 1.5 mEq.L higher than the mean arterial value.ConclusionsThe central venous PCO2, pH, and HCO3 measured during mechanical ventilation in the intensive care unit approximate arterial values closely enough to permit the estimation of the adequacy of ventilation and acid-base status. The central venous Sat O2 does not reliably parallel the arterial Sat O2. In conclusion, venous blood sampling can potentially reduce the requirement for ABG sampling in special situations.

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“…Leukocytosis is an increase in the number of white blood cell (WBC) in the bloodstream. [19][20][21] The normal WBC count is 1 to 4 WBC per microliter (LCM). 22 An increase in the number of WBC is called leukocytosis.…”

Section: Introductionmentioning

confidence: 99%

Diagnostic and predictive value of white blood cell count, erythrocyte sedimentation rate, and coagulation tests in patients with blunt head trauma

et al. 2020

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Introduction: Head trauma is the third leading cause of death and one of the most common causes of referral to the emergency department. Prognosis in these patients identifies individuals at higher risk and provides them with faster and more complete treatment, so it is of particular importance. The aim of this study is to evaluate the diagnostic and predictive value of white blood cell (WBC) count, erythrocyte sedimentation rate (ESR), and coagulation tests in the outcome of patients with blunt head trauma. Methods: In this retrospective study, 91 patients referred to the emergency department of Imam Reza hospital of Tabriz, with a complaint of DAI type of blunt head trauma, were enrolled in a complete and sequential study during the first six months of the year 2017. The patientswere divided into two groups according to good or poor prognosis and their association with leukocytosis status and other paraclinical factors at the baseline. Results: The final outcome in high consciousness group was 13.3% need for intubation,26.7% need for surgery, 50% improvement without complications, and 10% mortality. In the low consciousness group, 16.7% required intubation, 20.0% required surgery, 10% had no complications, and 53.3% experienced mortality. The significance level of the chi-squaretest was 0.001. Independent t test results showed that the WBC and ESR values in the lowconsciousness group were significantly higher than the high consciousness group. But the international normalized ratio (INR) in the high consciousness group was significantly higher than the low consciousness group (P<0.05). Conclusion: There is a significant relationship between severity of injury and leukocytosis, ESRelevation, and related coagulopathy after major trauma.

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Correlation between Arterial Blood Gas Analysis and Outcome in patients with severe head trauma

Cited by 7 publications

References 12 publications

The Relationship of Blood Gas Values With Prognosis in Pediatric Patients With Severe Head Trauma

The Relationship of Blood Gas Values With Prognosis in Pediatric Patients With Severe Head Trauma

The Relationship between Arterial and Central Venous Blood Gases Values in Patients Undergoing Mechanical Ventilation after Cardiac Surgery

Diagnostic and predictive value of white blood cell count, erythrocyte sedimentation rate, and coagulation tests in patients with blunt head trauma

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