Core beliefs and psychological distress in patients with psoriasis and atopic eczema attending secondary care: the role of schemas in chronic skin disease

Mizara, Alexandra; Papadopoulos, Linda; McBride, Sandy

doi:10.1111/j.1365-2133.2011.10799.x

Cited by 71 publications

(78 citation statements)

References 36 publications

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“…Interestingly, atopy and depression have recently been linked. Although methodologies differ among studies, it has been consistently reported that atopic disorders are associated with an increased risk of both clinical depression and depressive symptomatology in clinical settings [160-163]. Population-based studies provide further support, showing a positive association between depression and atopic disorders [164-168].…”

Section: Introductionmentioning

confidence: 99%

So depression is an inflammatory disease, but where does the inflammation come from?

Berk

Williams

Jacka

et al. 2013

BMC Med

1,136

736

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BackgroundWe now know that depression is associated with a chronic, low-grade inflammatory response and activation of cell-mediated immunity, as well as activation of the compensatory anti-inflammatory reflex system. It is similarly accompanied by increased oxidative and nitrosative stress (O&NS), which contribute to neuroprogression in the disorder. The obvious question this poses is ‘what is the source of this chronic low-grade inflammation?’DiscussionThis review explores the role of inflammation and oxidative and nitrosative stress as possible mediators of known environmental risk factors in depression, and discusses potential implications of these findings. A range of factors appear to increase the risk for the development of depression, and seem to be associated with systemic inflammation; these include psychosocial stressors, poor diet, physical inactivity, obesity, smoking, altered gut permeability, atopy, dental cares, sleep and vitamin D deficiency.SummaryThe identification of known sources of inflammation provides support for inflammation as a mediating pathway to both risk and neuroprogression in depression. Critically, most of these factors are plastic, and potentially amenable to therapeutic and preventative interventions. Most, but not all, of the above mentioned sources of inflammation may play a role in other psychiatric disorders, such as bipolar disorder, schizophrenia, autism and post-traumatic stress disorder.

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Section: Introductionmentioning

confidence: 99%

So depression is an inflammatory disease, but where does the inflammation come from?

Berk

Williams

Jacka

et al. 2013

BMC Med

1,136

736

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“…One study showed that patients with acne or psoriasis were more depressed and had more frequent suicidal thoughts compared with those with eczema (6). On the other hand, Mizara et al (23) did not find any significant difference in levels of depression or anxiety between people with psoriasis and those with eczema. There are also studies in which no significant differences were found in levels of depression and anxiety between people with skin conditions and healthy subjects (24).…”

mentioning

confidence: 97%

Quality of Life and Emotional State in Chronic Skin Disease

Pärna¹,

Aluoja²,

Kingo³

2015

Acta Derm Venerol

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The aim of this study was to evaluate the associations between chronic inflammatory skin conditions and patients' emotional state and quality of life. The following self-rated questionnaires were used: Emotional State Questionnaire, a self-report scale assessing depression and anxiety symptoms; Dermatology Life Quality Index (DLQI); and RAND-36, a measure of health-related quality of life. The study group comprised 40 patients with psoriasis, 40 with eczema, 40 with acne, 15 with seborrhoeic dermatitis and 40 healthy controls. Patients with chronic skin diseases had lower DLQI and lower RAND-36 physical functioning scores, more perceived physical limitations and pain, and lower emotional well-being and general health ratings compared with the control group. In conclusion, chronic skin diseases are associated with symptoms of emotional distress, in particular insomnia and general anxiety.

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“…Por fim, há que considerar as perturbações da ansiedade secundárias ao impacto social de ter uma dermatose crónica e ainda a presença, caracterís-tica nestes doentes, de esquemas mal-adaptativos precoces e alexitimia, que podem também contribuir para explicar a elevada prevalência de perturbações da ansiedade nos doentes com psoríase. 12,13 Os resultados mostraram uma associação estatisticamente significativa entre o grupo de doentes com psoríase e o consumo de antipsicóticos, sobretudo tiaprida. Este fár-maco é frequentemente prescrito a doentes com diagnóstico de perturbação relacionada com o consumo de álcool com seguimento em Psiquiatria.…”

Section: Discussionunclassified

Psoríase, Psicofármacos e Comorbilidades Psiquiátricas: Um Estudo de Caso-Controlo numa População de Doentes Hospitalizados

Ferreira

Santiago

Simões

et al. 2017

SPDV

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RESUMO -Introdução:A psoríase é uma dermatose inflamatória crónica com impacto significativo na qualidade de vida e múltiplas comorbilidades, com reconhecimento classicamente atribuído aos fatores de risco cardiovascular. Recentemente tem-se destacado a relação com as comorbilidades psiquiátricas. Material e Métodos: Estabeleceu-se como objetivo primá-rio avaliar a prevalência de psicofármacos na medicação habitual dos doentes hospitalizados com o diagnóstico de psoríase. Realizou-se um estudo de caso-controlo no Serviço de Dermatologia do Centro Hospitalar e Universitário de Coimbra, entre 2010 e 2015, partindo da medicação habitual. Os fármacos foram agrupados pela classificação do INFARMED. Definiram--se como objetivos secundários comparar a prevalência de fármacos para tratamento de fatores de risco cardiovascular nos dois grupos e reunir informação sobre comorbilidades psiquiátricas disponível nos processos clínicos dos doentes hospitalizados com psoríase. A análise estatística foi realizada recorrendo ao software STATA 14 e a significância estatística foi definida para p<0,05. Resultados: O grupo com psoríase era constituído por 79 doentes, 67% do sexo masculino, 33% do sexo feminino e idade média de 59,30±17,17 anos. Observou-se uma associação entre psoríase e consumo de fármacos do sistema nervoso central, particularmente psicofármacos, sobretudo ansiolíticos e antipsicóticos (p<0,01), com 63% dos doentes medicados com pelo menos um psicofármaco. Verificou-se também associação entre psoríase e medicação regular com anti-hipertensores (p<0,05). A referência a diagnósticos psiquiátricos nos processos clínicos era, frequentemente, imprecisa ou inexistente. Conclusão: Os resultados salientam o peso do consumo de psicofármacos e reforçam estudos prévios sobre a subavaliação em psicopatologia dos doentes com psoríase. Salienta-se a importância da avaliação holística nas patologias da psicodermatologia. PALAVRAS-CHAVE -

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Core beliefs and psychological distress in patients with psoriasis and atopic eczema attending secondary care: the role of schemas in chronic skin disease

Cited by 71 publications

References 36 publications

So depression is an inflammatory disease, but where does the inflammation come from?

So depression is an inflammatory disease, but where does the inflammation come from?

Quality of Life and Emotional State in Chronic Skin Disease

Psoríase, Psicofármacos e Comorbilidades Psiquiátricas: Um Estudo de Caso-Controlo numa População de Doentes Hospitalizados

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