Coronavirus disease 2019 and cardiovascular system: A narrative review

Kwenandar, Felix; Japar, Karunia Valeriani; Damay, Vika; Hariyanto, Timotius Ivan; Tanaka, Michael; Lugito, Nata Pratama Hardjo; Kurniawan, Andree

doi:10.1016/j.ijcha.2020.100557

Cited by 111 publications

(121 citation statements)

References 26 publications

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“…( Hariyanto and Kurniawan, 2020 ) Several comorbidities have been demonstrated to be associated with severe COVID-19 outcomes such as hypertension, diabetes, dyslipidemia, anemia, cardiovascular disease, thyroid disease, and pulmonary disease. ( Huang et al, 2020 , Kwenandar et al, 2020 , Hariyanto and Kurniawan, 2020 , Hariyanto and Kurniawan, 2020 ) During normal times, individuals with dementia are the most vulnerable persons as they depend on other people for their day to day survival. In a previous study, it has been shown that dementia increases the risk of morbidity and mortality among hospitalized patients, including the severity of the respiratory disease.…”

Section: Introductionmentioning

confidence: 99%

Dementia and outcomes from coronavirus disease 2019 (COVID-19) pneumonia: A systematic review and meta-analysis

Hariyanto

Putri

Arisa

et al. 2021

Archives of Gerontology and Geriatrics

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105

107

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Section: Introductionmentioning

confidence: 99%

Dementia and outcomes from coronavirus disease 2019 (COVID-19) pneumonia: A systematic review and meta-analysis

Hariyanto

Putri

Arisa

et al. 2021

Archives of Gerontology and Geriatrics

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105

107

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“…The number of positive and death cases from COVID-19 is still increasing. The manifestation of COVID-19 range from mild respiratory symptoms such as fever and cough to severe and potentially lethal symptoms such as sepsis, arrhythmia, heart failure, and loss of consciousness [ 1 ]. Several comorbid conditions, including dyslipidemia, have been identified to be associated with the development of severe outcomes from COVID-19 [ 2 ].…”

Section: Introductionmentioning

confidence: 99%

Statin therapy did not improve the in-hospital outcome of coronavirus disease 2019 (COVID-19) infection

Hariyanto

Kurniawan

2020

Diabetes & Metabolic Syndrome: Clinical Research & Revi

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Background and aims The coronavirus disease 2019 (COVID-19) number of death cases is still increasing. One of the comorbidities associated with severe outcome and mortality of COVID-19 is dyslipidemia. Statin is one of the drugs which is most commonly used for the treatment of dyslipidemic patients. This study aims to analyze the association between statin use and in-hospital outcomes of COVID-19 infection. Methods We systematically searched the Google Scholar database using specific keywords related to our aims until August 1st, 2020. All articles published on COVID-19 and statin were retrieved. Statistical analysis was done using Review Manager 5.4 software. Results A total of 9 studies with a total of 3449 patients were included in our analysis. Our meta-analysis showed that statin use did not improve severity outcome [OR 1.64 (95% CI 0.51–5.23), p = 0.41, I 2 = 93%, random-effect modelling] nor mortality rate from COVID-19 infection [OR 0.78 (95% CI 0.50–1.21), p = 0.26, I 2 = 0%, fixed-effect modelling]. Conclusion Statin use did not improve in-hospital outcomes of COVID-19 infections. Patients with dyslipidemia should continue taking statin drugs despite COVID-19 infection status, given its beneficial effects on cardiovascular outcomes.

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“…1,2 Patients with COVID-19 can report a wide variety of clinical manifestations, from mild symptoms, such as fever and cough, to severe symptoms, such as shortness of breath, arrhythmia, and loss of consciousness. 3,4 Part of the patients are also reporting the presence of symptoms of olfactory dysfunction, such as anosmia and hyposmia. These symptoms become more prominent in patients with COVID-19 infection.…”

Section: Introductionmentioning

confidence: 99%

Anosmia/Hyposmia is a Good Predictor of Coronavirus Disease 2019 (COVID-19) Infection: A Meta-Analysis

Hariyanto

Rizki

Kurniawan

2020

Int Arch Otorhinolaryngol

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Introduction The number of positive cases and deaths from the coronavirus disease 2019 (COVID-19) is still increasing. The early detection of the disease is very important. Olfactory dysfunction has been reported as the main symptom in part of the patients. Objective To analyze the potential usefulness of anosmia or hyposmia in the detection of the COVID-19 infection. Data Synthesis We systematically searched the PubMed Central database using specific keywords related to our aims until July 31st, 2020. All articles published on COVID-19 and anosmia or hyposmia were retrieved. A statistical analysis was performed using the Review Manager (RevMan, Cochrane, London, UK) software, version 5.4. A total of 10 studies involving 21,638 patients were included in the present analysis. The meta-analysis showed that anosmia or hyposmia is significantly associated with positive COVID-19 infections (risk ratio [RR]: 4.56; 95% confidence interval [95%CI]: 3.32–6.24; p < 0.00001; I2 = 78%, random-effects modeling). Conclusion The presence of anosmia or hyposmia is a good predictor of positive COVID-19 infections. Patients with onset of anosmia or hyposmia should take the test or undergo screening for the possibility of COVID-19 infection.

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Coronavirus disease 2019 and cardiovascular system: A narrative review

Cited by 111 publications

References 26 publications

Dementia and outcomes from coronavirus disease 2019 (COVID-19) pneumonia: A systematic review and meta-analysis

Dementia and outcomes from coronavirus disease 2019 (COVID-19) pneumonia: A systematic review and meta-analysis

Statin therapy did not improve the in-hospital outcome of coronavirus disease 2019 (COVID-19) infection

Anosmia/Hyposmia is a Good Predictor of Coronavirus Disease 2019 (COVID-19) Infection: A Meta-Analysis

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