Conventional Audiometry, Extended High-Frequency Audiometry, and DPOAE for Early Diagnosis of NIHL

Mehrparvar, Amir Houshang; Mirmohammadi, Seyyed Jalil; Davari, Mohammad Hossein; Mostaghaci, Mehrdad; Mollasadeghi, Abolfazl; Bahaloo, Maryam; Hashemi, Seyyed Hesam

doi:10.5812/ircmj.9628

Cited by 46 publications

(54 citation statements)

References 22 publications

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“…The two most common tests are conventional audiometry, which tests thresholds in the 250-8,000 Hz range, and distortion product otoacoustic emissions (DPOAE) testing, which examines the function of OHCs. Although it is much less commonly used, extended high frequency audiometry, which tests the range from 8,000-16,000 Hz, can be useful in detecting early signs of hearing loss 78 .…”

Section: Audiogrammentioning

confidence: 99%

New treatment options for hearing loss

Müller

Barr-Gillespie

2015

Nat Rev Drug Discov

163

132

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Hearing loss is the most common form of sensory impairment in humans and affects more than 40 million people in the United States alone. No drug-based therapy has been approved by the Food and Drug Administration, and treatment mostly relies on devices such as hearing aids and cochlear implants. Over recent years, more than 100 genetic loci have been linked to hearing loss and many of the affected genes have been identified. This understanding of the genetic pathways that regulate auditory function has revealed new targets for pharmacological treatment of the disease. Moreover, approaches that are based on stem cells and gene therapy, which may have the potential to restore or maintain auditory function, are beginning to emerge.

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Section: Audiogrammentioning

confidence: 99%

New treatment options for hearing loss

Müller

Barr-Gillespie

2015

Nat Rev Drug Discov

163

132

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“…Age-related hearing loss, noise-induced hearing loss (NIHL), and ototoxicity may be observed as a highfrequency hearing loss that gradually progresses toward lower frequencies (Durrant et al, 2009;Seddon et al, 2012;Mehrparvar et al, 2014). The acoustic energy of extended high frequencies (EHFs) plays an important role in speech perception, especially in the presence of background noise (Rodríguez Valiente et al, 2014;Vitela et al, 2014;Vlaming et al, 2014).…”

mentioning

confidence: 99%

Extended High-Frequency Smartphone Audiometry: Validity and Reliability

et al. 2018

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Background: Extended high-frequency (EHF) audiometry (8?16 kHz) has an important role in audiological assessments such as ototoxicity monitoring, and for speech recognition and localization. Accurate and reliable EHF testing with smartphone technologies has the potential to provide more affordable and accessible hearing-care services, especially in underserved contexts. Purpose: To determine the accuracy and test?retest reliability of EHF audiometry with a smartphone application, using calibrated headphones. Research Design: Air-conduction thresholds (8?16 kHz) and test?retest reproducibility, recorded with conventional audiometry (CA) and smartphone audiometry (SA), using audiometric (Sennheiser HDA 300 circumaural) and nonstandard audiometric (Sennheiser HD202 II supra-aural) headphones, were compared in a repeated-measures design. Study Sample: A total of 61 participants (122 ears) were included in the study. Of these, 24 were adults attending a tuberculosis clinic (mean age = 36.8, standard deviation [SD] = 14.2 yr; 48% female) and 37 were adolescents and young adults recruited from a prospective students program (mean age = 17.6, SD = 3.2 yr; 76% female). Of these, 22.3% (n = 326) of EHF thresholds were ?25 dB HL. Data Analysis: Threshold comparisons were made between CA and SA, with audiometric headphones and nonstandard audiometric headphones. A paired samples t-test was used for comparison of threshold correspondence between conventional and smartphone thresholds, and test?retest reproducibility of smartphone thresholds. Results: Conventional thresholds corresponded with smartphone thresholds at the lowest intensity (10 dB HL), using audiometric and nonstandard audiometric headphones in 59.4% and 57.6% of cases, respectively. Conventional thresholds (exceeding 10 dB HL) corresponded within 10 dB or less, with smartphone thresholds in 82.9% of cases using audiometric headphones and 84.1% of cases using nonstandard audiometric headphones. There was no significant difference between CA and SA, using audiometric headphones across all frequencies (p > 0.05). Test?retest comparison also showed no significant differences between conditions (p > 0.05). Smartphone test?retest thresholds corresponded within 10 dB or less in 86.7% and 93.4% of cases using audiometric and nonstandard audiometric headphones, respectively. Conclusions: EHF smartphone testing with calibrated headphones can provide an accurate and reliable option for affordable mobile audiometry. The validity of EHF smartphone testing outside a sound booth as a cost-effective and readily available option to detect high-frequency hearing loss in community-based settings should be established.

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“…[17,18] Somma et al [19] found high-frequency audiometry (10,000À16,000 Hz) to change earlier than conventional audiometry in noiseinduced hearing loss (500À6000 Hz). Mehrparvar et al [20] found that among three different methods (conventional audiometry, high-frequency audiometry and OAE) used for assessing noise-exposed workers, high-frequency audiometry is the most useful one. Extended high-frequency audiometry has been suggested as a method for monitoring the effects of noise exposure, ototoxic medication and hearing loss resulting from other causes.…”

Section: Resultsmentioning

confidence: 99%

Hearing impairment in middle-aged patients with diabetes

Özkurt

Akdağ

Tuna

et al. 2016

Biotechnology & Biotechnological Equipment

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Most studies focus on elderly patients with type 2 diabetes mellitus (T2DM). There is little known about the hearing of middle-aged subjects with T2DM. The objective of this study is to evaluate hearing impairment in patients aged 40À50 years with T2DM using pure-tone audiometry and high-frequency audiometry. Forty patients with T2DM (19 males, 21 females) and 40 (20 males, 20 females) age and sex similar controls were included. All subjects completed clinical, laboratory and auditory assessments. Pure-tone audiometry auditory tests and high-frequency audiometry tests were performed in a soundproof room for each ear using the AC-40 audiometer from Interacoustics with a special earphone appropriate for high frequency. In the T2DM group, the duration of T2DM was between 5 and 15 years (7.7 § 2.4 years). At all frequencies, the thresholds of the T2DM group were higher than the control group for both right and left ears and also significant. However, the thresholds at standard frequencies (125À8000 Hz) for both group's average were lower than 20 dB-HL and were considered to be normal, and at high frequencies (9000À16,000 Hz) the T2DM group's average thresholds were higher than 20 dB-HL and considered to be a hearing loss. A Spearman's correlation test was done between the duration of T2DM and hearing thresholds. There was a mild correlation between the duration of T2DM and hearing thresholds in all frequencies. In conclusion, patients with type 2 diabetes have a high prevalence of subclinical sensorineural hearing loss. High-frequency audiometry can be used in hearing assessment screening of diabetic patients.

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Conventional Audiometry, Extended High-Frequency Audiometry, and DPOAE for Early Diagnosis of NIHL

Cited by 46 publications

References 22 publications

New treatment options for hearing loss

New treatment options for hearing loss

Extended High-Frequency Smartphone Audiometry: Validity and Reliability

Hearing impairment in middle-aged patients with diabetes

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