The Relationship between Arterial and Central Venous Blood Gases Values in Patients Undergoing Mechanical Ventilation after Cardiac Surgery

Hassanloei, Mohammadamin Valizad; Mahoori, Alireza; Karami, Nazli; Sina, Venus

doi:10.5812/aapm.74243

Cited by 4 publications

(2 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Among studies on patients with any clinical contexts (metabolic, respiratory, or complex acid-base disorders), a considerable heterogenicity in the results was seen [13][14][15][16][17][18][19][20][21][22][23][24][25][26][27][28]. Bohloli [16] suggested using single regression prediction models to predict arterial PCO 2 and HCO 3 , to replace ABG with PVBG.…”

Section: Discussionmentioning

confidence: 99%

“…One study conducted on patients undergoing mechanical ventilation after open-heart surgery in the ICU revealed that central venous saturation O 2 did not consistently predict arterial saturation O 2 . Nonetheless, the study authors suggested substituting ABG analysis with CVBG analysis in specific situations [ 15 ]. Malinoski et al [ 14 ] compared ABG and CVBG values of pH, pCO 2 , and base excess but not those of HCO 3 and pO 2 in mechanically ventilated trauma patients admitted to ICU.…”

Section: Reviewmentioning

confidence: 99%

See 1 more Smart Citation

Arterial Versus Venous Blood Gas Analysis Comparisons, Appropriateness, and Alternatives in Different Acid/Base Clinical Settings: A Systematic Review

Saberian¹,

Sharif²,

Aarabi³

et al. 2023

Cureus

View full text Add to dashboard Cite

Arterial blood gases (ABGs) are routinely done in critical clinical settings to ascertain acid-base status. Due to difficulties and the potential side effects following arterial blood sampling, much research has been done to find the possibility of using venous samples as an alternative. However, this comparison needs to be evaluated in various contexts. Hence, this systematic review aims to explore the differences, appropriateness, and alternatives of arterial versus venous blood gas (VBG) analysis in different acid-base states. A comprehensive literature search was conducted through electronic databases using the terms “ABG,” “VBG,” “Arterial Blood Gas,” “Venous Blood Gas,” and “Gas analysis.” Studies' qualities were assessed by using Newcastle - Ottawa Quality Assessment Scale. Of 531 articles, 22 were included in the study after title, abstract, and full-text screening. Based on the Newcastle - Ottawa Quality Assessment Scale, 23% of the studies had good quality (score ≥ 7), 77% fair quality (score 2-6), and none of the studies had poor quality (score ≤ 1). Moreover, 22.5% of the included articles found a strong correlation between ABG and VBG. 73% compared arterial and VBG parameters among patients with any clinical contexts, 22.5% in respiratory diseases, and 4.5% in metabolic conditions, and their results had a significant disparity. There was a considerable discrepancy among authors about the appropriateness and utilization of VBG as an alternative to ABG. Our findings suggest that those studies did not consider physiological differences between venous and arterial blood values and obviated the significance of sampling procedures.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Reviewmentioning

confidence: 99%

Arterial Versus Venous Blood Gas Analysis Comparisons, Appropriateness, and Alternatives in Different Acid/Base Clinical Settings: A Systematic Review

Saberian¹,

Sharif²,

Aarabi³

et al. 2023

Cureus

View full text Add to dashboard Cite

show abstract

Pitfalls in the diagnosis and management of acid–base disorders in humans: a laboratory medicine perspective

Carlton,

Shipman

2024

J Clin Pathol

View full text Add to dashboard Cite

Diagnostic errors affect patient management, and as blood gas analysis is mainly performed without the laboratory, users must be aware of the potential pitfalls. The aim was to provide a summary of common issues users should be aware of.A narrative review was performed using online databases such as PubMed, Google Scholar and reference lists of identified papers. Language was limited to English.Errors can be pre-analytical, analytical or post-analytical. Samples should be analysed within 15 min and kept at room temperature and taken at least 15–30 min after changes to inspired oxygen and ventilator settings, for accurate oxygen measurement. Plastic syringes are more oxygen permeable if chilled. Currently, analysers run arterial, venous, capillary and intraosseous samples, but variations in reference intervals may not be appreciated or reported. Analytical issues can arise from interference secondary to drugs, such as spurious hyperchloraemia with salicylate and hyperlactataemia with ethylene glycol, or pathology, such as spurious hypoxaemia with leucocytosis and alkalosis in hypoalbuminaemia. Interpretation is complicated by result adjustment, for example, temperature (alpha-stat adjustment may overestimate partial pressure of carbon dioxide (pCO2) in hypothermia, for example), and inappropriate reference intervals, for example, in pregnancy bicarbonate, and pCO2ranges should be lowered.Lack of appreciation for patient-specific and circumstance-specific reference intervals, including extremes of age and altitude, and transformation of measurements to standard conditions can lead to inappropriate assumptions. It is vitally important for users to optimise specimen collection, appreciate the analytical methods and understand when reference intervals are applicable to their specimen type, clinical question or patient.

show abstract

The Effect of Heparin Concentration on Results of Venous Blood Gas of Patients admitted to Cardiac Intensive Care Unit: A double-blind clinical Trial

Hadipourzadeh¹,

Lakziyan²,

Shabani³

et al. 2022

BioMedicine

View full text Add to dashboard Cite

Background The aim of the present study was to investigate the effect of heparin (1000 IU/mL) in the blood sample on the results of venous blood gases of patients admitted to the cardiac intensive care unit. Materials and methods The present double-blind randomized clinical trial study was performed on 282 samples from 141 patients admitted to the cardiac intensive care unit. Insulin syringes with heparin (1000 IU/mL) and heparin (5000 IU/mL) and 1 cc of blood sample were taken from the peripheral vein, then distributed in two syringes and given to the analyzer. Results In the present study, the mean age of the samples was 49.96 ± 9.58. There was a statistically significant difference between the two groups in terms of values of partial pressure of carbon dioxide (PCO2) (P < 0.001), partial pressure of oxygen (PaO2) (P < 0.001), blood oxygen saturation (P < 0.001), bicarbonate ion (P < 0.001), excess base (P < 0.001), hemoglobin (P < 0.001), calcium (P < 0.001), potassium (P < 0.001), and sodium (P < 0.001) in the two groups. Conclusion Overall, heparin (1000 IU/mL) led to a less disruption in the results of venous blood gases, and since it has not significantly increased the risk of clots, it is recommended to be used for venous blood gas sampling.

show abstract

The Relationship between Arterial and Central Venous Blood Gases Values in Patients Undergoing Mechanical Ventilation after Cardiac Surgery

Cited by 4 publications

References 18 publications

Arterial Versus Venous Blood Gas Analysis Comparisons, Appropriateness, and Alternatives in Different Acid/Base Clinical Settings: A Systematic Review

Arterial Versus Venous Blood Gas Analysis Comparisons, Appropriateness, and Alternatives in Different Acid/Base Clinical Settings: A Systematic Review

Pitfalls in the diagnosis and management of acid–base disorders in humans: a laboratory medicine perspective

The Effect of Heparin Concentration on Results of Venous Blood Gas of Patients admitted to Cardiac Intensive Care Unit: A double-blind clinical Trial

Contact Info

Product

Resources

About