Coronary Artery Obstruction After the Arterial Switch Operation for Transposition of the Great Arteries in Newborns

Abstract

Selective coronary angiography is the most accurate means to assess coronary artery obstruction after the arterial switch operation. Precise diagnosis of coronary artery lesions after this operation will help to elucidate the pathogenesis, develop adequate therapeutic strategies and might indicate how to prevent coronary complications after operation.

Noninvasive Assessment of Autonomic Cardiovascular Function in Patients after Arterial Switch Operation for Transposition of the Great Arteries

“…However, late death generally occurs during childhood and is exceedingly rare in adulthood [15]- [20]. Nevertheless, we cannot assume that the problem disappears when childhood is over.…”

“…Nevertheless, we cannot assume that the problem disappears when childhood is over. The potential for silent myocardial ischemia in this setting, emphasis on the need for efficient screening for coronary complications, and routine coronary angiography has been suggested during adolescence and/or adulthood to be a part of the long-term follow-up [19] [20]. However, efficient screening is important, especially since patients with denervated hearts may not experience any symptoms of myocardial ischemia.…”

“…In the long-term, the main causes of death in patients with TGA who have had ASO seem to be myocardial ischemia and sudden death [15]- [20]. Efficient screening is thus important, especially since patients with denervated hearts may not experience any symptoms of myocardial ischemia.…”

Transposition of the great arteries. Evaluation of the results and current management

“…Mid-term follow-up is greatly influenced by coronary events after the Jatene procedure, as demonstrated in several studies (table III), where coronaryangiographies show them to occur in 3 to 11% of the cases during a 5-year follow-up after the surgery, with a mortality rate ranging from 0 to 10% [2][3][4][5][6] .…”

“…Complications from these pre-existing factors or resulting from the technique itself are mainly represented by ventricular failure, coronary events, right ventricular outflow tract obstruction, and regurgitation of the new aortic valve [2][3][4][5][6][7] .…”