“…This difference can be harmful for people that need protein ingested in food and water is relatively low, and most humans and animals are able to control excessive amounts of copper in the body by either decreased absorption or increased excretion (GAETKE;CHOW, 2003). An extremely large amount of orally ingested copper (0.07 mg/kg per day) has been associated with adverse gastrointestinal effects (SHILS et al, 2003).…”
“…This difference can be harmful for people that need protein ingested in food and water is relatively low, and most humans and animals are able to control excessive amounts of copper in the body by either decreased absorption or increased excretion (GAETKE;CHOW, 2003). An extremely large amount of orally ingested copper (0.07 mg/kg per day) has been associated with adverse gastrointestinal effects (SHILS et al, 2003).…”
“…and then oxidative stress. Previously reported, exposure to excessive Cu ions leads to generation of oxidative stress in plant system (Gaetke and Chow, 2003). A suggested strategy to avoid toxicity of heavy metals is through the induction of antioxidant enzyme system and increase in the non-enzymatic antioxidants to reduce the oxidative damage related to excessive ROS formation caused by heavy metals (Verma and Dubey, 2003).…”
“…[5,8]. Стосовно Купруму, слід наголосити, що, володіючи високим окисно-відновним потенціа лом, цей метал служить кофактором протеїнів у різних біологічних реакціях і процесах, таких як дихання, формування сполучної тканини, обміні Феруму, знешкодженні вільних радикалів, бере участь у неврологічних функціях [9][10].…”
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