Corneal Inflammation Following Corneal Photoablative Refractive Surgery With Excimer Laser

Alió, Jorge L.; Javaloy, Jaime

doi:10.1016/j.survophthal.2012.04.005

Cited by 53 publications

(30 citation statements)

References 109 publications

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“…According to our longitudinal comparison, similar efficacy and safety outcomes were found over the year except for the first postoperative month. The comparatively poorer visual outcome during the early postoperative period following PRK could represent a differential healing response between the two techniques 21. It also coincides with the period of transient corneal haze observed in post-PRK eyes.…”

Section: Discussionmentioning

confidence: 59%

Longitudinal comparison of femtosecond-assisted sub-Bowman keratomileusis versus photorefractive keratectomy for high myopia

Chan

Mak

et al. 2016

Br J Ophthalmol

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Section: Discussionmentioning

confidence: 59%

Longitudinal comparison of femtosecond-assisted sub-Bowman keratomileusis versus photorefractive keratectomy for high myopia

Chan

Mak

et al. 2016

Br J Ophthalmol

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“…The increased evaporation or reduced tear production due to rise of the tear osmolarity and inflammatory origin of ocular surface. The many mediators released by damage to the nerve endings and cells from the corneal photoablation after cause the degranulation of mast cells and the recall of leukocytes, monocytes and macrophages with the effect of determining dilation of the blood vessels and hypersensitivity of the tissue [57,58].…”

Section: Dry Eye and Refractive Surgerymentioning

confidence: 99%

Analysis of the Pathogenic Factors and Management of Dry Eye in Ocular Surface Disorders

Nebbioso¹,

Regno²,

Gharbiya³

et al. 2017

Preprint

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The alteration of the delicate balance that regulates the secretion and distribution of the tear film determines the dry eye (DE) syndrome, because the tear film represents the interface between the eye and the environment. Despite having a multifactorial origin, the main risk factors for the emergence of the ocular disease are female gender and advanced age. Peer-reviewed version available at Int. J. Mol. Sci. 2017, 18, 1764 doi:10.3390/ijms18081764 2 Likewise, morphological changes in several glands and in chemical composition of their secretions such as proteins, mucins, lipidics, aqueous tears, and salinity, are highly relevant factors to maintain a condition of good health of the ocular anterior segment. Another key factor of recurrence and onset of the disease is the presence of local and/or systemic infiammation that reflex on the ocular surface. However, it is one of the most commonly encountered disease in clinical practice and many other causes related to daily life and to lengthen the average life will contribute to the beginning. This review will consider how and what disorders of the ocular surface are responsible for a widespread pathology so. In the end, the most appropriate and new therapies will be briefly exposed according to the specific pathology.

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“…In accordance, a recent study in rabbits has demonstrated ReLEx flex to induce less wound healing and inflammation than FS-LASIK, particularly after high myopic corrections [49]. Whether this observation has any clinical consequence remains to be determined; however, wound repair after LASIK and, in particular, PRK has been extensively investigated and is known to influence the postoperative outcome [48,50,51].…”

Section: Experimental Studiesmentioning

confidence: 84%

“…In excimer laser keratorefractive surgery, the energy delivered to the cornea may promote subsequent inflammation and wound repair [48]. In contrast to the excimer laser, femtosecond lasers deliver only minimal amounts of energy to surrounding tissue [49], suggesting that the femtosecond laser may induce less postoperative wound repair.…”

Section: Experimental Studiesmentioning

confidence: 99%

All-Femtosecond Laser Keratorefractive Surgery

Ivarsen

Hjortdal

2013

Curr Ophthalmol Rep

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During the last few years, refractive lenticule extraction (ReLEx) has been introduced as a new approach in the field of keratorefractive surgery. In contrast to previous treatments, ReLEx is an all-femtosecond laser treatment where a refractive lenticule is created within the intact cornea. The lenticule can be removed using a flapbased approach (ReLEx flex), but in its latest evolution (ReLEx smile), the lenticule is extracted through a small peripheral incision, leaving most of the anterior stroma untouched. In theory, this approach should spare most of the corneal nerves and minimize the biomechanical impact of the procedure. Clinical studies have shown the safety and the visual and refractive outcomes after ReLEx to be as good as after FS-LASIK. The current article aims to provide an up-to-date overview of all-femtosecond laser keratorefractive surgery with particular emphasis on the most current of approach, ReLEx smile.

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Corneal Inflammation Following Corneal Photoablative Refractive Surgery With Excimer Laser

Cited by 53 publications

References 109 publications

Longitudinal comparison of femtosecond-assisted sub-Bowman keratomileusis versus photorefractive keratectomy for high myopia

Longitudinal comparison of femtosecond-assisted sub-Bowman keratomileusis versus photorefractive keratectomy for high myopia

Analysis of the Pathogenic Factors and Management of Dry Eye in Ocular Surface Disorders

All-Femtosecond Laser Keratorefractive Surgery

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