1992
DOI: 10.1016/0098-1354(92)80038-b
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Coordinated design and control optimization of nonlinear processes

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Cited by 101 publications
(54 citation statements)
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“…When analyzing the reactor alone, Agrawal et al identified regimes of hysteresis and periodic operation. In the design study, Brengel and Seider (1991) maximized the venture profit of the flowsheet by adjusting the design variables (h, X , S , a, F, F,, F,, and R). When y = 0.4 and /3 = 0.1, the maximum venture profit was located at Da = 0.5597, an unstable steady state.…”
Section: Successive Continuationmentioning
confidence: 99%
See 1 more Smart Citation
“…When analyzing the reactor alone, Agrawal et al identified regimes of hysteresis and periodic operation. In the design study, Brengel and Seider (1991) maximized the venture profit of the flowsheet by adjusting the design variables (h, X , S , a, F, F,, F,, and R). When y = 0.4 and /3 = 0.1, the maximum venture profit was located at Da = 0.5597, an unstable steady state.…”
Section: Successive Continuationmentioning
confidence: 99%
“…In one approach, Brengel and Seider (1991) present a strategy for evaluating the MPC performance as the design optimization proceeds. In a prototype computing system, PRODOC, they simulate several disturbance scenarios and penalize the design objective for poor controllability, which results in decreased profitability due to offspec production.…”
Section: Coordination Of Design and Control Optimizationsmentioning
confidence: 99%
“…[3][4][5][6][7][8][9][10] Several studies consider design, control, and scheduling decisions in a simultaneous optimization. 24 More advanced methods are emerging with the potential to provide higher quality solutions at the cost of higher computational complexity. For a process that is optimized only at nominal conditions, that is, uncertain parameters and disturbances set to their nominal (expected) values, the solution can become suboptimal or infeasible when it is subjected to parameter uncertainty and process disturbance, as operating limits are surpassed or stability is decreased.…”
Section: Introductionmentioning
confidence: 99%
“…This method does not guarantee an optimal solution when subject to variability, but its simplicity has made it attractive for use in industry. 24 More advanced methods are emerging with the potential to provide higher quality solutions at the cost of higher computational complexity. 25 In our previous work, a critical-set based decomposition algorithm was presented for integration of design, control and scheduling, which considered critical (worst-case) realizations of process disturbance and uncertainty.…”
Section: Introductionmentioning
confidence: 99%
“…This result was con®rmed by others ( [3]). In [4] a high concentrated feed stream and a substrate recycle were added to a single continuous fermenter to improve the controllability. In [5] different con®gurations of a continuous bioreactor with cross¯ow ®ltration recycle were studied.…”
Section: Introductionmentioning
confidence: 99%