Corneal edema and intraocular pressure after cataract surgery

Moser, Carlos L.; Martı́n-Baranera, Montserrat; Garat, Magela; Miguel, Pedro Vı́ctor de; Rubio, Marc

doi:10.1016/j.jcrs.2004.05.004

Cited by 6 publications

(10 citation statements)

References 25 publications

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“…The loss of corneal endothelium cells after intraocular surgery, especially lens surgery, may cause dysfunction and lead to corneal oedema. 4 The new central port design of the ICL V4c changes the aqueous flow, and may therefore influence corneal endothelium cells.…”

Section: Introductionmentioning

confidence: 99%

Four-year observation of the changes in corneal endothelium cell density and correlated factors after Implantable Collamer Lens V4c implantation

Yang

Zhao

Zhao³

et al. 2020

Br J Ophthalmol

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BackgroundTo evaluate the changes in corneal endothelium cell density (ECD) and the correlated factors after Implantable Collamer Lens (ICL) V4c implantation.MethodsIn this retrospective, consecutive study, 48 eyes of 25 patients with myopia who underwent ICL V4c implantation were enrolled. Patients were followed up for at least 4 years, during which manifest refraction, uncorrected distance visual acuity, corrected distance visual acuity (CDVA), intraocular pressure, ECD, anterior chamber depth, anterior chamber volume (ACV), anterior chamber angle (ACA), vault and distance from the corneal endothelium to the central ICL (C-ICL) were measured. Spearman’s correlation analysis was used to identify variables correlated with changes in ECD, and generalised estimating equation model adjusting within-patient intereye correlations was used to predict changes in ECD.ResultsAll surgeries were performed safely with no complications during follow-up (average 52±2.9 months). Safety and efficacy indices were 1.23±0.22 and 1.04±0.16, respectively. No eyes had decreased CDVA, and 67% gained one or more lines. Further, 79% were within ±0.50 D, and 100% were within ±1.0 D of the attempted refraction. Additionally, a 4.03%±2.2% reduction in ECD compared with the preoperative value was observed at the last follow-up visit. Changes in ECD were significantly correlated with vault, C-ICL, change in ACA and change in ACV. Vault was the most significant factor for changes in ECD.ConclusionsICL V4c implantation is safe and effective for myopia correction. Anterior segment biometric parameters including the vault, ACA and C-ICL may influence changes in ECD; specifically, the vault plays a major role.

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Section: Introductionmentioning

confidence: 99%

Four-year observation of the changes in corneal endothelium cell density and correlated factors after Implantable Collamer Lens V4c implantation

Yang

Zhao

Zhao³

et al. 2020

Br J Ophthalmol

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“…As for Healon 5 ® , randomized studies found that the postoperative IOP in Healon 5 ® -treated eyes was less than that in Viscoat ® -treated eyes at 6 hours, but was not significantly different from Viscoat ® -treated eyes at 1 day (Rainer et al 2000). Other studies found no difference in early postoperative IOP between Healon 5 ® -treated and other OVD-treated eyes (OcuCoat ® , Celoftal ® , Viscoat ® and Healon GV ® , Holzer et al 2001; Healon GV ® , Arshinoff et al 2002; Healon ® , Oshika et al 2004; Amvisc Plus ® , Moser et al 2004). No randomized studies examining the postoperative IOP increase in DisCoVisc ® – or Visthesia ® -treated eyes have been reported.…”

Section: Postoperative Complications and Ovdsmentioning

confidence: 89%

Use of viscoelastic substance in ophthalmic surgery — focus on sodium hyaluronate

Higashide

Sugiyama²

2008

OPTH

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Among viscoelastic substances, sodium hyaluronate has become the most popular for intraocular surgeries since the introduction of Healon® (sodium hyaluronate 1%, 4 × 106 daltons) in 1979. This review focuses on the recent development of a new generation of sodium hyaluronate agents with new rheologic properties and the relevant new techniques used in cataract, glaucoma, corneal, and vitreoretinal surgeries. The introduction of sodium hyaluronate agents with different rheologic properties has improved the safety and reliability of intraocular surgeries. Although there have been numerous studies reporting the effectiveness of viscoelastic substances in intraocular surgeries, rigorous validation by multi-center randomized control trials is lacking in many cases. At present, no single viscoelastic agent is most suitable to all of the various intraocular surgical techniques. Therefore, ophthalmologic surgeons should keep up with recent developments of viscoelastic agents and relevant surgical techniques for better patient care.

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“…No blinding or incomplete blinding, but the review authors judge that the outcome is not likely to be influenced by lack of blinding; blinding of participants and key study personnel ensured, and unlikely that the blinding could have been broken. [3,7,8,[10][11][12][13]18,19,21,25,27,[29][30][31][32]35,36,[38][39][40][41][42][43]46,[49][50][51][52][53][54][55][56][57]59,[63][64][65][66][67]69,70,74] High risk…”

Section: Referencesmentioning

confidence: 99%

“…Based on the literature, a minimum of 500 cells/mm 2 is required to maintain corneal transparency [35,39]. Specular microscopy is used to measure these endothelial cell parameters, but it is only effective on the central 1 mm 2 of the cornea, and it cannot be used to assess all of the corneal layers in order to determine the degree of corneal edema [13,41,42,64]. Intraoperative mechanical stress can be caused by stress and thus trauma to the corneal endothelium.…”

Section: Endothelial Cell Loss (Ecl)mentioning

confidence: 99%

Corneal Edema after Cataract Surgery

Briceno-Lopez,

Burguera-Giménez,

García-Domene

et al. 2023

JCM

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This systematic review investigates the prevalence and underlying causes of corneal edema following cataract surgery employing manual phacoemulsification. A comprehensive search encompassing databases such as PubMed, Embase, ProQuest, Cochrane Library, and Scopus was conducted, focusing on variables encompassing cataract surgery and corneal edema. Two independent reviewers systematically extracted pertinent data from 103 articles, consisting of 62 theoretical studies and 41 clinical trials. These studies delved into various aspects related to corneal edema after cataract surgery, including endothelial cell loss, pachymetry measurements, visual performance, surgical techniques, supplies, medications, and assessments of endothelial and epithelial barriers. This review, encompassing an extensive analysis of 3060 records, revealed significant correlations between corneal edema and endothelial cell loss during phacoemulsification surgery. Factors such as patient age, cataract grade, and mechanical stress were identified as contributors to endothelial cell loss. Furthermore, pachymetry and optical coherence tomography emerged as valuable diagnostic tools for assessing corneal edema. In conclusion, this systematic review underscores the link between corneal edema and endothelial cell loss in manual phacoemulsification cataract surgery. It highlights the relevance of factors like patient demographics and diagnostic modalities. However, further research is essential to unravel the complexities of refractive changes and the underlying mechanisms.

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Corneal edema and intraocular pressure after cataract surgery

Abstract: Both OVDs were beneficial in a wide range of cataract patients. However, the results suggest a tendency toward a higher complication rate with Healon5.

Cited by 6 publications

References 25 publications

Four-year observation of the changes in corneal endothelium cell density and correlated factors after Implantable Collamer Lens V4c implantation

Four-year observation of the changes in corneal endothelium cell density and correlated factors after Implantable Collamer Lens V4c implantation

Use of viscoelastic substance in ophthalmic surgery — focus on sodium hyaluronate

Corneal Edema after Cataract Surgery

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Corneal edema and intraocular pressure after cataract surgery

Abstract: Both OVDs were beneficial in a wide range of cataract patients. However, the results suggest a tendency toward a higher complication rate with Healon5.

Cited by 6 publications

References 25 publications

Four-year observation of the changes in corneal endothelium cell density and correlated factors after Implantable Collamer Lens V4c implantation

Four-year observation of the changes in corneal endothelium cell density and correlated factors after Implantable Collamer Lens V4c implantation

Use of viscoelastic substance in ophthalmic surgery&nbsp;&mdash; focus on sodium hyaluronate

Corneal Edema after Cataract Surgery

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Use of viscoelastic substance in ophthalmic surgery — focus on sodium hyaluronate