Correlating Median Nerve Cross-sectional Area With Nerve Conduction Studies

Pulikkottil, Benson J.; Schub, Micah; Kadow, Tiffany R.; Wang, William Yang; Fowler, John R.

doi:10.1016/j.jhsa.2016.08.018

Cited by 20 publications

(14 citation statements)

References 12 publications

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“…The MNCSA is also a useful morphological parameter for the evaluation of CTS. Many previous researches have used image modalities and focused on a quantitative analysis of the MNCSA in the carpal tunnel, and reported that MNCSA measurements could be useful in assessing CTS [4,9,11,12,26,27]. Ikeda et al [4] demonstrated that CTMRI is a valuable examination for imaging the crosssectional area of the median nerve and has potential as a diagnostic modality for CTS.…”

Section: Discussionmentioning

confidence: 99%

The prognostic value of median nerve thickness in diagnosing carpal tunnel syndrome using magnetic resonance imaging: a pilot study

et al. 2020

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Section: Discussionmentioning

confidence: 99%

The prognostic value of median nerve thickness in diagnosing carpal tunnel syndrome using magnetic resonance imaging: a pilot study

et al. 2020

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“…Ultrasound findings, particularly the median nerve cross‐sectional area (CSA), are significantly correlated with NCS. A moderate to very strong relationship has been reported between median CSA and severity classification determined by NCS 21,25,26,28 . Using median nerve CSAs to create nine diagnostic categories, Ziswiler et al 23 found a strong negative association between CSA and sensory nerve conduction velocity ( ρ = −0.65, p < .001), where conduction velocity decreased by 2.0 m/s per mm 2 increase in CSA.…”

Section: Introductionmentioning

confidence: 99%

“…A moderate to very strong relationship has been reported between median CSA and severity classification determined by NCS. 21,25,26,28 Using median nerve CSAs to create nine diagnostic categories, Ziswiler et al 23 found a strong negative association between CSA and sensory nerve conduction velocity (ρ = −0.65, p < .001), where conduction velocity decreased by 2.0 m/s per mm 2 increase in CSA. A moderate positive correlation was also observed between CSA and distal motor latency (ρ = 0.50, p < .001).…”

mentioning

confidence: 99%

Ultrasound examination predicts 6‐month progression in carpal tunnel syndrome patients

Zuniga

Ghavanini

Israelian

et al. 2020

Journal Orthopaedic Research

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Carpal tunnel syndrome (CTS) is a peripheral neuropathy resulting from chronic median nerve compression. Chronic compression leads to neurological changes that are quantified through nerve conduction studies (NCS). Although NCS represents the gold standard in CTS assessment, they provide limited prognostic value. Several studies have identified ultrasound as a tool in diagnosing and potentially predicting the progression of CTS in patients. The purpose of this study was to evaluate the predictive value of ultrasound examination in CTS patients. Twenty patients recruited at their first visit with the neurologist completed two NCS and ultrasound examinations approximately 6 months apart. Ultrasound examination consisted of B‐mode, pulse‐wave Doppler and colour Doppler ultrasound videos and images to quantify median nerve cross‐sectional area, intraneural blood flow velocity in three wrist postures (15° flexion, neutral, and 30° extension), and displacement of the flexor digitorum superficialis (FDS) tendon and the adjacent subsynovial connective tissue (SSCT) of the middle finger during repetitive finger flexion‐extension cycles. A questionnaire was administered to assess the work‐relatedness of CTS. Linear regression analyses revealed that intraneural blood flow velocity (R2 = 0.36, p = .03), assessed in wrist flexion, and relative FDS‐SSCT displacement (R2 = 0.27, p = .04) and shear strain index (R2 = 0.28, p = .04) were significant predictors of nerve sensory and motor changes at 6 months. Results suggest the possibility of using a battery of ultrasound measures as viable markers to predict median nerve functional changes within 6 months.

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“…4 The estimated prevalence is 9.2% in females and 6% in males with approximately 500 000 decompressions per year. 14 The prevalence of CTS is estimated at 3.8% of the general population, 10 leading to substantial morbidity and work absenteeism. 2 The ideal confirmatory diagnostic test needs to have high diagnostic accuracy and the ability to assess severity of disease.…”

Section: Introductionmentioning

confidence: 99%