Corneal Endothelial Changes in Pseudoexfoliation Syndrome

Miyake, Kensaku; Matsuda, Michihiko; Inaba, Masumi

doi:10.1016/s0002-9394(14)73259-3

Cited by 97 publications

(74 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…It is known that a distinct form of corneal endotheliopathy occurs in patients with PXS. This special endotheliopathy can cause early corneal endothelial decompensation and may have been previously misdiagnosed as an atypical non-guttata Fuchs' endothelial dystrophy (8,18,19) . In addition, in vivo confocal microscopy studies have shown significant morphologic alterations in the corneas of PXS patients (5,(20)(21)(22) .…”

Section: Discussionmentioning

confidence: 99%

Evaluation of anterior segment parameters in patients with pseudoexfoliation syndrome using Scheimpflug imaging

Güneş¹,

Yigit²,

Tök³

et al. 2016

Arquivos Brasileiros De Oftalmologia

View full text Add to dashboard Cite

Approved by the following research ethics committee: Süleyman Demirel University (# 72867572-050). ABSTRACT Purpose:To evaluate anterior segment parameters in patients with pseudoexfoliation syndrome (PXS) using Scheimpflug imaging. Methods: Forty-three PXS patients and 43 healthy control subjects were included in this cross-sectional study. All participants underwent a detailed ophthalmologic examination. Anterior segment parameters were measured using a Scheimpflug system. Results: Considering the PXS and control groups, the mean corneal thicknesses at the apex point (536 ± 31 and 560 ± 31 µm, respectively, p=0.001), at the center of the pupil (534 ± 31 and 558 ± 33 µm, respectively, p=0.001), and at the thinnest point (528 ± 30 and 546 ± 27 µm, respectively, p=0.005) were significantly thinner in PXS patients. Visual acuity was significantly lower (0.52 ± 0.37 versus 0.88 ± 0.23, p<0.001) and axial length was significantly longer (23.9 ± 0.70 mm versus 23.2 ± 0.90 mm, p=0.001) in the PXS eyes than in the control eyes. There were no statistically significant differences in the mean values of keratometry, anterior chamber angle, anterior chamber depth, corneal volume, and anterior chamber volume between the PXS and control eyes. Conclusions: The patients with PXS had thinner corneas, worse visual acuity, and longer axial length compared with those in the healthy controls.

show abstract

Section: Discussionmentioning

confidence: 99%

Evaluation of anterior segment parameters in patients with pseudoexfoliation syndrome using Scheimpflug imaging

Güneş¹,

Yigit²,

Tök³

et al. 2016

Arquivos Brasileiros De Oftalmologia

View full text Add to dashboard Cite

show abstract

“…Reported intraoperative difficulties include increased corneo-endothelial and iris pigment epithelial fragility, increased vascular leakage and inflammation, fibrin deposition, zonular instability often associated with zonular dialysis and vitreous 10ss. [45][46][47][48][49] Post-operative problems may include an increased risk of synechia formation and pupillary block, rapid development of capsular thickening requiring laser capsulotomy, cystoid macular oedema in the presence of capsular trauma resulting in vitreous loss, transient lOP spikes, and progression of glaucoma optic neuropathy. 48 , 49 Consequently, PEX glaucoma coexisting with cataract poses a management dilemma.…”

Section: Trabecular Aspirationmentioning

confidence: 99%

Perspectives in trabecular surgery

Jacobi

Dietlein

2000

Eye

View full text Add to dashboard Cite

show abstract

“…Specular microscopy of the corneal endothelium has revealed a significantly lower than normal cell density in eyes with PXFS and changes in cell size and shape. 16 These finding have also been observed in the unaffected eye of unilateral cases. 16 These changes predispose to early corneal decompensation at only moderate rises of IOP or after cataract surgery.…”

Section: Clinical and Pathologic Features Corneal Changesmentioning

confidence: 53%

Pseudoexfoliation Syndrome and Pseudoexfoliation Glaucoma

M¹,

Gupta²

2017

jemds

View full text Add to dashboard Cite

BACKGROUNDPseudoexfoliation syndrome is a systemic disorder characterised by the deposition of white dandruff-like material within the anterior segment of the eye and other organs such as the heart, lungs and kidneys. The deposition of this material in the trabecular meshwork can result in aqueous flow obstruction, raised intraocular pressure and glaucoma. In fact, pseudoexfoliation glaucoma is the most common form of secondary open-angle glaucoma. In contrast to primary open-angle glaucoma, this disease runs a more aggressive clinical course with high intraocular pressure at onset, faster rates of progression, poor response to medical therapy and increased need for surgical intervention.

show abstract

Corneal Endothelial Changes in Pseudoexfoliation Syndrome

Cited by 97 publications

References 23 publications

Evaluation of anterior segment parameters in patients with pseudoexfoliation syndrome using Scheimpflug imaging

Evaluation of anterior segment parameters in patients with pseudoexfoliation syndrome using Scheimpflug imaging

Perspectives in trabecular surgery

Pseudoexfoliation Syndrome and Pseudoexfoliation Glaucoma

Contact Info

Product

Resources

About