This paper reports the synthesis and characterization of transition metal complexes of newly synthesized 2,5-substituted-1,3,4-oxadiazoles with Cu(II), VO(IV), Ni(II), Zn(II) and Cd(II). The characterization of complexes were done by elemental analysis, UV-Vis, IR, ESR methods as well as the electrical conductance, magnetic susceptibility and thermal studies. The thermal behaviour provided confirmation of the complex composition as well as the number and the nature of water molecules and the intervals of thermal stability. The in vitro qualitative and quantitative antimicrobial activity assay of all the complexes was carried out.
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