Coronavirus disease 2019 in pregnant and non-pregnant women: a retrospective study

Abstract

Coronavirus disease 2019 arises from infection with the new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). [1] The susceptible population can be of any age and gender; thus, the disease threatens the health and life of everyone, including pregnant women. Pregnancy can influence the physiological function of various organs, and thus may affect the prognosis of many infectious diseases. For example, higher mortality rates and more complications were reported in pregnant patients infected with SARS-CoV than those in non-pregnant patients. [2] Clinical manifestations and treatment monitoring of pregnant women with COVID-19 have been reported in previous studies, [3] which mainly focus on maternal and neonatal outcomes by analyzing small sample size data, but studies regarding the influence of pregnancy on the progression and prognosis of COVID-19 remain relatively rare. In this study, we retrospectively analyzed clinical data from women of childbearing age with COVID-19 at Tongji Hospital to explore the impact of pregnancy on the progression of COVID-19 and provide a theoretical basis for the effective diagnosis and treatment of pregnant women with COVID-19.In this retrospective, single-center cohort study, we recruited childbearing-aged women with COVID-19 pneumonia admitted to Tongji Hospital

Clinical Outcomes of COVID-19 Infection in Pregnant and Nonpregnant Women: Results from The Philippine CORONA Study

“…Based on a local study, about 35% of COVID-19-infected pregnant women were symptomatic [ 2 ]. Similar to our result, they commonly present with fever and cough [ 2 , 3 , 8 , 19 ]. Compared with nonpregnant women, pregnant women more frequently present with colds and anosmia, while the former mostly present with cough, dyspnea, chills, fatigue, and headache [ 7 ].…”

“…Earlier reports in the Philippines indicated that several pregnant COVID-19 patients were asymptomatic, ranging from 22 to 42% of individuals [ 2 , 3 , 4 ]. Previous studies have also suggested that pregnant women with COVID-19 have a favorable clinical course compared with the nonpregnant population [ 2 , 5 , 6 , 7 , 8 , 9 , 10 ]; however, pre-existing diseases may increase the probability of hospitalization [ 9 ]. An increased risk of acquiring severe disease was found in pregnant women with comorbidities, including those who presented with fever, cough, headache, dyspnea, and diarrhea [ 3 ].…”

Maternal COVID-19 and neonatal hearing loss: a multicentric survey

“…Most studies report no ill-effects on either mother or newborn and no evidence of transplacental or vertical transmission [23]. In a few studies, premature labor, low birth weight or neonatal asphyxia were reported [24][25][26][27][28][29][30]. However, with the evolution of the pandemic, various neurotropic effects of the virus have been reported [1-3, 6, 31, 32].…”

Risk Factors and Clinical Outcomes Associated With Acute Respiratory Distress Syndrome in Pregnant and Non-pregnant Women Diagnosed With COVID-19: A Comparative Analysis

“…These findings are consistent with the observation made by Mohr-Sasson et al [ 14 ], wherein they reported no significant difference in laboratory indices among pregnant and non-pregnant cohorts. Zha et al [ 15 ] also reported mild differences in the laboratory characteristics of pregnant women compared to non-pregnant women; however, they suggested that these differences were due to physiological and immunological changes during pregnancy rather than a disease per se.…”