Copper-azide nanoparticle: a ‘catalyst-cum-reagent’ for the designing of 5-alkynyl 1,4-disubstituted triazoles

Abstract

A single pot, wet chemical route has been applied for the synthesis of polymer supported copper azide, CuN3, nanoparticles (CANP). The hybrid system was used as ‘catalyst-cum-reagent’ for the azide-alkyne cyclo-addition reaction to construct triazole molecules using substituted benzyl bromide and terminal alkyne. The electron donating group containing terminal alkyne produced 5-alkynyl 1,4-disubstituded triazole product whereas for alkyne molecule with terminal electron withdrawing group facilitate the formation of 1,4-disubstituted triazole molecule.

Recent Progress of Metal Nanoparticle Catalysts for C–C Bond Forming Reactions

“…Substrate-dependent chemodivergent was also observed in the reaction of substituted benzyl bromides with terminal alkynes catalyzed by CuN 3 NPs. The electron donating group containing terminal alkyne produced 5-alkynyl 1,4-disubstituted triazoles whereas for alkynes with terminal electron withdrawing group facilitated the formation of 1,4-disubstituted triazoles (Scheme 32) [330]. The synthesis of 3-substituted isocoumarins from 2-chlorobenzoic acids and 1,3-diketones have been achieved utilizing Cu NPs.…”

Electrical response of organic molecule supported preformed and in situ formed antimony sulfide nanoparticles under frequency conditions

“…Organic-inorganic hybrid system have received extensive attention for wide range of applications, such as energy storage, chemical sensor and catalysis. [1][2][3] The hybrid material represents the interface between two separate dimensions of materials that can demonstrate better properties compared with their individuals. The system acquires good stability and different physical properties from the inorganic counterpart and easy processing and flexibility from the organic counterpart.…”