Cooking methods affect phytochemical composition and anti-obesity potential of soybean ( Glycine max ) seeds in Wistar rats

Woumbo, Cerile Ypolyte; Kuate, Dieudonné; Womeni, Hilaire Macaire

doi:10.1016/j.heliyon.2017.e00382

Cited by 15 publications

(12 citation statements)

References 29 publications

(30 reference statements)

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“…Plants rich in secondary metabolites including phenolics and flavonoids demonstrate powerful antioxidant properties, both in vitro and in vivo, which is attributed to their redox properties and chemical structures [35,36,37]. The results of the previous studies are also similar to ours [28,30,31,32,33,38].…”

Section: Resultssupporting

confidence: 80%

Nutritional Composition, Total Phenolic Content, Antioxidant and α-Amylase Inhibitory Activities of Different Fractions of Selected Wild Edible Plants

2019

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Wild plants are considered the richest source of essential nutrients and other beneficial phytochemicals. Hence, the objective of this study was to evaluate the nutritional composition, antioxidant- and α-amylase inhibition activities of leaves and roots of selected Bangladeshi wild plants. These wild plants were found to have high fiber (13.78–22.26 g/100 g), protein (7.08–21.56 g/100 g) and ash (8.21–21.43 g/100 g) contents. The total phenolic and total flavonoid contents were significantly higher in the leaves than the roots. Additionally, antioxidant activity was evaluated using ferric-reducing antioxidant power, 2, 2-diphenyl-1-picrylhydrazyl radical (DPPH) and trolox equivalent antioxidant capacity assays and was strongly correlated with phenolic compounds. The leaf extracts of the selected plants also exhibited potent α-amylase inhibition (~71%) and were significantly higher than their root counterparts. Thus, the study findings concluded that the investigated plants were good sources of fiber, protein, mineral, natural antioxidant compounds and α-amylase inhibitors, and their increased intake could provide health benefits. The principal component analysis (PCA) of analyzed variables divided the samples into three clear groups, and the first two principal components accounted for 86.05% of the total data set variance.

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Section: Resultssupporting

confidence: 80%

Nutritional Composition, Total Phenolic Content, Antioxidant and α-Amylase Inhibitory Activities of Different Fractions of Selected Wild Edible Plants

2019

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“…In addition, anti-inflammatory effects, such as inhibition of prostaglandin 2 (PGE2), and IL-1β were confirmed in RAW264.7 cells for black soybean extract [ 7 ], and when black soybean extract was administered to a diet-induced obesity (DIO) mouse model, decreases in TNF-α and IL-6 were observed, which are anti-inflammatory markers [ 8 ]. In previous studies related to obesity, isoflavone components in soybeans lowered blood lipid levels, thereby decreasing the risk of obesity and cardiovascular diseases [ 9 ], and when boiled and peeled soybeans were administered to Wistar rats among soybean recipes, lower cholesterol and weight were observed [ 10 ].…”

Section: Introductionmentioning

confidence: 99%

A Correlation Study on In Vitro Physiological Activities of Soybean Cultivars, 19 Individual Isoflavone Derivatives, and Genetic Characteristics

et al. 2021

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The functionality of soybeans is an important factor in the selection and utilization of excellent soybean cultivars, and isoflavones are representative functional substances in soybeans, which exhibit effects on antioxidants, estrogen activity, and cancer, and prevent cardiovascular diseases. This study analyzed ABTS, DPPH, estrogen, ER (ER) alpha, UCP-1, and NO inhibition activities in 48 types of soybean cultivars, as well as the relationship with 19 isolated types of individual isoflavone derivatives. Statistical analysis was conducted to find individual isoflavone derivatives affecting physiological activities, revealing the high correlation of three types of derivatives: genistein 7-O-(6″-O-acetyl)glucoside (6″-O-acetylgenistin), genistein 7-O-(2″-O-apiosyl)glucoside, and glycitein. Based on these results, 15 types of soybean cultivars were selected (one control type, seven yellow types, six black types, and one green type), which have both high physiological activities and a high content of individual isoflavone derivatives. In addition, these high correlations were further verified through a genome-wide association study (GWAS) to determine the association between activities, substances, and genetic characteristics. This study comprehensively describes the relationship between the specific physiological activities of soybean resources, individual isoflavone derivative substances, and SNPs, which will be utilized for in-depth research, such as selection of excellent soybean resources with specific physiological activities.

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“…Many strategies have been put in place to manage this disease; these include the use of chemicals drugs and hypocaloric diets. Hypocaloric diets are slow in producing desired results while drugs, besides their side effects, are expensive (Kuate, Kengne, Biapa, Azantsa, & Muda, ; Woumbo, Kuate, & Womeni, ). This explains the renewed interest on research in functional foods for the diabetes management.…”

Section: Introductionmentioning

confidence: 99%

“…This explains the renewed interest on research in functional foods for the diabetes management. In addition, epidemiological studies and clinical trials have shown that dietary intake of vegetables is correlated with a reduced risk of development of chronic diseases such as cancer, type 2 diabetes, and others (Woumbo et al., ).…”

Section: Introductionmentioning

confidence: 99%

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Effect of cooking treatments on the phytochemical composition and antidiabetic potential of Vernonia amygdalina

Tekou

Kuate

Nguekouo

et al. 2018

Food Science & Nutrition

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The present study aimed at evaluating the effects of domestic culinary treatment on phytochemical contents (phenolic content and dietary fiber), and the antidiabetic potential of Vernonia amygdalina in type 2 diabetic rats. The culinary forms implied boiling leaves of V. amygdalina directly and eliminating the leaves’ bitterness before boiling. Seventy wistar rats were artificially induced with type 2 diabetes using streptozotocin and high‐fat diet. They then received by oral intubation powders of different culinary forms of leaves extract or suspensions of V. amygdalina at a dose of 500 mg /kg for a period of 4 weeks. The crude fiber, total phenol contents and the DPPH scavenging ability of these culinary forms were also measured and the results showed that values of these parameters were higher in the unwashed form than the washed form. The washed and unwashed forms of V. amygdalina significantly reduced (p < 0.05) the blood glucose, the total cholesterol, triglyceride, transaminases, urea and creatine levels. Aqueous extract has the highest ability to reduce the blood glucose level (75.76%) followed by the unwashed form (61.17%) which was greater than that of the washed form. Also, these forms significantly increased serum HDL cholesterol and total protein level, with the highest activity obtained with the unwashed form. Washing the V. amygdalina leaves (that consists of multiple trituration of leaves with water) contributes to the reduction of antidiabetic and antioxidant properties.

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Cooking methods affect phytochemical composition and anti-obesity potential of soybean ( Glycine max ) seeds in Wistar rats

Cited by 15 publications

References 29 publications

Nutritional Composition, Total Phenolic Content, Antioxidant and α-Amylase Inhibitory Activities of Different Fractions of Selected Wild Edible Plants

Nutritional Composition, Total Phenolic Content, Antioxidant and α-Amylase Inhibitory Activities of Different Fractions of Selected Wild Edible Plants

A Correlation Study on In Vitro Physiological Activities of Soybean Cultivars, 19 Individual Isoflavone Derivatives, and Genetic Characteristics

Effect of cooking treatments on the phytochemical composition and antidiabetic potential of Vernonia amygdalina

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