Copper(ii) salen-based complexes as potential anticancer agents

Abstract

The systematic design and synthesis of four Cu(ii) salen compounds and their potential as excellent anticancer agents is discussed using biological studies.

Transition metal complexes as self-activating chemical nucleases: proficient DNA cleavage without any exogenous redox agents

“…Salen-based metal complexes are well known to display excellent nuclease activity; 128,129 however, only a few complexes are reported as self-activating chemical nucleases.…”

A novel Salen-based dual channel sensor for easy and selective nanomolar detection of l-cysteine

“…Among the multitude of reported sensors, Schiff bases stand out due to their straightforward synthesis, easy isolation, and rapid complexation. 31 The aforementioned attributes of Schiff bases make them good candidates for several application studies. [32][33][34][35] There are also a lot of reports on the use of these species as sensors for various purposes.…”

“…31 The aforementioned attributes of Schiff bases make them good candidates for several application studies. [32][33][34][35] There are also a lot of reports on the use of these species as sensors for various purposes. For instance, in the study done by Nandhakumar et al, 36 they synthesized a S-S bridged dimeric Schiff base, which is used for the selective nanomolecular detection of Fe 2+ and Al 3+ .…”