Copper(I) nitrato and nitrate complexes

Jardine, F. H.; Vohra, Anil; Young, Fudah

doi:10.1016/0022-1902(71)80056-8

Cited by 47 publications

(9 citation statements)

References 6 publications

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“…The progress of the reaction can readily be checked by TLC on silica gel and is indicated by the formation of a colourless precipitate of NEt 3 ⋅HCl, which is almost insoluble in acetone. We have relied on the use of the stable starting materials [RuHCl(CO)(PPh 3 ) 3 ] and [Cu(CH 3 COO)(PPh 3 ) 2 ] for the synthesis of ruthenium(II)/copper(I) complexes. The reaction of H 2 L 1 with ruthenium(II) precursor [RuHCl(CO)(PPh 3 ) 3 ] affords complex 1 of the type [Ru(L 1 )(CO)(PPh 3 ) 2 ] in which the ligand coordinates in tridentate ONS mode.…”

Section: Resultsmentioning

confidence: 99%

Solvent‐assisted formation of ruthenium(II)/copper(I) complexes containing thiourea derivatives: Synthesis, crystal structure, density functional theory, enzyme mimetics and in vitro biological perspectives

Vijayan

Viswanathamurthi

Sugumar

et al. 2016

Applied Organom Chemis

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N,N-[(diethylamino)(thiocarbonyl)]-substituted benzamidine ligands have been synthesized from the reaction of N,N-[(diethylamino)(thiocarbonyl)]benzimidoyl chloride with functionalized amines such as 2-aminophenol and 2-picolylamine. The reaction of N,N-[(diethylamino)(thiocarbonyl)]-2-hydroxyphenylbenzamidine (H 2 L 1 ) with ruthenium(II) precursor [RuHCl(CO)(PPh 3 ) 3 ] afforded complex 1 of the type [Ru(L 1 )(CO)(PPh 3 ) 2 ] in which the ligand coordinated in tridentate ONS mode. The reaction of H 2 L 1 with copper precursor [Cu(CH 3 COO)(PPh 3 ) 2 ] induced C═N bond cleavage of the ligand and afforded complex 3 of the type [Cu(1,1-DT) (Cl)(PPh 3 ) 2 ] (1,1-DT = 1,1-diethylthiourea) in which the ligand coordinated in a monodentate fashion. The ligand N,N-[(diethylamino)(thiocarbonyl)]-2picolylbenzamidine (HL 2 ) reacted with ruthenium(II) and copper(I) precursors to form complex 2 of the type [Ru(1,1-DT)(Cl 2 )(CO)(PPh 3 ) 2 ] and complex 3, respectively, in which the ligand underwent C═N cleavage and coordinated in a monodentate fashion via C═S group. In complexes 1 and 2, the two triphenylphosphine co-ligands coordinated in trans position whereas, in complex 3, the two triphenylphosphine co-ligands coordinated in cis position. All the compounds were characterized using infrared, UV-visible, ( 1 H, 13 C, 31 P) NMR, ESI-MS and elemental analyses. The molecular structures of ligand H 2 L 1 and complexes 1-3 were determined using X-ray crystallography, which confirmed the coordination mode of the ligands with metals. The crystal structure of complexes 1 and 2 revealed a distorted octahedral geometry around the ruthenium ion and the structure of complex 3 indicated a tetrahedral geometry around the copper ion. With the X-ray structures, density functional theory computations were carried out to determine the electronic structure of the compounds. The interactions of complexes 1-3 with calf thymus DNA and bovine serum albumin protein were investigated using UV-visible and fluorescence spectroscopic and viscometric methods. Catecholase-and phosphatase-like activities promoted by complexes 1-3 under physiological conditions have been studied. In vitro anticancer activities have been demonstrated by MTT assay, acridine orange/ethidium bromide and diamidino-2-phenylindole staining against various cancerous cell lines.

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Section: Resultsmentioning

confidence: 99%

Solvent‐assisted formation of ruthenium(II)/copper(I) complexes containing thiourea derivatives: Synthesis, crystal structure, density functional theory, enzyme mimetics and in vitro biological perspectives

Vijayan

Viswanathamurthi

Sugumar

et al. 2016

Applied Organom Chemis

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“…Synthesis procedures: 1:1 molar ratio copper complex:polypyridine ligand, dichloromethane, room temperature, and 1 h of reaction. Complex 1 was previously reported; 15 however, the synthetic method used here was different from that one. known DNA intercalator agents) and triphenylphosphine as the auxiliary ligand into the coordination sphere of copper(I).…”

Section: ■ Introductionmentioning

confidence: 99%

“…Synthesis procedures: 1:1 molar ratio copper complex:polypyridine ligand, dichloromethane, room temperature, and 1 h of reaction. Complex 1 was previously reported; however, the synthetic method used here was different from that one.…”

Section: Introductionmentioning

confidence: 99%

Copper(I)–Phosphine Polypyridyl Complexes: Synthesis, Characterization, DNA/HSA Binding Study, and Antiproliferative Activity

et al. 2017

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A series of copper(I)-phosphine polypyridyl complexes have been investigated as potential antitumor agents. The complexes [Cu(PPh)dpq]NO (2), [Cu(PPh)dppz]NO (3), [Cu(PPh)dppa]NO (4), and [Cu(PPh)dppme]NO (5) were synthesized by the reaction of [Cu(PPh)NO] with the respective planar ligand under mild conditions. These copper complexes were fully characterized by elemental analysis, molar conductivity, FAB-MS, and NMR, UV-vis, and IR spectroscopies. Interactions between these copper(I)-phosphine polypyridyl complexes and DNA have been investigated using various spectroscopic techniques and analytical methods, such as UV-vis titrations, thermal denaturation, circular dichroism, viscosity measurements, gel electrophoresis, and competitive fluorescent intercalator displacement assays. The results of our studies suggest that these copper(I) complexes interact with DNA in an intercalative way. Furthermore, their high protein binding affinities toward human serum albumin were determined by fluorescence studies. Additionally, cytotoxicity analyses of all complexes against several tumor cell lines (human breast, MCF-7; human lung, A549; and human prostate, DU-145) and non-tumor cell lines (Chinese hamster lung, V79-4; and human lung, MRC-5) were performed. The results revealed that copper(I)-phosphine polypyridyl complexes are more cytotoxic than the corresponding planar ligand and also showed to be more active than cisplatin. A good correlation was observed between the cytostatic activity and lipophilicity of the copper(I) complexes studied here.

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“…Molecular precursors based on triphenylphosphine were used for the preparation of silver and copper nanoparticles. Triphenylphosphine complexes were studied in the 1960s and 1970s, , but they have only recently been used as molecular precursors for nanoparticle synthesis. Although bis(triphenylphosphine)silver(I) myristate and Cu(I) triphenylphosphine derivatives of ethylene glycol carboxylates , have been used for the preparation of nanoparticles of individual metals, triphenylphosphine carboxylate complexes have not been previously used in the synthesis of bimetallic nanoalloys.…”

Section: Introductionmentioning

confidence: 99%

Morphology Control in AgCu Nanoalloy Synthesis by Molecular Cu(I) Precursors

et al. 2019

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As nanoparticle preparation methods employing bottom-up procedures rely on the use of molecular precursors, the chemical composition and bonding of these precursors have a decisive effect on nanoparticle formation and their resulting morphology and properties. We synthesized the Cu(I) complexes [Cu(PPh3)2(bea)] (1, bea = benzoate) and [Cu(PPh3)3(Hphta)] (2, phta = phthalate) by reducing the corresponding Cu(II) mono- and dicarboxylates with triphenylphosphine. We characterized 1 and 2 by single-crystal X-ray diffraction analysis, elemental analyses, infrared and nuclear magnetic resonance spectroscopy, and mass spectrometry and obtained complete information about their structures in the solid state and in solution. Also, we examined their thermal stability in oleylamine and determined their decomposition temperatures to be used as the minimal reaction temperature in metal nanoparticle synthesis. The complexes 1 and 2 differ in the number of reducing PPh3 ligands and the strength of carboxylate bonding to the Cu(I) center. Therefore, we employed them in combination with [Ag(NH2C12H25)2]NO3 as molecular precursors in the solvothermal hot injection synthesis of AgCu nanoalloys in oleylamine and demonstrated their influence on the elemental distribution, phase composition, particle size distribution, shape, morphology, and optical properties of the resulting nanoparticles. The nanoalloy particles from the benzoate complex 1 were oblate and polydisperse and exhibited two surface plasmons at 393 and 569 nm, which is caused by their Janus-type structure. The nanoparticles prepared from the phthalate complex 2 were round and monodisperse and exhibited one plasmon at 413 nm, as they formed an AgCu solid solution with a random distribution of the elements in a particle.

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Copper(I) nitrato and nitrate complexes

Cited by 47 publications

References 6 publications

Solvent‐assisted formation of ruthenium(II)/copper(I) complexes containing thiourea derivatives: Synthesis, crystal structure, density functional theory, enzyme mimetics and in vitro biological perspectives

Solvent‐assisted formation of ruthenium(II)/copper(I) complexes containing thiourea derivatives: Synthesis, crystal structure, density functional theory, enzyme mimetics and in vitro biological perspectives

Copper(I)–Phosphine Polypyridyl Complexes: Synthesis, Characterization, DNA/HSA Binding Study, and Antiproliferative Activity

Morphology Control in AgCu Nanoalloy Synthesis by Molecular Cu(I) Precursors

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