Corneal perforation associated with isolated ocular lichen planus: a case report

Gomez-Elizondo, Daniela; López-Martínez, Mariana; Ruiz-Lozano, Raúl E.; Valdez-García, Jorge E.; Hernández-Camarena, Julio C.

doi:10.1177/1120672120932089

Cited by 5 publications

(17 citation statements)

References 10 publications

(30 reference statements)

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“…Corneal scarring may occur after a myriad of causes, including herpetic keratitis, corneal trauma, previous corneal infections, chemical and thermal burns, NK, corneal hydrops (Figures 3A, B), cicatrizing keratoconjunctivitis, and autoimmune corneal ulceration [27][28][29]. Scarring results in a reduced quality of vision because of leukoma formation, high-order aberrations, and irregular astigmatism.…”

Section: Abbreviationsmentioning

confidence: 99%

Update on indications, complications, and outcomes of scleral contact lenses

Ruiz-Lozano¹,

Gomez-Elizondo²,

Colorado-Zavala³

et al. 2022

Med Hypothesis Discov Innov Ophthalmol

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Background: The role of scleral contact lenses (SCLs) has increasingly expanded since the first lens was fitted more than a century ago. While it was initially prescribed for the management of severely compromised corneas, the indications for modern SCL use have expanded to include less severe diseases. In this review, we aimed to provide an up-to-date overview of the current indications, complications, and outcomes for the various types of SCLs. Methods: In this narrative review, we thoroughly searched the PubMed/MEDLINE database for literature published from January 1980 to November 2021. Only relevant up-to-date English references were included. Furthermore, the figures in this manuscript were derived from our unit’s patient documentation. Results: Currently, SCLs can successfully be used to manage ocular surface diseases, visually rehabilitate irregular corneas, and correct irregular refractive errors. Although newer materials have yielded the same visual outcomes with fewer complications, these consequences still occur in approximately one-third of contact lens wearers, including difficulties in insertion and/or removal, discomfort or pain, and developing either halos, blurriness, or haze. Even though most of these complications are minor and can be easily treated, a good practice is essential to avoid sight-threatening complications such as microbial keratitis. Conclusions: SCLs are indispensable in ophthalmic clinics. The development of better-quality SCLs has increased the number of indications and improved the achievable visual rehabilitation. The future of developing improvements in SCL design, materials, and fit, and the expansion of their indication range is promising.

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Section: Abbreviationsmentioning

confidence: 99%

Update on indications, complications, and outcomes of scleral contact lenses

Ruiz-Lozano¹,

Gomez-Elizondo²,

Colorado-Zavala³

et al. 2022

Med Hypothesis Discov Innov Ophthalmol

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“…Classic findings include a shaggy staining of antifibrinogen with weak anti-C3 staining in the basement membrane zone. 4,13…”

Section: Histopathologic Findingsmentioning

confidence: 99%

“…10 Recently, a case of corneal perforation due to LP was reported. 13 Table 3 shows the reported cases of isolated ocular LP.…”

Section: Ocular Manifestationsmentioning

confidence: 99%

“…13 The latter, results in corneal scarring, observed as an opacified "white eye," neovascularization, stromal melting, ulceration, and an increased risk of perforation. 10,13…”

Section: Natural History Of Lp Lpp and Lpl In The Eyementioning

confidence: 99%

“…The relevance of differentiating between ocular LP and ocular mucous membrane pemphigoid (OMMP), clinically indistinguishable diseases, relies on required treatment. 13,15 While ocular LP responds to topical steroids at initial stages, active OMMP always requires systemic immunosuppression, preferably with prednisone and CYC. 2,50 Of note, biological agents (i.e., rituximab) may be considered instead of CYC for ovarian protection.…”

Section: Treatmentmentioning

confidence: 99%

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Ocular involvement and complications of lichen planus, lichen planus pigmentosus, and lichen planopilaris: A comprehensive review

Ruiz-Lozano

Hernández-Camarena

Valdez-García

et al. 2021

Dermatologic Therapy

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Ocular involvement of lichenoid dermatoses, such as lichen planus (LP), lichen planus pigmentosus (LPP), and lichen planopilaris (LPL), although uncommon, is associated with skin manifestations. Isolated ocular involvement is very rare.When lesions are confined to the skin, the dermatologist inquires and evaluates for oral and genital symptoms and lesions, respectively; hence, eye manifestations are commonly neglected by the non-ophthalmologist. Ocular involvement in LP, LPP, and LPL may result in significant morbidity. An ophthalmic interrogatory and a gross ophthalmic evaluation performed by the dermatologist may unravel ocular signs and symptoms that require evaluation by an eye specialist. Ocular surface inflammation and scarring, when untreated, results in serious complications such as corneal perforation and permanent vision loss. This review aims to present an up-to-date overview for the dermatologist of the ocular involvement

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Peripheral Ulcerative Keratitis Associated With Lichen Planus

Neo,

Farwana,

Ahmoye

et al. 2023

Cornea

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The aim of this study was to report a case of peripheral ulcerative keratitis (PUK) associated with lichen planus.Methods: A 42-year-old woman with histological confirmation of lichen planus from an oral buccal mucosa biopsy presented with bilateral peripheral stromal thinning and an epithelial defect, in keeping with PUK.Results: All screening for known causes of PUK were negative, and lichen planus was presumed as the etiological factor. Oral prednisolone 1 mg/kg was initiated, alongside topical steroids and topical ciclosporin. The PUK resolved after 3 months, and a slowtapering regimen of oral prednisolone was needed to prevent a relapse of ocular surface inflammation. Topical steroids were also tapered and discontinued after 5 months, and the ocular surface remained stable with topical ciclosporin with no relapse after 1 year.Conclusions: Ocular manifestations of lichen planus are rare and mostly involve the conjunctiva; however, PUK might also develop, presumably due to its similar mechanisms with other T-cell autoimmune diseases. Systemic immunosuppression is required initially but further control of the ocular surface can be achieved successfully with topical ciclosporin.

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Corneal perforation associated with isolated ocular lichen planus: a case report

Cited by 5 publications

References 10 publications

Update on indications, complications, and outcomes of scleral contact lenses

Update on indications, complications, and outcomes of scleral contact lenses

Ocular involvement and complications of lichen planus, lichen planus pigmentosus, and lichen planopilaris: A comprehensive review

Peripheral Ulcerative Keratitis Associated With Lichen Planus

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