Copper kinetics and internal distribution in the marbled crayfish (Procambarus sp.)

Soedarini, Bernadeta; Klaver, L.; Roessink, Ivo; Widianarko, Budi; Straalen, Nico M. van; Gestel, Cornelis A.M. van

doi:10.1016/j.chemosphere.2011.12.017

Cited by 28 publications

(35 citation statements)

References 42 publications

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“…The highest correlations are between gill and the exoskeleton, and both tissues are connected to the external environment. In addition, both tissues were previously reported as sites of high Cu biosorption (Soedarini et al 2012).…”

Section: Correlation Trends Of the Same Metal And Metalloid In Differmentioning

confidence: 96%

Tissue Distribution and Correlation Profiles of Heavy-Metal Accumulation in the Freshwater Crayfish Astacus leptodactylus

Tunca

Üçüncü

Özkan

et al. 2013

Arch Environ Contam Toxicol

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The present work details the analysis of heavymetal and metalloid concentrations in exoskeleton, gill, hepatopancreas, and abdominal muscle tissues of 60 crayfish (Astacus leptodactylus) specimens collected from Lake Hirfanlı, a dam lake located in Kırşehir (Turkey) with a low metal-contamination profile. [Pb]) and a metalloid (arsenic [As]) were measured by inductively coupled plasma-mass spectrometry, and the relative frequencies of the most abundant isotopes of Cr, Cu, Ag, Cd, Hg, and Pb were evaluated. Three correlation trends were evaluated between the following: (1) different elements in the each individual tissue, (2) individual elements in different tissues, and (3) different elements in different tissues. In addition, correlation rates of growth parameters (weight, cephalothorax length, and total length) with heavy-metal and metalloid concentrations in each tissue were investigated. Our results suggest that substantial differences in metal and metalloid-accumulation levels exist between male and female specimens, with stronger correlations between the heavy-metal concentrations observed in the male cohort. It is notable that correlation trends of Co, Cu, 52 As, Cr, and Ni in exoskeleton of the male specimens display strong similarities. Likewise, a very strong correlation is present in Ni-Cd and Ni-Pb accumulations in abdominal muscle of the male specimens; a similar trend is present between Cd and Pb concentrations in the same tissue of female specimens. For correlation rates of different heavy metals and metalloid in different tissues, the strongest positive association observed was between 63 Cu in gill and As in hepatopancreas, whereas the strongest negative correlation was between accumulated Ni in abdominal muscle and As in exoskeleton. Strong correlations between metals and metalloid accumulations were observed between exoskeleton and gill. In many cases, metal and metalloid accumulation was negatively correlated with growth parameters. Preferential accumulation of Cr and Cu isotopes was observed in different tissues, suggesting that significant amounts of isotope fractionation occur during heavy-metal accumulation. Relatively low correlation rates were observed between 52 Cr/ 53 Cr and 63 Cu/ 65 Cu concentrations in several tissue types in both male and female cohorts, whereas no such trend was observed between Cd and Pb isotopes.

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Section: Correlation Trends Of the Same Metal And Metalloid In Differmentioning

confidence: 96%

Tissue Distribution and Correlation Profiles of Heavy-Metal Accumulation in the Freshwater Crayfish Astacus leptodactylus

Tunca

Üçüncü

Özkan

et al. 2013

Arch Environ Contam Toxicol

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“…Data on measured copper concentrations in the water, crayfish growth and copper uptake and elimination kinetics have been reported by Soedarini et al (2012) and are summarized here. Average measured copper concentrations in the water during the first 14-day test period were 0.031 mg Cu/1 and 0.38 mg Cu/1, respectively.…”

Section: Resultsmentioning

confidence: 99%

“…Exposure solutions and animal organs were analysed for copper concentrations as described by Soedarini et al (2012).…”

Section: Copper Exposurementioning

confidence: 99%

“…In a previous study (Soedarini et al, 2012), marbled crayfish showed accumulation of copper in different tissues at increased exposure concentrations in the water with excess copper especially being stored in the hepatopancreas. The pattern of copper bioaccumulation in crayfish is similar to that in other aquatic crustaceans, such as the penaeid shrimp Metapenaeus dobsoni (Manisseri and Menon, 1995), the blue crab Callinectes spp.…”

Section: Introductionmentioning

confidence: 97%

See 1 more Smart Citation

Effect of copper exposure on histamine concentrations in the marbled crayfish (Procambarus fallax forma virginalis)

Soedarini¹,

Klaver

Giesen³

et al. 2013

Animal Biol

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Crustaceans can store excess copper in the hepatopancreas, an organ playing a role in digestive activity as well as in neurosecretory control. Here, we studied the effect of copper exposure on the level of histamine, an indicator of food spoilage in edible crustaceans. Histamine is also a neuromodulator in the intestinal nervous system of crustaceans, and a human allergen. Marbled crayfish {Procambarus fallax forma virginalis) were exposed to average measured values of 0.031 mg Cu/1 and 0.38 mg Cu/1, respectively, for 14 days and then transferred to copper-free water for another 14 days. Concentrations of copper and histamine in the hepatopancreas and muscle were evaluated at different time points. Histamine levels were significantly higher in hepatopancreas and muscle tissues at the highest exposure level, but only after transfer of the animals to copper-free water. The increased histamine concentration following copper exposure may be explained by a (delayed) stress response, and by up-regulated histidine synthesis induced by copper, followed by decarboxylation to histamine.

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“…Shaw et al (2012) and Isani et al (2013) indicated that gill and liver of rainbow trout were the target organs for accumulating CuNP. De Boeck et al (2003), Peyghan et al (2003), and Soedarini et al (2012) pointed out that liver was the key site for homeostasis of accumulating Cu. However, gill could uptake higher CuNP levels than liver (Griffitt et al, 2007;Zhao et al, 2011).…”

Section: Modeling Of Subcellular Partitioningmentioning

confidence: 99%

Toxicokinetic Modeling Challenges for Aquatic Nanotoxicology

Chen

2016

Front. Mar. Sci.

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Nanotoxicity has become of increasing concern since the rapid development of metal nanoparticles (NPs). Aquatic nanotoxicity depends on crucial qualitative and quantitative properties of nanomaterials that induce adverse effects on subcellular, tissue, and, organ level. The dose-response effects of size-dependent metal NPs, however, are not well investigated in aquatic organisms. In order to determine the uptake and elimination rate constants for metal NPs in the metabolically active/detoxified pool of tissues, a one-compartmental toxicokinetic model can be applied when subcellular partitioning of metal NPs data would be available. The present review is an attempt to describe the nano-characteristics of toxicokinetics and subcellular partitioning on aquatic organisms with the help of the mechanistic modeling for NP size-dependent physiochemical properties and parameters. Physiologically-based pharmacokinetic (PBPK) models can provide an effective tool to estimate the time course of NP accumulation in target organs and is useful in quantitative risk assessments. NP accumulation in fish should take into account different effects of different NP sizes to better understand tissue accumulative capacities and dynamics. The size-dependent NP partition coefficient is a crucial parameter that influences tissue accumulation levels in PBPK modeling. Further research is needed to construct the effective systems-level oriented toxicokinetic model that can provide a useful tool to develop quantitatively the robustly approximate relations that convey a better insight into the impacts of environmental metal NPs on subcellular and tissue/organ responses in aquatic organisms.

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Copper kinetics and internal distribution in the marbled crayfish (Procambarus sp.)

Cited by 28 publications

References 42 publications

Tissue Distribution and Correlation Profiles of Heavy-Metal Accumulation in the Freshwater Crayfish Astacus leptodactylus

Tissue Distribution and Correlation Profiles of Heavy-Metal Accumulation in the Freshwater Crayfish Astacus leptodactylus

Effect of copper exposure on histamine concentrations in the marbled crayfish (Procambarus fallax forma virginalis)

Toxicokinetic Modeling Challenges for Aquatic Nanotoxicology

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