Copper(II) Schiff Base Complexes with Catalyst Property: Experimental, Theoretical, Thermodynamic and Biological Studies

Abstract

Two novel copper(II) Schiff base complexes were synthesized and characterized by various physico-chemical and spectroscopic methods, revealing a distorted square planar geometry around the copper atom. The analytical data confirmed the 1:1 metal to ligand stoichiometry of the complexes. B3LYP/(LANL2DZ/6-311G**) density functional theory (DFT) were used to investigate structural and electronic properties of the synthesized compounds in gas phase. The computational results support the conclusion obtained by the experimental studies. Thermodynamic study of complex formation in solution was carried out spectrophotometrically at 25 °C. These compounds were also subjected to study in vitro antibacterial screening against some bacteria. Also, click reaction was investigated for its catalytic properties. The synthesized Schiff base copper complexes catalyzed 1,3-dipolar Huisgen cycloaddition of different functionalized ?-azido alcohols and alkynes in the presence of ascorbic acid in a solution of THF/H2O (2:1, V/V) at room temperature.

Preparation and Diagnostics of Schiff Base Complexes and Thermodynamic Study for Adsorption of Cobalt Complex on Iraqi Attapulgite Clay Surface

“…Where T the absolute temperature, R is gas constant, Keq is the equilibrium constant, qe is the amount of adsorbent (mg/g), and Ce is the concentration of the remaining substance in the solution (mg/L), V is the volume of cobalt complex(L), and m is the mass of clay used (g) 31,32 .…”

Square Planar trans‐N2O2 Cu(II) Complex: Synthesis, Crystal Structure, Hirshfeld Surface, DFT, Antimicrobial and Docking Studies

“…Owing to their preparative accessibility and chelating ability to form a stable coordination complex attracts the scientific community. The chelation between N and O donor groups offers tuneable properties such as chemical, optical, electrical and biological properties [3][4][5][6][7][8] of the metal complex. The appropriate selection of primary amines with aldehydes or ketones offers various dative bonding possibilities to metal ions.…”

New copper(II) and zinc(II) complexes based on azo Schiff base ligand: Synthesis, crystal structure, photoisomerization study and antibacterial activity

“…[31][32][33][34][35] Among these, Schiff base complexes of copper and zinc, which are essential elements for humans with their several biological activities, are of paramount scientific interest. [36][37][38][39][40][41][42] In this paper, we report the synthesis of new zinc(II) and copper(II) complexes containing an azo Schiff base ligand (L) obtained by condensation of 2-hydroxy-5-(tolyldiazenyl)benzaldehyde and propylamine. X-ray crystallographic analysis of complexes [Zn(L) 2 ] and [Cu(L) 2 ] revealed the coordination sites of the ligand and also the configuration of the azo and azomethine units.…”

“…In coordination chemistry, Schiff bases constitute privileged ligands that can form stable complexes with transition metals . Among these, Schiff base complexes of copper and zinc, which are essential elements for humans with their several biological activities, are of paramount scientific interest …”