Corpora amylacea in mesial temporal lobe epilepsy: Clinico-pathological correlations

Cuerpos amiláceos en la neocorteza de pacientes con epilepsia del lóbulo temporal y displasia cortical focal

“…En estudios previos 10,11,17 o series de pacientes 8,9,15,18,19,[21][22][23][24][25][26] han descrito la acumulación abundante de CoA en la neocorteza y en el hipocampo de pacientes con ELTFR y EH. En los hipocampos resecados, los CoA han sido observados en las siguientes áreas: CA1, CA3 y CA4, folium terminal y fascia dentada, y en menor grado en la corteza parahipocampal 8,15,25 .…”

“…El grupo de pacientes con ELTFR-EHCoA+ presentaron una mayor edad al momento de la cirugía, así como una duración prolongada de la epilepsia comparado con el grupo sin CoA. A pesar de que la evolución clínica fue comparable en ambos grupos, se observó un número mayor de pacientes libres de FAE en el grupo sin CoA 24 .…”

A Prospective Study on the Cost-Effective Utilization of Long-Term Inpatient Video-EEG Monitoring in a Developing Country

“…Majority of the studies on VEM have concentrated on the sensitivity and specificity of seizure semiological signs and EEG findings in the diagnosis of epilepsies and in the presurgical localization of seizure origin (Blume et al, 1998;Ebersole and Pacia, 1996;Hirfanoglu et al, 2007;Williamson et al, 1998). This study from a comprehensive epilepsy care program, which has undertaken the maximum number of epilepsy surgeries in India during the last one decade (Radhakrishnan et al, 2007;Rao and Radhakrishnan, 2000;Rathore et al, 2007), to our knowledge, is the first of its kind that has assessed diagnostic value and cost effectiveness of VEM from a developing country. We accept patients for inpatient long-term VEM only after they have had a thorough assessment by an epileptologist concerning the indication for VEM.…”

“…Patients with difficult to control epilepsies are referred to this center from all regions of South India and elsewhere from India. This center has undertaken over 900 epilepsy surgeries during the past 12 years (Radhakrishnan et al, 2007;Rao and Radhakrishnan, 2000;Rathore et al, 2007). The Epilepsy Monitoring Unit has three VEM beds.…”

Sexual desire and satisfaction after resective surgery in patients with mesial temporal lobe epilepsy with hippocampal sclerosis

“…The standard ATL carried out under general anesthesia by the same neurosurgeon consisted of excision of the neocortical structures, followed by microsurgical resection of the amygdala, and en bloc resection of the hippocampus and parahippocampal gyrus. The histopathological findings were reviewed, and the diagnosis of MTLE-HS was confirmed in each of the selected patients by the loss of neuronal cell population of 30% or more in the CA1 sector of the hippocampal formation with or without neuronal loss and gliosis involving other mesial temporal structures [16]. After ATL, we routinely follow-up the patients at 3 months, at one year, and at yearly intervals thereafter.…”