Correction: Prevalence of polypharmacy and the association with non-communicable diseases in Qatari elderly patients attending primary healthcare centers: A cross-sectional study

Al-Dahshan, Ayman; Al-Kubiasi, Noora; Al-Zaidan, Manal; Saeed, Wael; Kehyayan, Vahe; Bougmiza, Iheb

doi:10.1371/journal.pone.0238343

Cited by 5 publications

(4 citation statements)

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“…The previously published studies investigating MRCI had focused on elderly patients with multiple co-morbidities, polypharmacy, and subsequently higher medication regimen complexity [ 34 , 35 ]. This was demonstrated in our population of this study and in similar studies done before, indicating that polypharmacy is prevalent in elderly population in Qatar [ 30 , 31 ]. While hospital readmission was one of the most common health care outcomes studied in association with the MRCI score, data showed mixed results.…”

Section: Discussionsupporting

confidence: 89%

Implications of the medication regimen complexity index score on hospital readmissions in elderly patients with heart failure: a retrospective cohort study

et al. 2023

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Background The likelihood of elderly patients with heart failure (HF) being readmitted to the hospital is higher if they have a higher medication regimen complexity index (MRCI) compared to those with a lower MRCI. The objective of this study was to investigate whether there is a correlation between the MRCI score and the frequency of hospital readmissions (30-day, 90-day, and 1-year) among elderly patients with HF. Methods In this single-center retrospective cohort study, MRCI scores were calculated using a well-established tool. Patients were categorized into high (≥ 15) or low (< 15) MRCI score groups. The primary outcome examined the association between MRCI scores and 30-day hospital readmission rates. Secondary outcomes included the relationships between MRCI scores and 90-day readmission, one-year readmission, and mortality rates. Multivariate logistic regression was employed to assess the 30- and 90-day readmission rates, while Kaplan-Meier analysis was utilized to plot mortality. Results A total of 150 patients were included. The mean MRCI score for all patients was 33.43. 90% of patients had a high score. There was no link between a high MCRI score and a high 30-day readmission rate (OR 1.02; 95% CI 0.99–1.05; p < 0.13). A high MCRI score was associated with an initial significant increase in the 90-day readmission rate (odd ratio, 1.03; 95% CI, 1.00-1.07; p < 0.022), but not after adjusting for independent factors (odd ratio, 0.99; 95% CI, 0.95–1.03; p < 0.487). There was no significant difference between high and low MRCI scores in their one-year readmission rate. Conclusion The study’s results indicate that there is no correlation between a higher MRCI score and the rates of hospital readmission or mortality among elderly patients with HF. Therefore, it can be concluded that the medication regimen complexity index does not appear to be a significant predictor of hospital readmission or mortality in this population.

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Section: Discussionsupporting

confidence: 89%

Implications of the medication regimen complexity index score on hospital readmissions in elderly patients with heart failure: a retrospective cohort study

et al. 2023

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“…The previously published studies investigating MRCI had focused on elderly patients with multiple co-morbidities, polypharmacy, and subsequently higher medication regimen complexity [34,35]. This was demonstrated in our population of this study and in similar studies done before, indicating that polypharmacy is prevalent in elderly population in Qatar [30,31]. While hospital readmission was one of the most common health care outcomes studied in association with the MRCI score, data showed mixed results.…”

Section: Discussionsupporting

confidence: 66%

Implications of the Medication Regimen Complexity Index Score on Hospital Readmissions in Elderly Patients with Heart Failure: A Retrospective Cohort Study

Abdelbary

Kaddoura

Balushi

et al. 2023

Preprint

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Background The likelihood of elderly patients with heart failure (HF) being readmitted to the hospital is higher if they have a higher medication regimen complexity index (MRCI) compared to those with a lower MRCI. The objective of this study was to investigate whether there is a correlation between the MRCI score and the frequency of hospital readmissions (30-day, 90-day, and 1-year) among elderly patients with HF. Methods The study was a retrospective cohort study conducted at a single center, in which MRCI scores were computed utilizing a published tool for 30 patients with high MRCI scores and 30 patients with low MRCI scores. Results A total of 150 patients were included. The mean MRCI score for all patients was 33.43. Ninety percent of patients had a high score. There was no link between a high MCRI score and a high 30-day readmission rate (OR 1.02; 95% CI 0.99–1.05; p < 0.13). A high MCRI score was associated with an initial significant increase in the 90-day readmission rate (odd ratio, 1.03; 95% CI, 1.00-1.07; p < 0.022), but not after adjusting for independent factors (odd ratio, 0.99; 95% CI, 0.95–1.03; p < 0.487). There was no significant difference between high and low MRCI scores in their one-year readmission rate. Conclusion The study's results indicate that there is no correlation between a higher MRCI score and the rates of hospital readmission or mortality among elderly patients with HF. Therefore, it can be concluded that the medication regimen complexity index does not appear to be a significant predictor of hospital readmission or mortality in this population.

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“…In Qatar, the prevalence of polypharmacy in elderly patients was estimated to be 75%-88% (19,40), and potentially inappropriate medication use was 38%-75% (15,44), concluding a higher number of drugrelated problems in our elderly population (45). The increasing and cumulative evidence from Qatar and the Middle East about polypharmacy and its negative consequences among our elderly population is indicating and necessitating deprescribing.…”

Section: Introductionmentioning

confidence: 98%

“…Despite the evidence that deprescribing is bene cial and the availability of many guidelines encouraging clinicians to deprescribe; it was insu ciently evaluated in the Middle East and the Gulf countries. Polypharmacy and potentially inappropriate medication use is highly prevalent in Qatar and other Gulf and Middle East countries as well (15,16,17,(40)(41)(42)(43).…”

Section: Introductionmentioning

confidence: 99%

Validation and Assessment of Patients' and Their Caregivers' Attitude Toward Medications Deprescribing in Qatar: A Cross-sectional study of Home Health Care Services in Qatar

Mohamed,

Yakti,

Mubarak

et al. 2024

Preprint

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Introduction: Polypharmacy remains a pressing concern among the elderly population, often leading to adverse drug reactions (ADRs), emergency department (ED) visits, and hospital admissions. Studies have underscored polypharmacy as a robust predictor of potentially inappropriate medication use and associated poor clinical outcomes in individuals aged 65 and older. Despite the decline in medical treatment effectiveness with aging, patients and caregivers often express reluctance to discontinue regular medications, necessitating a deeper understanding of their perceptions and beliefs regarding deprescribing. Methods: This study aimed to assess the attitudes and perceptions of patients and their caregivers toward deprescribing of medications in Qatar. The first phase involved translating and validating the caregivers' version of the revised Patients’ Attitudes Toward Deprescribing (rPATD) tool. Subsequently, a prospective cross-sectional study was conducted, utilizing validated self-administered questionnaires in both English and Arabic. Results: a significant proportion of both patients and caregivers perceived their medication burden as inconvenient and burdensome. While satisfaction with current medications was generally high, a notable willingness to discontinue medications under physician recommendation was observed. Moreover, participants expressed a strong desire to be involved in deprescribing decision-making processes, highlighting a culture of person-centered care. Despite this, concerns regarding adverse events, medication efficacy, and the necessity of medications persisted among respondents. Conclusion:this study provides insights into the attitudes and perceptions surrounding deprescribing among elderly patients and their caregivers in Qatar, emphasizing the importance of tailored deprescribing strategies and shared decision-making in clinical practice.

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Correction: Prevalence of polypharmacy and the association with non-communicable diseases in Qatari elderly patients attending primary healthcare centers: A cross-sectional study

Abstract: The following information is missing from the Funding statement: Open Access funding is provided by the Qatar National Library.

Cited by 5 publications

References 1 publication

Implications of the medication regimen complexity index score on hospital readmissions in elderly patients with heart failure: a retrospective cohort study

Implications of the medication regimen complexity index score on hospital readmissions in elderly patients with heart failure: a retrospective cohort study

Implications of the Medication Regimen Complexity Index Score on Hospital Readmissions in Elderly Patients with Heart Failure: A Retrospective Cohort Study

Validation and Assessment of Patients' and Their Caregivers' Attitude Toward Medications Deprescribing in Qatar: A Cross-sectional study of Home Health Care Services in Qatar

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