Coronary artery disease associated with factor V Leiden mutation: a case report

Inherited thrombophilia transpires with severe coronary arterial thrombosis in wide range of age backgrounds: A report of 3 cases

“…Inherited thrombophilia, a collection of hereditary diseases that predispose to thrombosis and are characterized by heritable deficits of the endogenous anticoagulants proteins and antithrombin, is linked to an increased risk of thromboembolism. It can potentially be the cause of coronary artery disease (CAD) and myocardial infarction (MI), especially in young adults [ 1 ]. One of the most common variants of the thrombopohilia is because of factor V Leiden gene mutation, which results in resistance to protein C inactivation.…”

“…One of the most common variants of the thrombopohilia is because of factor V Leiden gene mutation, which results in resistance to protein C inactivation. Other causes of inherited thrombophilia include protein C, protein S, and antithrombin deficiency [ 1 ].…”