Copper complexes for the promotion of iminopyridine ligands derived from β-alanine and self-aldol additions: relaxivity and cytotoxic properties

Abstract

The template effect in K2 (N,O) chelated Cu(ii) complexes can promote C–C or C–N coupling products.

Synthesis and structural, magnetic and spectroscopic characterization of iron(iii) complexes with in situ formed ligands from methyl-2-pyridyl ketone transformations

“…So far, six new ligands have been reported in the literature as a result of pyCOMe transformations, which probably occur after its complexation around the metal ions. 1,13,14,[16][17][18][19][20] Attempts to synthesize the new ligands in the absence of the metal ions, under strongly basic conditions, by varying several reaction parameters (e.g. reaction times, temperatures, solvents, reactant ratios and concentrations of the reaction solutions) have failed.…”

“…15 Interesting in situ transformations of pyCOMe were observed in [Cu II 2 {pyCOCH 2 C(CH 3 )(OH)py} 2 ](ClO 4 ) 2 and [Cu II 4 {pyCOCH 2 C (CH 3 )(O)py} 2 Cl 4 ]. 13,14 The heptanuclear complex [Co III Co II 6 (OH) 6 {pyC (CH 3 )(O)CH 2 COCH 3 } 6 ](ClO 4 ) 3 contains another in situ formed ligand from the nucleophilic addition of the carbanion CH 3 COCH 2 − to pyCOMe. The carbanion is formed from the acetone solution due to the presence of the strong base NBu n 4 OMe in the reaction.…”

“…The coordination chemistry of pyCOMe with transition metal ions has been also investigated in detail and yielded complexes which contain the ligand in its present form, such as the mononuclear [M II ( pyCOMe) 2 (H 2 O) 2 ](NO 3 ) 2 (M II = Co, Ni, Cd), 12 [Cu I ( pyCOMe) 2 ] (ClO 4 ), 13 and [Cu II ( pyCOMe) 2 Cl 2 ], 14 and the coordination polymer [Mn II (N 3 ) 2 ( pyCOMe)] n with 3D diamandoid network. 15 Interesting in situ transformations of pyCOMe were observed in [Cu II 2 {pyCOCH 2 C(CH , where L′ is the zwitterionictype molecule 3-hydroxy-1-methyl-3-( pyridine-2-yl)-3H-indolizin-4-ium.…”

“…13,14 The heptanuclear complex [CoIII Co II 6 (OH) 6 {pyC (CH 3 )(O)CH 2 COCH 3 } 6 ] (ClO 4 ) 3 contains another in situ formed ligand from the nucleophilic addition of the carbanion CH 3 COCH 2 − to pyCOMe. The carbanion is formed from the acetone solution due to the presence of the strong base NBu n 4 OMe in the reaction.…”

Synthesis and spectroscopic study of new ligand 3-(acetylthioureido)propanoic acid with their metal complexes

“…Metal-oxygen and metal-nitrogen bonds are confirmed by the presence of the stretching vibration of ν(M-O) and ν(M-N) around (501-451)cm -1 and (470-405)cm -1 respectively (17) .Table (4) describes the important bands and assignment for free ligand (ATA) and its complexes. (20) , all data are indicated in the Table (1).…”