2006
DOI: 10.3390/11110904
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Copper(II) Complexes with Ligands Derived from 4-Amino-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one: Synthesis and Biological Activity

Abstract: Abstract:The synthesis of Cu(II) complexes derived from Schiff base ligands obtained by the condensation of 2-hydroxybenzaldehyde or terephtalic aldehyde with 4-aminoantipyrine (4-amino-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one) is presented.

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Cited by 81 publications
(49 citation statements)
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“…-1 in the spectra of the complexes, which confirms the coordination of the nitrogen atom to the metallic ion 25 . The presence of broad band for Cu(II) and Ni(II) complexes in the range 3500-3400 cm −1 indicates the coordination to water molecule/s.…”
Section: Infrared Spectrasupporting
confidence: 55%
“…-1 in the spectra of the complexes, which confirms the coordination of the nitrogen atom to the metallic ion 25 . The presence of broad band for Cu(II) and Ni(II) complexes in the range 3500-3400 cm −1 indicates the coordination to water molecule/s.…”
Section: Infrared Spectrasupporting
confidence: 55%
“…Treatment options for multi-drug resistant Acinetobacter spp. have been reviewed (Hartzell et al, 2007;Peleg, 2007;Gilad and Carmeli, 2008) and the potential of using other types of anti-microbials exists, for example, peptides (Knoetze et al, 2008) or copper complexed with organic compounds (Rosu et al, 2006).…”
Section: Resistance To Antibiotics and Other Anti-microbialsmentioning
confidence: 99%
“…Treatment options for multi-drug resistant Acinetobacter spp. have been reviewed (Hartzell et al, 2007;Peleg, 2007;Gilad and Carmeli, 2008) and the potential of using other types of anti-microbials exists, for example, peptides (Knoetze et al, 2008) or copper complexed with organic compounds (Rosu et al, 2006).In addition to antibiotic resistance, the importance of resistance to disinfectants or enhanced virulence due to specific disinfectants must also be considered, as discussed in section 23.Members of the Acinetobacter genus develop antibiotic resistance extremely rapidly, which has been proposed as a consequence of long-term evolutionary exposure to antibiotic-producing organisms in soil (Van Looveren and Goossens, 2004). Several intrinsic resistance genes were described in environmental strains (Agerso and Guardabassi, 2005;Messi et al, 2005) and human commensal strains (section 14.4).…”
mentioning
confidence: 99%
“…The antibacterial properties of the metal complexes and their potential for pharmacological application have been well reported [4][5][6]9,11,15]. The nickel-tetraaza complex has also been found to catalyse the division of DNA molecules [1].…”
Section: Introductionmentioning
confidence: 99%