Core-Shell Nanofibers Based on Polycaprolactone/Polyvinyl Alcohol and Polycaprolactone/Collagen for Biomedical Applications

Moradipour, Pouran; Limoee, Mazdak; Janfaza, Sajjad; Behbood, Leila

doi:10.1007/s12247-021-09568-z

Cited by 8 publications

(7 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…If the surface tension is low, the formation of the jet begins at a lower voltage. The surface tension of polymer solution can be changed by varying solvents and by adding surfactants [26,41].…”

Section: Surface Tensionmentioning

confidence: 99%

“…Fourth, electrospinning enables the production of fibers with an infinite number of chemical compositions, and fifth, it also allows the production of different types of morphology by modifying the spinneret. With the combination of these properties, electrospun fibers can be utilized in biomedical applications [12,41,43,51,54,60,[77][78][79][80][81][82][83][84], filtration [39,[85][86][87][88], energy sectors [2,[89][90][91][92][93], sensors [5,26,[94][95][96][97], textiles, catalysis [26,98], and electrical applications [99,100]. Figure 7 shows the different types of nanofibers and their applications.…”

Section: Applications Of Electrospun Fibersmentioning

confidence: 99%

“…The rate and timing of drug release may be controlled by changing the fiber structure to promote effective wound healing. As a result, electrospun nanofibers have a lot of potential for developing improved bioactive wound dressings [26,41,47,49,53,54,66,77,78,98,108,110,111].…”

Section: Wound Healingmentioning

confidence: 99%

See 2 more Smart Citations

Electrospinning: The Technique and Applications

Sharma¹,

James²

2023

Recent Developments in Nanofibers Research

View full text Add to dashboard Cite

Electrospinning is a useful and convenient method for producing ultrathin fibers. It has grabbed the scientific community’s interest due to its potential to produce fibers with various morphologies. Numerous efforts have been made by researchers and industrialists to improve the electrospinning setup and the associated techniques in order to regulate the morphology of the electrospun fibers for practical applications. Porous, hollow, helical, aligned, multilayer, core-shell, and multichannel fibers have been fabricated for different applications. This chapter aims to provide readers with a clear understanding of the electrospinning process: its principle, methodology, materials, and applications. The chapter begins with a brief introduction to the history of electrospinning, followed by a discussion of its principle and the basic components of electrospinning setup. The parameters that affect the electrospinning process such as operating parameters and the properties of the material being electrospun are discussed briefly. An overview of the different types of electrospinning technique, capable of producing nanofibers with different morphologies, is also presented. Afterward, the applications of electrospun nanofibers, including their use in biomedical applications, filtration, energy sectors, and sensors applications are discussed succinctly. The perspectives on the challenges, opportunities, and new directions for future development of electrospinning technology are also offered.

show abstract

Section: Surface Tensionmentioning

confidence: 99%

Section: Applications Of Electrospun Fibersmentioning

confidence: 99%

See 1 more Smart Citation

Electrospinning: The Technique and Applications

Sharma¹,

James²

2023

Recent Developments in Nanofibers Research

View full text Add to dashboard Cite

show abstract

“…This leads to a loss of the cones' characteristic shape due to intermixing of both internal and external fluids. To ensure the consistent and uniform encapsulation of the core within the shell, it is important to maintain a lower output rate for the core solution compared to that of the shell solution [34].…”

Section: Structure and Surface Morphologymentioning

confidence: 99%

Facile Coaxial Electrospinning Synthesis of Polyacrylonitrile/Cellulose Acetate Nanofiber Membrane for Oil–Water Separations

AL-Rajabi,

Almanassra,

Khalil

et al. 2023

Polymers

View full text Add to dashboard Cite

Oil-contaminated water and industrial oily wastewater discharges have adversely affected aquatic ecosystems and human safety. Membrane separation technology offers a promising solution for effective oil–water separation. Thus, a membrane with high surface area, hydrophilic–oleophobic properties, and stability is a promising candidate. Electrospinning, a straightforward and efficient process, produces highly porous polymer-based membranes with a vast surface area and stability. The main objective of this study is to produce hydrophilic–oleophobic polyacrylonitrile (PAN) and cellulose acetate (CA) nanofibers using core–shell electrospinning. Incorporating CA into the shell of the nanofibers enhances the wettability. The core PAN polymer improves the electrospinning process and contributes to the hydrophilicity–oleophobicity of the produced nanofibers. The PAN/CA nanofibers were characterized by Fourier transform infrared spectroscopy, field emission scanning electron microscopy, X-ray diffraction, and surface-wetting behavior. The resulting PAN/cellulose nanofibers exhibited significantly improved surface-wetting properties, demonstrating super-hydrophilicity and underwater superoleophobicity, making them a promising choice for oil–water separation. Various oils, including gasoline, diesel, toluene, xylene, and benzene, were employed in the preparation of oil–water mixture solutions. The utilization of PAN/CA nanofibers as a substrate proved to be highly efficient, confirming exceptional separation efficiency, remarkable stability, and prolonged durability. The current work introduces an innovative single-step fabrication method of composite nanofibers, specially designed for efficient oil–water separation. This technology exhibits significant promise for deployment in challenging situations, offering excellent reusability and a remarkable separation efficiency of nearly 99.9%.

show abstract

“…Achieving sustained drug release using nanofibers composed of water-soluble polymer PVA is expected to be more challenging than that from nanofibers made from biodegradable hydrophobic polymers such as poly(lactic-co-glycolic acid) (PLGA) and poly(ε-caprolactone) (PCL). 8,9) Different grades of PVA having varying degrees of hydrolysis and polymerization could control the solubility of PVA nanofibers; however, there are few reports on this. By using the PVA grades, LZM release from various PVA nanofibers was evaluated in this study, as shown in Table 1.…”

Section: Introductionmentioning

confidence: 99%

Controlled Release of Lysozyme Using Polyvinyl Alcohol-Based Polymeric Nanofibers Generated by Electrospinning

Ogawa,

Hara,

Kobayashi

et al. 2024

CHEMICAL & PHARMACEUTICAL BULLETIN

View full text Add to dashboard Cite

Polymeric nanofibers generated via electrospinning offer a promising platform for drug delivery systems. This study examines the application of electrospun polyvinyl alcohol (PVA) nanofibers for controlled lysozyme (LZM) delivery. By using various PVA grades, such as the degree of polymerization/hydrolysis, this study investigates their influence on nanofiber morphology and drug-release characteristics. LZM-loaded PVA monolithic nanofibers having 50% drug content exhibit efficient entrapment, wherein rapid dissolution is achieved within 30 min. The initial burst of LZM from the nanofiber was reduced as the LZM content was lowered. The initial dissolution is greatly influenced by the choice of PVA grade used; fully hydrolyzed PVA nanofibers demonstrate controlled release due to the reduced water solubility of PVA. Furthermore, coaxial electrospinning, which creates core-shell nanofibers with polycaprolactone as a controlled release layer, enables sustained LZM release over an extended period. This study confirms a correlation between PVA characteristics and controlled drug release and provides valuable insights into tailoring nanofiber properties for pharmaceutical applications.

show abstract

Core-Shell Nanofibers Based on Polycaprolactone/Polyvinyl Alcohol and Polycaprolactone/Collagen for Biomedical Applications

Cited by 8 publications

References 23 publications

Electrospinning: The Technique and Applications

Electrospinning: The Technique and Applications

Facile Coaxial Electrospinning Synthesis of Polyacrylonitrile/Cellulose Acetate Nanofiber Membrane for Oil–Water Separations

Controlled Release of Lysozyme Using Polyvinyl Alcohol-Based Polymeric Nanofibers Generated by Electrospinning

Contact Info

Product

Resources

About