Convenient N-acetylation of amines in N,N-dimethylacetamide with N,N-carbonyldiimidazole

MoS2-Catalyzed transamidation reaction

“…The catalyzed transamidation reactions using DMF as carbonyl source have been reported. Various catalysts, including metal catalysts, such as Ni 13 , Ce 14 , Fe 15 , Cu 16 , L-Proline 17 , Pd 49 and metal-free catalysts, such as boronic acid 18 and their derivatives 19,20 , and imidazole 50 and its derivatives 21 have been succeed in this transformation. However, these strategies are often suffered from drawbacks such as use of unreadily available and costly catalysts, large amount of catalyst, essential additives, limited scope, and etc.…”

Two different facile and efficient approaches for the synthesis of various N-arylacetamides via N-acetylation of arylamines and straightforward one-pot reductive acetylation of nitroarenes promoted by recyclable CuFe2O4 nanoparticles in water

“…Up to now, several methods have been reported for the mentioned reaction. Nevertheless, some of these methods along with some merits have one or more drawbacks such as the use of expensive and harmful reagents, solvents or catalysts, harsh reaction conditions, low yield of products and (or) lengthy reaction times and so on [77][78][79][80][81][82][83][84][85][86][87][88][89][90][91][92][93][94][95][96]. In this regard, we decided to introduce a simple, efficient, green, costand time-effective protocol for the N-acetylation of arylamines.…”

N‐Formylation of amines using a domestic microwave oven and bioactivities of some N‐formamides

“…One of the most interesting protocols is using N,Ndimethylformamide (DMF) to produce N-formyl compounds. [6][7][8] For example, imidazole and DMF (N,N-dimethylformamide); [9] P2O5 and DMF; [10] POCl3 and DMF; [11] [Ni(quin)2], DMF and imidazole. [12] Microwave irradiation can also assist the N-formylation.…”