2022
DOI: 10.1016/j.jacc.2021.10.035
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Coronary Atherosclerotic Plaque Regression

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Cited by 53 publications
(39 citation statements)
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References 129 publications
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“…Atherosclerosis is a common type of cardiovascular disease in the elderly population. Carotid atherosclerotic plaque is a natural part of the atherosclerosis process and tends to occur at the bifurcation of the carotid artery and at the beginning of the segment where blood flow is slower [ 13 , 14 ]. The higher IPN classification suggests a greater risk of plaque instability, plaque dislodgement, or even intraplaque hemorrhage [ 15 ].…”
Section: Discussionmentioning
confidence: 99%
“…Atherosclerosis is a common type of cardiovascular disease in the elderly population. Carotid atherosclerotic plaque is a natural part of the atherosclerosis process and tends to occur at the bifurcation of the carotid artery and at the beginning of the segment where blood flow is slower [ 13 , 14 ]. The higher IPN classification suggests a greater risk of plaque instability, plaque dislodgement, or even intraplaque hemorrhage [ 15 ].…”
Section: Discussionmentioning
confidence: 99%
“…Thus, the atherosclerotic plaque growth is now a focus of great interest because preventing the progression of the plaque seems a feasible and crucial step to avoid its complications. Several imaging modalities have been proposed for monitoring the progression of the disease, especially the coronary computed tomographic angiography due to quality of imaging and because it is a non-invasive imaging modality ( Dawson et al, 2022 ). Intensive lipid-lowering and anti-inflammatory strategies have been proposed to prevent plaque progression.…”
Section: Inflammation and Vulnerable Plaquementioning
confidence: 99%
“…The incidence of CAD is 176.3/100,000 inhabitants, whereas the prevalence of this disease is 2,270/100,000 inhabitants ( 2 ). CAD is the most important cause of death in patients with CVD ( 5 ), accounting for 38% of overall deaths ( 2 ). In addition, the DALY associated with CAD approaches 54% of the total DALYS caused by CVD ( 2 ).…”
Section: Cardiovascular Diseases Managementmentioning
confidence: 99%
“…The latter forms a fibrous cap and, ultimately, an established atherosclerotic plaque ensues. The narrowing luminal provoked by plaque or plaque rupture-associated thrombus superposition are the main mechanisms behind the clinical manifestations of CAD ( 5 ). However, thrombus and coronary spasm even in the angiographically proven normal epicardial coronary arteries are well other recognized causes of CAD.…”
Section: Cardiovascular Diseases Managementmentioning
confidence: 99%