Coronary Surgery in Patients With Preexisting Chronic Atrial Fibrillation: Early and Midterm Clinical Outcome

Comparing the outcome of on-pump versus off-pump coronary artery bypass grafting in patients with preoperative atrial fibrillation

“…Several studies have demonstrated that PAF is an independent risk factor for early and late mortality after cardiac operations [2,5,9,[14][15][16]. The reasons associated with a worse outcome and the reduction in survival rate after cardiac surgery in these patients remain unclear.…”

“…The reasons associated with a worse outcome and the reduction in survival rate after cardiac surgery in these patients remain unclear. A high incidence of hemorrhagic/thromboembolic events may be one of the contributing factors in reducing the survival rate [14], but PAF has not been identified as the predictor of early postoperative cerebrovascular events [10]. Furthermore, tachyarrhythmia-associated cardiomyopathy may be another factor contributing to decreased survival rate in these patients [17,18].…”

The impact of preoperative atrial fibrillation on early and late mortality after coronary artery bypass grafting

“…Rogers et al [12] demonstrated a survival deficit up to 5 years after CABG in patients with preoperative AF compared with SR, with an adjusted effect size of 1.49 (95% CI: 1.06-2.08). Only patients who had permanent or multiple recurrent episodes during the last 6 months were included, which could have had an effect on the outcome [12].…”

“…Rogers et al [12] demonstrated a survival deficit up to 5 years after CABG in patients with preoperative AF compared with SR, with an adjusted effect size of 1.49 (95% CI: 1.06-2.08). Only patients who had permanent or multiple recurrent episodes during the last 6 months were included, which could have had an effect on the outcome [12]. In a recent report of Kalavrouziotis et al [20], increased late mortality and recurrent cardiovascular events after cardiac surgery was associated with preoperative AF.…”

“…Some studies have identified AF as an independent risk factor for mortality [4][5][6]. The effect of pre-existing AF on early and late mortality after coronary artery bypass grafting (CABG) has not been studied extensively [8][9][10][11][12].…”