Coronary Angiographic Features within 48 Hours from Onset of Non-Q Wave Myocardial Infarction with R Wave Regression and No ST Segment Depression

Abstract

The clinical features of acute non-Q wave myocardial infarction (NQMI) with R wave regression and no ST segment depression are distinct from those of acute Q wave myocardial infarction (QMI). NQMI patients showed ST segment elevation at admission, and significantly earlier regression of the ST segment elevation and appearance of coronary T waves were observed compared to QMI patients. In addition to the significantly lower level of mean peak serum creatine kinase activity and the significantly lower incidence of pump failure during the acute phase, the incidences of in-hospital mortality and multivessel disease were significantly lower in the NQMI patients. With respect to acute-phase coronary angiographic features within 48 h after the onset, the rate of spontaneous opening of infarct-related vessels was significantly higher in the NQMI patients. Thirteen of the 19 NQMI patients responded to urokinase infusion. These facts suggest that transient, intermittent or incomplete obstruction may favor this type of NQMI over QMI, and that thrombus might be an important factor in the pathogenesis of this type of NQMI.

Correlation between P Wave Dispersion, QRS Duration and QT Dispersion in Hospital Events in Cases of Acute Coronary Syndrome

“…For many patients with non Q-wave infarction, the underlying angiographic finding is a recanalized vessel [89]. The prognosis of non Q-wave infarction is markedly predicted by the admission ECG [90].…”

La apoptosis en el Infarto Agudo de Miocardio. Asociación de los polimorfismos Arg72Pro del gen P53 y T309G del gen MDM2 con el tamaño del infarto, la función ventricular izquierda post-infarto y el desarrollo de insuficiencia cardiaca

“…Aunque los resultados de este estudio son concordantes con nuestros hallazgos, creemos que existen varias limitaciones en su diseño. En primer lugar, incluyeron pacientes con perfil clínico diferente (SCASEST y SCACEST)[278][279][280][281][282] por lo que la estimación del tamaño del IAM de forma conjunta puede no ser del todo precisa. Además, 32 pacientes tenían AI (marcadores cardiacos normales por definición).…”