Core-shell materials, lipid particles and nanoemulsions, for delivery of active anti-oxidants in cosmetics applications: challenges and development strategies

Tran, Vinh Van; Nguyen, Tuan Loi; Moon, Ju‐Young; Lee, Young-Chul

doi:10.1016/j.cej.2019.02.168

Cited by 68 publications

(29 citation statements)

References 247 publications

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“…This passage can be favored by the active principle's affinity for the horny layer and promotes the increased penetration of lipid-soluble. The topical-based drug formulation that contains fats and/or polymers oils may also generate occlusive effects, becoming suitable for pharmaceutical and cosmetic applications (Zhai and Maibach, 2002 ; Van Tran et al, 2019 ).…”

Section: Influencing Factors That Affect the Nanoliposomes Performancmentioning

confidence: 99%

Insight Into Nanoliposomes as Smart Nanocarriers for Greening the Twenty-First Century Biomedical Settings

Aguilar-Pérez

Avilés-Castrillo

Medina

et al. 2020

Front. Bioeng. Biotechnol.

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The necessity to develop more efficient, biocompatible, patient compliance, and safer treatments in biomedical settings is receiving special attention using nanotechnology as a potential platform to design new drug delivery systems (DDS). Despite the broad range of nanocarrier systems in drug delivery, lack of biocompatibility, poor penetration, low entrapment efficiency, and toxicity are significant challenges that remain to address. Such practices are even more demanding when bioactive agents are intended to be loaded on a nanocarrier system, especially for topical treatment purposes. For the aforesaid reasons, the search for more efficient nano-vesicular systems, such as nanoliposomes, with a high biocompatibility index and controlled releases has increased considerably in the past few decades. Owing to the stratum corneum layer barrier of the skin, the in-practice conventional/conformist drug delivery methods are inefficient, and the effect of the administered therapeutic cues is limited. The current advancement at the nanoscale has transformed the drug delivery sector. Nanoliposomes, as robust nanocarriers, are becoming popular for biomedical applications because of safety, patient compliance, and quick action. Herein, we reviewed state-of-the-art nanoliposomes as a smart and sophisticated drug delivery approach. Following a brief introduction, the drug delivery mechanism of nanoliposomes is discussed with suitable examples for the treatment of numerous diseases with a brief emphasis on fungal infections. The latter half of the work is focused on the applied perspective and clinical translation of nanoliposomes. Furthermore, a detailed overview of clinical applications and future perspectives has been included in this review.

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Section: Influencing Factors That Affect the Nanoliposomes Performancmentioning

confidence: 99%

Insight Into Nanoliposomes as Smart Nanocarriers for Greening the Twenty-First Century Biomedical Settings

Aguilar-Pérez

Avilés-Castrillo

Medina

et al. 2020

Front. Bioeng. Biotechnol.

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“…Antioxidant activity is one of the most important features to evaluate the applicability of plant extracts [35,36]. Although O. humifusa contains an abundance of antioxidant components that are excellent candidates for cosmetic applications, it has not been widely applied as a cosmetic ingredient due to its high viscosity [17].…”

Section: Discussionmentioning

confidence: 99%

Effects of Microwave-Assisted Opuntia humifusa Extract in Inhibiting the Impacts of Particulate Matter on Human Keratinocyte Skin Cell

et al. 2020

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Particulate matter (PM) is one of the most important factors causing serious skin diseases, due to its generation of reactive oxygen species (ROS) over the course of long-term exposure. As a source of natural antioxidants, Opuntia humifusa (O. humifusa) is a potential candidate for the design of advanced formulations to prevent PM’s harmful effects. Unfortunately, its high viscosity does not allow it to be utilized in these formulations. In this present study, a new approach to the extract of O. humifusa using high-power microwave treatment, namely microwave-assisted O. humifusa extract (MA-OHE), was investigated. The results indicated that MA-OHE not only is a reasonable viscosity extract, but also enhances O. humifusa’s antioxidant properties. Additionally, this study also found that MA-OHE exhibited outstanding antioxidant and anti-inflammatory activities in eliminating PM’s effects, due to suppression of AhR degradation, ROS production, and COX-2 and MMP-9 expression in HaCaT keratinocytes. It is believed that MA-OHE is a potential cosmeceutical ingredient that could be utilized to prevent PM-induced skin oxidative stress and inflammation.

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“…Another strategy is the use of chemically functionalised biodegradable polymeric carriers able to give enhanced properties over conventional carrier materials with the advantage of being nonreactive when in contact with the human body and metabolised and removed from the body via normal metabolic pathways [ 33 , 195 ]. The most commonly used shell materials in cosmetics are polysaccharides (gums, starches, celluloses, CDs and chitosan) [ 196 , 197 ]; proteins (gelatin, casein and soy proteins) [ 198 ]; lipids (waxes, paraffin and oils) [ 198 , 199 ] and synthetic polymers (acrylic polymers, polyvinyl alcohol and poly(vinylpyrrolidone)) [ 15 , 200 ]. Inorganic materials (silicates, clays and polyphosphates) can also be used [ 201 ].…”

Section: Applications Of Micro-/nanoencapsulated Fragrances and Flmentioning

confidence: 99%

Encapsulation of Flavours and Fragrances into Polymeric Capsules and Cyclodextrins Inclusion Complexes: An Update

2020

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Flavours and fragrances are volatile compounds of large interest for different applications. Due to their high tendency of evaporation and, in most cases, poor chemical stability, these compounds need to be encapsulated for handling and industrial processing. Encapsulation, indeed, resulted in being effective at overcoming the main concerns related to volatile compound manipulation, and several industrial products contain flavours and fragrances in an encapsulated form for the final usage of customers. Although several organic or inorganic materials have been investigated for the production of coated micro- or nanosystems intended for the encapsulation of fragrances and flavours, polymeric coating, leading to the formation of micro- or nanocapsules with a core-shell architecture, as well as a molecular inclusion complexation with cyclodextrins, are still the most used. The present review aims to summarise the recent literature about the encapsulation of fragrances and flavours into polymeric micro- or nanocapsules or inclusion complexes with cyclodextrins, with a focus on methods for micro/nanoencapsulation and applications in the different technological fields, including the textile, cosmetic, food and paper industries.

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Core-shell materials, lipid particles and nanoemulsions, for delivery of active anti-oxidants in cosmetics applications: challenges and development strategies

Cited by 68 publications

References 247 publications

Insight Into Nanoliposomes as Smart Nanocarriers for Greening the Twenty-First Century Biomedical Settings

Insight Into Nanoliposomes as Smart Nanocarriers for Greening the Twenty-First Century Biomedical Settings

Effects of Microwave-Assisted Opuntia humifusa Extract in Inhibiting the Impacts of Particulate Matter on Human Keratinocyte Skin Cell

Encapsulation of Flavours and Fragrances into Polymeric Capsules and Cyclodextrins Inclusion Complexes: An Update

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