Cooperative Evolutionary Strategy between the Bacteriome and Mycobiome

Ghannoum, Mahmoud A.

doi:10.1128/mbio.01951-16

Cited by 35 publications

(30 citation statements)

References 25 publications

(30 reference statements)

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“…Such a habitat can help them to persistently colonize and survive in specific microenvironments such as gut, skin, and oral cavity. Additionally, this "mixed species biofilm" can give extra protection against antimicrobial agents and host immune evasion [45]. Notably, this "mixed species biofilm" provides mutual benefits for both bacterial and fungal cells.…”

Section: Fungal-bacteriamentioning

confidence: 99%

Mycobiome in the Gut: A Multiperspective Review

Chin

Yong

Chong

et al. 2020

Mediators of Inflammation

105

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Human gut is home to a diverse and complex microbial ecosystem encompassing bacteria, viruses, parasites, fungi, and other microorganisms that have an undisputable role in maintaining good health for the host. Studies on the interplay between microbiota in the gut and various human diseases remain the key focus among many researchers. Nevertheless, advances in sequencing technologies and computational biology have helped us to identify a diversity of fungal community that reside in the gut known as the mycobiome. Although studies on gut mycobiome are still in its infancy, numerous sources have reported its potential role in host homeostasis and disease development. Nonetheless, the actual mechanism of its involvement remains largely unknown and underexplored. Thus, in this review, we attempt to discuss the recent advances in gut mycobiome research from multiple perspectives. This includes understanding the composition of fungal communities in the gut and the involvement of gut mycobiome in host immunity and gut-brain axis. Further, we also discuss on multibiome interactions in the gut with emphasis on fungi-bacteria interaction and the influence of diet in shaping gut mycobiome composition. This review also highlights the relation between fungal metabolites and gut mycobiota in human homeostasis and the role of gut mycobiome in various human diseases. This multiperspective review on gut mycobiome could perhaps shed new light for future studies in the mycobiome research area.

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Section: Fungal-bacteriamentioning

confidence: 99%

Mycobiome in the Gut: A Multiperspective Review

Chin

Yong

Chong

et al. 2020

Mediators of Inflammation

105

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“…Examples of bacterial-fungal cooperation within the protected environment of a biofilm include that in wounds, the oral cavity, and urinary tract infections. This evolutionary tactic provides a stable survival equilibrium among kingdoms (85,86). Therefore, explaining the rationale for the clinical relevance of multispecies biofilms is not trivial.…”

Section: Roots Of Biofilm Phenotypic Resistancementioning

confidence: 99%

Options and Limitations in Clinical Investigation of Bacterial Biofilms

et al. 2018

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Bacteria can form single- and multispecies biofilms exhibiting diverse features based upon the microbial composition of their community and microenvironment. The study of bacterial biofilm development has received great interest in the past 20 years and is motivated by the elegant complexity characteristic of these multicellular communities and their role in infectious diseases. Biofilms can thrive on virtually any surface and can be beneficial or detrimental based upon the community's interplay and the surface. Advances in the understanding of structural and functional variations and the roles that biofilms play in disease and host-pathogen interactions have been addressed through comprehensive literature searches. In this review article, a synopsis of the methodological landscape of biofilm analysis is provided, including an evaluation of the current trends in methodological research. We deem this worthwhile because a keyword-oriented bibliographical search reveals that less than 5% of the biofilm literature is devoted to methodology. In this report, we (i) summarize current methodologies for biofilm characterization, monitoring, and quantification; (ii) discuss advances in the discovery of effective imaging and sensing tools and modalities; (iii) provide an overview of tailored animal models that assess features of biofilm infections; and (iv) make recommendations defining the most appropriate methodological tools for clinical settings.

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“…And on the other hand, there are analyses showing potentially positive interactions between a range of microbial groups that are disadvantageous for the host (e.g. Ghannoum ; Liguori et al. ).…”

Section: Cross‐domain Relationships and Their Implicationsmentioning

confidence: 99%

“…And on the other hand, there are analyses showing potentially positive interactions between a range of microbial groups that are disadvantageous for the host (e.g. Ghannoum 2016;Liguori et al 2016). Not only may host-directed mutualism and cooperation not be the most appropriate expectation of host-microbiota relationships, but also any codependencies may change radically over time and context.…”

Section: Evolving Mutualistic Microbiota Interactionsmentioning

confidence: 99%

Contrasting Strategies: Human Eukaryotic Versus Bacterial Microbiome Research

Hooks

O’Malley

2019

J Eukaryotic Microbiology

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Most discussions of human microbiome research have focused on bacterial investigations and findings. Our target is to understand how human eukaryotic microbiome research is developing, its potential distinctiveness, and how problems can be addressed. We start with an overview of the entire eukaryotic microbiome literature (578 papers), show tendencies in the human‐based microbiome literature, and then compare the eukaryotic field to more developed human bacterial microbiome research. We are particularly concerned with problems of interpretation that are already apparent in human bacterial microbiome research (e.g. disease causality, probiotic interventions, evolutionary claims). We show where each field converges and diverges, and what this might mean for progress in human eukaryotic microbiome research. Our analysis then makes constructive suggestions for the future of the field.

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Cooperative Evolutionary Strategy between the Bacteriome and Mycobiome

Cited by 35 publications

References 25 publications

Mycobiome in the Gut: A Multiperspective Review

Mycobiome in the Gut: A Multiperspective Review

Options and Limitations in Clinical Investigation of Bacterial Biofilms

Contrasting Strategies: Human Eukaryotic Versus Bacterial Microbiome Research

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