Correlación manométrica, histológica e histoquímica en el estudio de megacolon en el niño

Abstract

Megacolon in children: Manometry, histology and histochemistry.Ninety-six anorectftl manometric studies were performed in children with megacolon Sixteen patients had pressure records compatibles with Hirschsprung's disease: in twelve the rectal suction biopsy and study of acetylcholinesterase activity confirmed the diagnosis of aganglionosis.In two pacients with non conclusive manometry, acetylcholinesterase activity was highly positive: in one the diagnosis ofcolonicneuronal dysplasia through the study of succinic dehydrogenase was confirmed.