“…Finally, in the last decades a strong interest arose on the exploitation of biopolymers in the design of (bio)sensors for pharmaceutical and biomedical sectors, mainly driven by low-cost applications. In particular, paper has shown several advantages (e.g., compatibility with biological samples, environmental sustainability, ease assembling, storage, and transport, and adaptability as support for printing technologies) that make it an ideal substrate in highly engineered diagnostic devices (Yetisen et al, 2013;Meredith et al, 2016;Lee et al, 2018;Noviana et al, 2019). This last requirement represents an important and urgent topic declared by the World Health Organization, which is particularly interested in biomedical research toward the design of sensitive, cost-effective equipmentfree diagnostic tools devoted to both developed and developing countries (Urdea et al, 2006).…”